Results 71 to 80 of about 23,224 (252)

Betanodavirus Quantification and IFN I‐Antagonism Detection Using Luciferase Reporter Systems Based on Fish mx Promoters

Journal of Fish Diseases, EarlyView.
ABSTRACT Mx genes display strong and quick induction in response to viral infections, which varies according to the viral virulence; furthermore, mx transcription is blocked by several viruses as part of their immune evasion strategies. Therefore, the level and time course of mx induction reflect virus–host interplay. This idea prompted the development
Daniel Álvarez‐Torres, Patricia Moreno, Esther García‐Rosado, M. Carmen Alonso, Julia Béjar   +4 more
wiley   +1 more source

Self-Amplifying RNA Vaccine Candidates: Alternative Platforms for mRNA Vaccine Development

Pathogens, 2023
The present use of mRNA vaccines against COVID-19 has shown for the first time the potential of mRNA vaccines for infectious diseases. Here we will summarize the current knowledge about improved mRNA vaccines, i.e., the self-amplifying mRNA (saRNA ...
Christin Schmidt, Barbara S. Schnierle
doaj   +1 more source

A novel mechanism underlying the innate immune response induction upon viral-dependent replication of host cell mRNA: A mistake of +sRNA viruses' replicases [PDF]

, 2017
Viruses are lifeless particles designed for setting virus-host interactome assuring a new generation of virions for dissemination. This interactome generates a pressure on host organisms evolving mechanisms to neutralize viral infection, which places the
Colombo, Maria Isabel, Delgui, Laura Ruth   +1 more
core   +2 more sources

Controlled Field Trial of Pancreas Disease Vaccines in Farmed Atlantic Salmon: Effects on Growth and Mortality During a SAV2 Outbreak

Journal of Fish Diseases, EarlyView.
ABSTRACT Pancreas disease (PD), caused by salmonid alphavirus (SAV), is a concern for salmon aquaculture in Scotland, Ireland and Norway. This article presents results from a controlled field trial monitoring three study groups from vaccination to harvest.
Jostein Mulder Pettersen, Marte Follesø Sønnervik, Marius Karlsen, Hege Jørstad Sekkenes, Geir Schriwer, Petter Gjesdal, Ane Sandtrø, Magnus Vikan Røsæg   +7 more
wiley   +1 more source

Advances in Alphavirus and Flavivirus Research

Viruses
Newly emerging viruses, primarily zoonotic or vector-borne, pose a persistent threat to public health and have led to outbreaks of global concern [...]
Kim, YC, Reyes-Sandoval, A
openaire   +4 more sources

Detection of two alphaviruses: Middelburg virus and Sindbis virus from enzootic amplification cycles in southwestern Uganda

Frontiers in Microbiology
Our knowledge of alphavirus genetic diversity is mainly based on viruses isolated from anthropophilic mosquito species, humans, and livestock during outbreaks.
Selina Laura Graff, Georg Joachim Eibner, James Robert Ochieng, Terry C. Jones, Terry C. Jones, Terry C. Jones, Anthony Mutebi Nsubuga, Julius Julian Lutwama, Innocent Bidason Rwego, Sandra Junglen   +9 more
doaj   +1 more source

In Vitro and In Vivo Phenotypes of Venezuelan, Eastern and Western Equine Encephalitis Viruses Derived from cDNA Clones of Human Isolates

Viruses, 2022
The Department of Defense recently began an effort to improve and standardize virus challenge materials and efficacy determination strategies for testing therapeutics and vaccines.
Christina L. Gardner, Chengqun Sun, Matthew D. Dunn, Theron C. Gilliland, Derek W. Trobaugh, Yutaka Terada, Douglas S. Reed, Amy L. Hartman, William B. Klimstra   +8 more
doaj   +1 more source

Outbreak of West Nile virus causing severe neurological involvement in children, Nuba Mountains, Sudan, 2002. [PDF]

, 2004
An atypical outbreak of West Nile virus (WNV) occurred in Ngorban County, South Kordophan, Sudan, from May to August 2002. We investigated the epidemic and conducted a case-control study in the village of Limon.
Anonymous (MMWR), Berthet FX, Chowers MY, George S, Hayes CG, Huang C, Hubalek Z, Kohler KA, Le Guenno B, Marberg K, McGuigan CC, McLean RG, Murgue B, Murgue B, Petersen LR, Petersen LR, Platonov AE, Solomon T, Taylor RM, Watts DM, Weinberger M   +20 more
core   +2 more sources

Metabarcoding Reveals a Potentially Undescribed Columnaris‐Causing Bacterium in Peracute Skin Disease of Rainbow Trout (Oncorhynchus mykiss, Walbaum)

Journal of Fish Diseases, EarlyView.
ABSTRACT Columnaris‐causing bacteria (CCB) represent a group of four Flavobacterium species, previously classified under Flavobacterium columnaris, causing a threatening condition in salmonid farming characterised by cutaneous and gill lesions, commonly referred to as ‘saddleback disease’. A peracute skin disease outbreak with high mortality in rainbow
Samuele Zamparo, Ginevra Brocca, Fabio Marroni, Slobodanka Radovic, Ciro Castellano, Diana Torge, Serena Bianchi, David Groman, Guido Macchiarelli, Luisa Vera Muscatello, Donatella Volpatti, Massimo Orioles   +11 more
wiley   +1 more source

Phylogenetic and Timescale Analysis of Barmah Forest Virus as Inferred from Genome Sequence Analysis

Viruses, 2020
Barmah Forest virus (BFV) is a medically important mosquito-borne alphavirus endemic to Australia. Symptomatic disease can be a major cause of morbidity, associated with fever, rash, and debilitating arthralgia.
Alice Michie, Timo Ernst, I-Ly Joanna Chua, Michael D. A. Lindsay, Peter J. Neville, Jay Nicholson, Andrew Jardine, John S. Mackenzie, David W. Smith, Allison Imrie   +9 more
doaj   +1 more source