Results 51 to 60 of about 16,582 (211)

Riboflavin, a Potent Neuroprotective Vitamin: Focus on Flavivirus and Alphavirus Proteases

Microorganisms, 2022
Several neurotropic viruses are members of the flavivirus and alphavirus families. Infections caused by these viruses may cause long-term neurological sequelae in humans.
Raphael J. Eberle, Danilo S. Olivier, Marcos S. Amaral, Carolina C. Pacca, Mauricio L. Nogueira, Raghuvir K. Arni, Dieter Willbold, Monika A. Coronado   +7 more
doaj   +1 more source

Diagnosis and Management of Infectious Encephalitis in Adults: Guidelines From the European Academy of Neurology and European Society of Clinical Microbiology and Infectious Diseases

European Journal of Neurology, Volume 33, Issue 10, October 2026.
ABSTRACT Background Encephalitis is difficult to diagnose and manage, posing a challenge to clinicians. Since the last European guidelines were published in 2010, novel causes have emerged, diagnostic processes have evolved and treatments assessed which need to be reflected in updated guidelines.
Julia Granerod, Johann Sellner, Jean‐Paul Stahl, Sylviane Defres, Alexandra Mailles, Erich Schmutzhard, Elisabeth Aurelius, Thomas Whitfield, Luca Massacesi, Maarten J. Titulaer, Pille Taba, Benedict D. Michael, Tehmina Bharucha, Lance Turtle, Brendan Sargent, Arina Tamborska, Jonathan Cattrall, Yun Huang, Eva Maria Hodel, Suzannah Lant, Glynn Webb, Rajish S. K. Shil, Shalley Dhar, Diederik van de Beek, Marie Studahl, Matthijs C. Brouwer, Uta Meyding‐Lamade, Ava Easton, Bhagteshwar Singh, Tom Solomon   +29 more
wiley   +1 more source

The Role of the Opal Termination Codon in Alphavirus Pathogenesis [PDF]

, 2018
Alphaviruses are members of the Togaviridae family of viruses. These viruses are arboviruses, most often transmitted by a mosquito host. Serious outbreaks of alphavirus infection occur worldwide and affect millions of people. Currently, the greatest risk
Jones, Jennifer
core   +1 more source

Research trends on alphavirus receptors: a bibliometric analysis

Frontiers in Cellular and Infection Microbiology
BackgroundAlphaviruses are a diverse group of pathogens that have garnered considerable attention due to their impact on human health. By investigating alphavirus receptors, researchers can elucidate viral entry mechanisms and gain important clues for ...
Runqi Chen, Runqi Chen, Runqi Chen, Zirui Wang, Zirui Wang, Leiliang Zhang, Leiliang Zhang, Leiliang Zhang   +7 more
doaj   +1 more source

Alphavirus polymerase and RNA replication [PDF]

Virus Research, 2017
Alphaviruses are typically arthropod-borne, and many are important pathogens such as chikungunya virus. Alphaviruses encode four nonstructural proteins (nsP1-4), initially produced as a polyprotein P1234. nsP4 is the core RNA-dependent RNA polymerase but all four nsPs are required for RNA synthesis.
Maija K, Pietilä, Kirsi, Hellström, Tero, Ahola   +2 more
openaire   +2 more sources

Design, evaluation, and validation of specific primers for accurate detection of VHS virus in rainbow trout (Oncorhynchus mykiss)

Journal of the World Aquaculture Society, Volume 57, Issue 5, October 2026.
Abstract Accurate detection of Piscine novirhabdovirus (PNRV), also know as viral hemorrhagic septicemia virus (VHSV) in rainbow trout (Oncorhynchus mykiss) is essential for effective aquaculture disease management. This study developed strain‐inclusive primers targeting the conserved glycoprotein (G) gene using integrated bioinformatics approaches ...
Mohammad Kazem Momeni, Mohsen Mobini‐Dehkordi, Amin Nematollahi   +2 more
wiley   +1 more source

Alphavirus Particles Can Assemble with an Alternate Triangulation Number [PDF]

, 2022
Alphaviruses are spherical, enveloped RNA viruses primarily transmitted by mosquitoes, and cause significant arthritogenic and neurotropic disease in humans and livestock.
Auguste, A. Jonathan, Jason T. Kaelber, Auguste, Albert J., David Chmielewski, Albert J. Auguste, Kaelber, Jason T., Chmielewski, David, Chiu, Wah, Wah Chiu   +8 more
core   +1 more source

Status and future of recombinant adeno‐associated virus vector manufacturing

Biotechnology Progress, Volume 42, Issue 5, September/October 2026.
Abstract Sixty years of adeno‐associated virus (AAV) research illustrates a trajectory marked by basic science exploration, iterative innovation, persistent challenges, a number of clinical setbacks, as well as commercial therapeutic triumphs. This continual evolution has led to recombinant AAV (rAAV) becoming a cornerstone of modern gene therapy ...
Frank Agbogbo, David Dismuke
wiley   +1 more source

Alphavirus Genome Structure and Replication [PDF]

, 2016
The family Togaviridae consists of two genera, Alphavirus and Rubivirus (Fields et al., 2013). The organization of their respective genomes is similar, but phylogenetic analysis shows that alphaviruses and rubiviruses are quite divergent (Koonin and ...
Belinda L. Herring, Rulli, Nestor E, Mahalingam, Suresh, Chen, Weiqiang, Herring, Belinda L, Lara J. Herrero, Weiqiang Chen, Kuo-Ching Sheng, Nestor E. Rulli, Suresh Mahalingam, Herrero, Lara J, Sheng, Kuo-Ching   +11 more
core   +1 more source

Detection of two alphaviruses: Middelburg virus and Sindbis virus from enzootic amplification cycles in southwestern Uganda

Frontiers in Microbiology
Our knowledge of alphavirus genetic diversity is mainly based on viruses isolated from anthropophilic mosquito species, humans, and livestock during outbreaks.
Selina Laura Graff, Georg Joachim Eibner, James Robert Ochieng, Terry C. Jones, Terry C. Jones, Terry C. Jones, Anthony Mutebi Nsubuga, Julius Julian Lutwama, Innocent Bidason Rwego, Sandra Junglen   +9 more
doaj   +1 more source