Results 61 to 70 of about 16,243 (206)

A Rapid, Field‐Deployable Diagnostic Platform for Getah Virus Based on RT‐RAA and CRISPR EsCas13d

Microbial Biotechnology, Volume 19, Issue 8, August 2026.
This study developed a rapid, one‐step, visual detection platform termed ROSVD by integrating RT‐RAA with CRISPR–EsCas13d, enabling simplified sample preparation, high‐sensitivity, on‐site detection of GETV within 30 min without the need for sophisticated equipment.
Liu Baoling, Shao Lina, Xu Tong, Jia Qinrui, Zhu Ling, Xu Zhiwen   +5 more
wiley   +1 more source

Serological and spatial analysis of alphavirus and flavivirus prevalence and risk factors in a rural community in western Kenya.

PLoS Neglected Tropical Diseases, 2017
Alphaviruses, such as chikungunya virus, and flaviviruses, such as dengue virus, are (re)-emerging arboviruses that are endemic in tropical environments.
Elysse N Grossi-Soyster, Elizabeth A J Cook, William A de Glanville, Lian F Thomas, Amy R Krystosik, Justin Lee, C Njeri Wamae, Samuel Kariuki, Eric M Fèvre, A Desiree LaBeaud   +9 more
doaj   +1 more source

Association Between Chikungunya Infection and Rheumatoid Arthritis in Taiwan—A Cross‐Sectional Study

International Journal of Rheumatic Diseases, Volume 29, Issue 8, August 2026.
ABSTRACT Objectives Chikungunya virus (CHIKV) infection might cause chronic chikungunya arthritis resembling rheumatoid arthritis (RA). The purpose of this study is to investigate the potential role of this virus in the pathogenesis of RA in Taiwan, a non‐endemic area. Methods This cross‐sectional study enrolled 98 RA patients and 200 healthy controls.
Chang‐Yi Yen, Chang‐Chi Lin, Ping‐Chang Lin, Ching‐Yi Tsai, Li‐Teh Liu, Chen‐Hsuan Lin, Chun‐Hong Chen, Chia‐Chun Tseng, Hua‐Chen Chan, Cheng‐Chin Wu, Tsan‐Teng Ou, Jih‐Jin Tsai, Jeng‐Hsien Yen   +12 more
wiley   +1 more source

Alphavirus Genome Structure and Replication [PDF]

, 2016
The family Togaviridae consists of two genera, Alphavirus and Rubivirus (Fields et al., 2013). The organization of their respective genomes is similar, but phylogenetic analysis shows that alphaviruses and rubiviruses are quite divergent (Koonin and ...
Belinda L. Herring, Herring, Belinda L., Rulli, Nestor E., Rulli, Nestor E, Mahalingam, Suresh, Chen, Weiqiang, Herring, Belinda L, Lara J. Herrero, Weiqiang Chen, Herrero, Lara, Kuo-Ching Sheng, Nestor E. Rulli, Suresh Mahalingam, Herrero, Lara J, Sheng, Kuo-Ching   +14 more
core   +1 more source

Full length and protease domain activity of chikungunya virus nsP2 differ from other alphavirus nsP2 proteases in recognition of small peptide substrates

Bioscience Reports, 2015
Alphavirus nsP2 proteins are multifunctional and essential for viral replication. The protease role of nsP2 is critical for virus replication as only the virus protease activity is used for processing of the viral non-structural polypeptide.
Chonticha Saisawang, Pornpan Sillapee, Kwanhathai Sinsirimongkol, Sukathida Ubol, Duncan R. Smith, Albert J. Ketterman   +5 more
doaj   +1 more source

Noncapped Genomic RNA Are Critical for Alphaviral Infection and Pathogenicity

Proceedings, 2020
Alphaviruses are positive-sense RNA arthropod-borne viruses that represent a significant threat to public health. During alphaviral replication, significant quantities of viral genomic RNAs that lack a canonical 5’ cap structure are produced and packaged
Autumn T. LaPointe, Kevin J Sokoloski
doaj   +1 more source

Synthesis of Alphavirus-Specified RNA [PDF]

Journal of Virology, 1978
UV irradiation of chicken fibroblasts infected with Semliki Forest or Sindbis virus has been used to investigate the mechanism of synthesis of 42S and 26S RNA, the major plus-strand virus-specified RNAs formed during the multiplication of standard virus particles.
H, Brzeski, S I, Kennedy
openaire   +2 more sources

Vectors and Vector‐Borne Diseases: Biology, Epidemiology and Integrated Control Strategies

Journal of Applied Entomology, Volume 150, Issue 7, Page 990-1015, August 2026.
ABSTRACT Vector‐Borne Diseases (VBDs), transmitted by arthropods such as mosquitoes, ticks, fleas and sandflies, represent a significant threat to global health. These diseases can be caused by a variety of pathogens, including bacteria, viruses, protozoa, and helminths.
Roberta Rinaldi, Carmen Scieuzo, Federica De Stefano, Luca Masucci, Patrizia Falabella   +4 more
wiley   +1 more source

Economic effects of disease outbreaks on U.S. salmonid farms

Journal of the World Aquaculture Society, Volume 57, Issue 4, August 2026.
Abstract The U.S. salmonid industry is the second‐largest finfish sector of U.S. aquaculture, contributing $886 million and more than 2000 jobs to the U.S. economy in 2022. The goal of this study was to develop an economic analysis of the impact of losses from disease outbreaks to the U.S. salmonid industry.
Carole Engle, Shraddha Hegde, Jonathan van Senten, Ganesh Kumar, Christine Ellis, Gary Fornshell   +5 more
wiley   +1 more source

Alphavirus replicon approach to promoterless analysis of IRES elements [PDF]

, 2007
Here we describe a system for promoterless analysis of putative internal ribosome entry site (IRES) elements using an alphavirus (family Togaviridae) replicon vector.
Owens, G., Alterson, K.D., Kamrud, K.I., Smith, J.F., Dudek, J.M., Custer, M., Lee, J.S., Groebner, J.L.   +7 more
core   +1 more source