Results 91 to 100 of about 27,933 (291)

Phylogenetic and Timescale Analysis of Barmah Forest Virus as Inferred from Genome Sequence Analysis

open access: yesViruses, 2020
Barmah Forest virus (BFV) is a medically important mosquito-borne alphavirus endemic to Australia. Symptomatic disease can be a major cause of morbidity, associated with fever, rash, and debilitating arthralgia.
Alice Michie   +9 more
doaj   +1 more source

Alphavirus Particles Can Assemble with an Alternate Triangulation Number

open access: yesViruses, 2022
Alphaviruses are spherical, enveloped RNA viruses primarily transmitted by mosquitoes, and cause significant arthritogenic and neurotropic disease in humans and livestock.
Jason T. Kaelber   +3 more
doaj   +1 more source

Wolbachia and arbovirus inhibition in mosquitoes [PDF]

open access: yes, 2013
Wolbachia is a maternally inherited intracellular bacteria that can manipulate the reproduction of their insect hosts, and cytoplasmic incompatibility allows them to spread through mosquito populations.
Sinkins, Steven P.
core   +1 more source

Both ADP-Ribosyl-Binding and Hydrolase Activities of the Alphavirus nsP3 Macrodomain Affect Neurovirulence in Mice

open access: yesmBio, 2020
Viral encephalomyelitis is an important cause of long-term disability, as well as acute fatal disease. Identifying viral determinants of outcome helps in assessing disease severity and developing new treatments. Mosquito-borne alphaviruses infect neurons
Rachy Abraham   +5 more
semanticscholar   +1 more source

Identification of TPRA1 as a Novel Receptor and Predictive Biomarker for Oncolytic Virus M1

open access: yesAdvanced Science, Volume 12, Issue 48, December 29, 2025.
This study identifies transmembrane protein adipocyte‐associated 1 (TPRA1) as a novel receptor for oncolytic virus M1 (OVM). TPRA1's ectodomain binds OVM particles, while its intracellular domain facilitates virus internalization, promoting efficient viral entry.
Linyi Hu   +20 more
wiley   +1 more source

Alphavirus vectors for cancer therapy

open access: yesVirus Research, 2010
Alphaviruses contain a single strand RNA genome that can be easily modified to express heterologous genes at very high levels in a broad variety of cells, including tumor cells. Alphavirus vectors can be used as viral particles containing a packaged vector RNA, or directly as nucleic acids in the form of RNA or DNA. In the latter case alphavirus RNA is
Jose I, Quetglas   +5 more
openaire   +2 more sources

Outbreak of West Nile virus causing severe neurological involvement in children, Nuba Mountains, Sudan, 2002. [PDF]

open access: yes, 2004
An atypical outbreak of West Nile virus (WNV) occurred in Ngorban County, South Kordophan, Sudan, from May to August 2002. We investigated the epidemic and conducted a case-control study in the village of Limon.
Anonymous (MMWR)   +20 more
core   +2 more sources

“Fertile” Mutations in SARS‐CoV‐2 RNA More Frequently Occurred in Hairpin Loops That Determine Virus Evolution

open access: yesAPMIS, Volume 133, Issue 12, December 2025.
ABSTRACT RNA hairpins may constitute a foundation of genetic evolution both in viruses and other organisms. Stem‐loops theoretically comprise a stable part, the double‐stranded stem, and a single‐stranded loop allowing evolution. Here we tested for SARS‐CoV‐2 if “fertile” mutations were in loops while mutations in stems were poorly tolerated and rarely
Philippe Colson   +5 more
wiley   +1 more source

Usage of FTA® Classic Cards for Safe Storage, Shipment, and Detection of Arboviruses

open access: yesMicroorganisms, 2022
Infections caused by arthropod-borne RNA viruses are overrepresented among emerging infectious diseases. Effective methods for collecting, storing, and transporting clinical or biological specimens are needed worldwide for disease surveillance.
Janina Krambrich   +6 more
doaj   +1 more source

Suppression of steady-state, but not stimulus-induced NF-kappaB activity inhibits alphavirus-induced apoptosis. [PDF]

open access: yes, 1998
Recent studies have established cell type- specific, proapoptotic, or antiapoptotic functions for the transcription factor NF-kappaB. In each of these studies, inhibitors of NF-kappaB activity have been present before the apoptotic stimulus, and so the ...
DiDonato, JA   +4 more
core  

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