Results 61 to 70 of about 16,582 (211)
Immunity, Inflammation and Disease, Volume 14, Issue 9, September 2026.Messenger RNA therapeutics are rapidly expanding beyond infectious diseases into oncology, autoimmune disorders, protein replacement therapy, cardiovascular and neurological diseases, and regenerative medicine. Advances in RNA engineering and targeted delivery are driving the development of safe, programmable, and precision therapeutics for diverse ...
Gedion Mengistu Dejen
wiley +1 more source
PLoS Neglected Tropical Diseases, 2017 Alphaviruses, such as chikungunya virus, and flaviviruses, such as dengue virus, are (re)-emerging arboviruses that are endemic in tropical environments.
Elysse N Grossi-Soyster +9 more
doaj +1 more source
Alphavirus-host interactions : how to unravel the proviral activity of G3BP
, 2019 The genus Alphavirus belongs to the virus family Togaviridiae, a group of arthropod-borne enveloped RNA viruses with single-stranded, positive-sense genome.
Benjamin Götte (18672085)
core +1 more source
Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.We developed sensitive real‐time PCR assays for West Nile virus and Usutu virus to screen bird and human samples in Finland. Although no positive samples were detected, active migratory flyways and recent cases in neighbouring countries highlight the risk of future introduction and the need for continued surveillance.
Ruut Joensuu +6 more
wiley +1 more source
Bioscience Reports, 2015 Alphavirus nsP2 proteins are multifunctional and essential for viral replication. The protease role of nsP2 is critical for virus replication as only the virus protease activity is used for processing of the viral non-structural polypeptide.
Chonticha Saisawang +5 more
doaj +1 more source
Noncapped Genomic RNA Are Critical for Alphaviral Infection and Pathogenicity
Proceedings, 2020 Alphaviruses are positive-sense RNA arthropod-borne viruses that represent a significant threat to public health. During alphaviral replication, significant quantities of viral genomic RNAs that lack a canonical 5’ cap structure are produced and packaged
Autumn T. LaPointe, Kevin J Sokoloski
doaj +1 more source
Synthesis of Alphavirus-Specified RNA [PDF]
Journal of Virology, 1978 UV irradiation of chicken fibroblasts infected with Semliki Forest or Sindbis virus has been used to investigate the mechanism of synthesis of 42S and 26S RNA, the major plus-strand virus-specified RNAs formed during the multiplication of standard virus particles.
H, Brzeski, S I, Kennedy
openaire +2 more sources
Journal of Fish Diseases, Volume 49, Issue 9, September 2026.ABSTRACT Ectoparasites that penetrate host skin can act as biological or mechanical vectors for pathogens and, in some cases, serve as reservoirs. Crustacean ectoparasites of fish are potential vectors of pathogens, which is especially relevant for obligate pathogens (e.g., Aeromonas salmonicida) with limited seawater survival. Sea lice (Lepeophtheirus
B. Klimesova +9 more
wiley +1 more source
siRNA Screen Identifies Trafficking Host Factors that Modulate Alphavirus Infection. [PDF]
, 2016 Little is known about the repertoire of cellular factors involved in the replication of pathogenic alphaviruses. To uncover molecular regulators of alphavirus infection, and to identify candidate drug targets, we performed a high-content imaging-based ...
Gianluca Pegoraro +39 more
core +1 more source
Decoding the Black Box of Fish Vaccines Efficacy in Basic and Applied Contexts
Reviews in Aquaculture, Volume 18, Issue 4, September 2026.ABSTRACT Vaccines are the frontline defense in aquaculture, yet predicting their real‐world performance remains a tricky puzzle. Unlike terrestrial veterinary vaccines, fish vaccines largely operate through “Black Box” processes, where we observe the outcomes but rarely understand the underlying immune mechanisms. Laboratory trials, though informative,
Jiří Kyslík +2 more
wiley +1 more source