Results 61 to 70 of about 15,159 (204)

An international study on emerging arboviral infections and blood safety

open access: yesTransfusion, EarlyView.
Abstract Background Emerging and re‐emerging arboviral infections are a risk to blood safety. We conducted an international survey on how blood establishments respond to current and future arbovirus threats. Study Design and Methods A questionnaire on arbovirus donor deferral strategies, pathogen reduction, and donation screening was distributed to ...
Piya Rajendra   +40 more
wiley   +1 more source

Examples of recent flavivirus/alphavirus outbreaks worldwide.

open access: yes, 2020
Examples of recent flavivirus/alphavirus outbreaks worldwide.
Kalkoa Kalo (8321274)   +5 more
core   +1 more source

Detection of two alphaviruses: Middelburg virus and Sindbis virus from enzootic amplification cycles in southwestern Uganda

open access: yesFrontiers in Microbiology
Our knowledge of alphavirus genetic diversity is mainly based on viruses isolated from anthropophilic mosquito species, humans, and livestock during outbreaks.
Selina Laura Graff   +9 more
doaj   +1 more source

Land‐Based Functional Rehabilitation Versus Aquatic Therapy on the Quality of Life of Individuals With Chronic Chikungunya: A Randomized Clinical Trial

open access: yesPhysiotherapy Research International, Volume 31, Issue 3, July 2026.
ABSTRACT Background and Purpose Chikungunya may progress to a chronic phase marked by persistent pain and functional impairment, reducing the quality of life. Exercise‐based rehabilitation is essential, though comparisons between different modalities remain scarce. Exercises in an aquatic environment can be designed as a task‐oriented intervention that
Oliva Maria da Silva Sousa   +5 more
wiley   +1 more source

Poly(lactic‐co‐glycolic acid) Nanoparticles for IL‐12 Self‐Amplifying RNA Delivery in Glioblastoma Models

open access: yesAdvanced Functional Materials, Volume 36, Issue 38, 11 May 2026.
ABSTRACT Glioblastoma (GBM) remains one of the most lethal brain cancers, with median survival rarely exceeding 15 months after diagnosis. Interleukin‐12 (IL‐12) is a potent immunostimulatory cytokine capable of reshaping the tumor microenvironment (TME), yet its clinical translation is hindered by systemic toxicity and short half‐life. RNA‐based local
Fatima Hameedat   +11 more
wiley   +1 more source

Alphavirus Restriction by IFITM Proteins [PDF]

open access: yesTraffic, 2016
Interferon inducible transmembrane proteins (IFITMs) are broad‐spectrum antiviral factors. In cell culture the entry of many enveloped viruses, including orthomyxo‐, flavi‐, and filoviruses, is inhibited by IFITMs, though the mechanism(s) involved remain unclear and may vary between viruses.
Weston, S   +7 more
openaire   +4 more sources

Entry receptors - The gateway to alphavirus infection

open access: yes, 2023
Alphaviruses are enveloped, insect-transmitted, positive-sense RNA viruses that infect humans and other animals and cause a range of clinical manifestations, including arthritis, musculoskeletal disease, meningitis, encephalitis, and death. Over the past
Zimmerman, Ofer   +9 more
core   +1 more source

Dengue Virus Capsid Protein Interaction With Nucleic Acids

open access: yesBioFactors, Volume 52, Issue 3, May/June 2026.
Binding of dengue virus capsid protein (DENV C) to ssDNA alters Trp fluorescence intensity, lifetime, and anisotropy, revealing structural rearrangements in the complex and suggesting a possible association with liquid–liquid phase separation (LLPS). ABSTRACT Dengue virus (DENV) transmission has greatly increased in the last decade, partly due to the ...
Nelly M. Silva   +7 more
wiley   +1 more source

Noncapped Genomic RNA Are Critical for Alphaviral Infection and Pathogenicity

open access: yesProceedings, 2020
Alphaviruses are positive-sense RNA arthropod-borne viruses that represent a significant threat to public health. During alphaviral replication, significant quantities of viral genomic RNAs that lack a canonical 5’ cap structure are produced and packaged
Autumn T. LaPointe, Kevin J Sokoloski
doaj   +1 more source

Identification of a non-canonical G3BP-binding sequence in a Mayaro virus nsP3 hypervariable domain

open access: yesFrontiers in Cellular and Infection Microbiology, 2022
Ras-GTPase-activating SH3 domain-binding-proteins 1 (G3BP1) and 2 (G3BP2) are multifunctional RNA-binding proteins involved in stress granule nucleation, previously identified as essential cofactors of Old World alphaviruses.
Aymeric Neyret   +6 more
doaj   +1 more source

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