Results 81 to 90 of about 28,174 (288)
Genetic control of alphavirus pathogenesis [PDF]
Mammalian Genome, 2018 Alphaviruses, members of the positive-sense, single-stranded RNA virus family Togaviridae, represent a re-emerging public health concern worldwide as mosquito vectors expand into new geographic ranges. Members of the alphavirus genus tend to induce clinical disease characterized by rash, arthralgia, and arthritis (chikungunya virus, Ross River virus ...
Victoria K. Baxter, Mark T. Heise
openaire +2 more sources
Frontiers in MicrobiologyOur knowledge of alphavirus genetic diversity is mainly based on viruses isolated from anthropophilic mosquito species, humans, and livestock during outbreaks.
Selina Laura Graff +9 more
doaj +1 more source
PLoS Neglected Tropical Diseases, 2017 Alphaviruses, such as chikungunya virus, and flaviviruses, such as dengue virus, are (re)-emerging arboviruses that are endemic in tropical environments.
Elysse N Grossi-Soyster +9 more
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Noncapped Genomic RNA Are Critical for Alphaviral Infection and Pathogenicity
Proceedings, 2020 Alphaviruses are positive-sense RNA arthropod-borne viruses that represent a significant threat to public health. During alphaviral replication, significant quantities of viral genomic RNAs that lack a canonical 5’ cap structure are produced and packaged
Autumn T. LaPointe, Kevin J Sokoloski
doaj +1 more source
The Structural Biology of Eastern Equine Encephalitis Virus, an Emerging Viral Threat
Pathogens, 2021 Alphaviruses are arboviruses that cause arthritis and encephalitis in humans. Eastern Equine Encephalitis Virus (EEEV) is a mosquito-transmitted alphavirus that is implicated in severe encephalitis in humans with high mortality. However, limited insights
S. Saif Hasan +3 more
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Expression of Sindbis virus structural proteins via recombinant vaccinia virus: synthesis, processing, and incorporation into mature Sindbis virions [PDF]
, 1985 We have obtained a vaccinia virus recombinant which contains a complete cDNA copy of the 26S RNA of Sindbis virus within the thymidine kinase gene of the vaccinia virus genome.
Franke, Christine A. +3 more
core
Wolbachia and arbovirus inhibition in mosquitoes [PDF]
, 2013 Wolbachia is a maternally inherited intracellular bacteria that can manipulate the reproduction of their insect hosts, and cytoplasmic incompatibility allows them to spread through mosquito populations.
Sinkins, Steven P.
core +1 more source
bioRxiv, 2020 Background Madariaga virus (MADV), has recently been associated with severe human disease in Panama, where the closely related Venezuelan equine encephalitis virus (VEEV) also circulates. In June, 2017, a fatal MADV infection was confirmed in a community
J. Carrera +21 more
semanticscholar +1 more source
Bee products as alternatives in the treatment of viral infections
Journal of the Science of Food and Agriculture, Volume 106, Issue 1, Page 33-54, 15 January 2026.Abstract Medicines used in the treatment of viral infections usually reduce symptoms. There is a need to develop drugs that inhibit the viruses and do not merely relieve the symptoms. Natural bee products possess many pharmacological properties and are widely used in folk medicine. There are many studies on the antibacterial effects of bee products but
Michał Otręba +3 more
wiley +1 more source
Self-Amplifying RNA Vaccine Candidates: Alternative Platforms for mRNA Vaccine Development
Pathogens, 2023 The present use of mRNA vaccines against COVID-19 has shown for the first time the potential of mRNA vaccines for infectious diseases. Here we will summarize the current knowledge about improved mRNA vaccines, i.e., the self-amplifying mRNA (saRNA ...
Christin Schmidt, Barbara S. Schnierle
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