Results 21 to 30 of about 28,174 (288)
Current perspectives on alphavirus encapsidation, assembly and budding. [PDF]
Front Cell Infect MicrobiolBhardwaj K +3 more
europepmc +3 more sources
Synthesis of Alphavirus-Specified RNA [PDF]
Journal of Virology, 1978 UV irradiation of chicken fibroblasts infected with Semliki Forest or Sindbis virus has been used to investigate the mechanism of synthesis of 42S and 26S RNA, the major plus-strand virus-specified RNAs formed during the multiplication of standard virus particles.
Henry Brzeski, S. I. T. Kennedy
openalex +4 more sources
Entry receptors — the gateway to alphavirus infection
Journal of Clinical Investigation, 2023 Alphaviruses are enveloped, insect-transmitted, positive-sense RNA viruses that infect humans and other animals and cause a range of clinical manifestations, including arthritis, musculoskeletal disease, meningitis, encephalitis, and death. Over the past
O. Zimmerman +4 more
semanticscholar +1 more source
Alphaviruses in Immunotherapy and Anticancer Therapy
Biomedicines, 2022 Alphaviruses have been engineered as expression vectors for vaccine development and gene therapy. Due to the feature of RNA self-replication, alphaviruses can provide exceptional direct cytoplasmic expression of transgenes based on the delivery of ...
Kenneth Lundstrom
doaj +1 more source
Imaging the Alphavirus Exit Pathway [PDF]
Journal of Virology, 2014 ABSTRACT Alphaviruses are small enveloped RNA viruses with highly organized structures that exclude host cell proteins. They contain an internal nucleocapsid and an external lattice of the viral E2 and E1 transmembrane proteins. Alphaviruses bud from the plasma membrane (PM), but the process and dynamics of alphavirus assembly and budding are
María Guadalupe Martínez +4 more
openalex +4 more sources
A molecular understanding of alphavirus entry and antibody protection
Nature Reviews Microbiology, 2022 Alphaviruses are arthropod-transmitted RNA viruses that cause epidemics of human infection and disease on a global scale. These viruses are classified as either arthritogenic or encephalitic based on their genetic relatedness and the clinical syndromes ...
A. S. Kim, M. Diamond
semanticscholar +1 more source
PLoS Pathogens, 2023 Chikungunya virus (CHIKV) is a reemerging alphavirus. Since 2005, it has infected millions of people during outbreaks in Africa, Asia, and South/Central America.
E. E. Treffers +6 more
semanticscholar +1 more source
Getah Virus (Alphavirus): An Emerging, Spreading Zoonotic Virus
Pathogens, 2022 Getah virus (GETV) is a zoonotic virus transmitted by mosquitoes, belonging to the Togaviridae family, Alphavirus genus. It was first isolated from mosquitoes in Malaysia in 1955, being widespread in island countries in the South Pacific region.
Bin Li, Huanyu Wang, G. Liang
semanticscholar +1 more source
Proceedings of the National Academy of Sciences of the United States of America, 2021 Significance Alphaviruses are mosquito-borne RNA viruses that cause rash, arthritis, and neurologic disease. Despite a continued risk of outbreaks, there are no licensed interventions for any alphavirus.
A. Jayabalan +7 more
semanticscholar +1 more source
Altered Spatial and Temporal Gait Parameters in Mice Infected with Ross River Virus
mSphere, 2021 Mouse models that accurately replicate the immunopathogenesis and clinical disease of alphavirus infection are vital to the preclinical development of therapeutic strategies that target alphavirus infection and disease.
Eranga Abeyratne +6 more
doaj +1 more source