Results 121 to 130 of about 27,826 (225)

Controlling pre-leukemic thymocyte self-renewal [PDF]

, 2014
Goossens, Steven, Van Vlierberghe, Pieter   +1 more
core   +2 more sources

TRAFFICKING OF ALPHA SECRETASE ADAM10: NEW INSIGHTS INTO THE MOLECULAR MECHANISM OF MODULATION

, 2012
ADAM10 (a disintegrin and metalloproteinase 10) is the most accredited candidate as alpha-secretase in the amyloid cascade, since it prevents Abeta formation. ADAM10 is synthesized in an inactive form, which is proteolytically activated during its forward transport along the secretory pathway and at the plasma membrane.
openaire   +2 more sources

Alpha-secretase inhibition impairs Group I metabotropic glutamate receptor-mediated protein synthesis, long-term potentiation and long-term depression. [PDF]

Philos Trans R Soc Lond B Biol Sci
Mockett BG, Davies JWT, Mills ZB, Kweon DY, Abraham WC.   +4 more
europepmc   +1 more source

Notch signaling regulates metabolic heterogeneity in glioblastoma stem cells [PDF]

, 2017
et al,, Si, Sheng
core   +2 more sources

Amyloid Alpha: The Neglected Cousin of Amyloid Beta. [PDF]

Chembiochem
Raskatov JA.
europepmc   +1 more source

The role of Notch signalling and its crosstalk with oestrogen receptor signalling in breast cancer. [PDF]

Cancer Metastasis Rev
Azadova A, Isayev O, Marco A, Brooke GN.
europepmc   +1 more source

Investigating the binding potential of the Melissa officinalis oil against Alzheimer's targets by molecular docking and in vitro evaluations. [PDF]

Sci Rep
Kolouei A, Barati M, Abbas-Mohammadi M.
europepmc   +1 more source

Strategies to deliver peptide drugs to the brain [PDF]

, 2014
Lalatsa, Katerina, Schatzlein, Andreas G., Uchegbu, Ijeoma F.   +2 more
core   +1 more source

Integrative Network Pharmacology and Molecular Docking Analysis Uncovers Multi-Target Mechanisms of Alpha-Mangostin Against Acute Kidney Injury. [PDF]

Foods
Chatatikun M, Tedasen A, Jansakun C, Poolbua P, Huang JC, Thanasai J, Klangbud WK, Phongphithakchai A.   +7 more
europepmc   +1 more source

Evidence that extra copies of chromosome 1q play a role in the early phases of pancreatic neoplasia. [PDF]

Sci Adv
Douville C, Parksong J, Dal Molin M, Graham S, Greipp PT, Knudson R, Curtis S, Wang Y, Dobbyn L, Popoli M, Ptak J, Silliman N, Romans K, Iacobuzio-Donahue CA, Makoohon-Moore AP, Lennon AM, Goggins M, Hruban RH, Kiemen A, Bettegowda C, Kinzler KW, Papadopoulos N, Wood LD, Vogelstein B.   +23 more
europepmc   +1 more source