Results 111 to 120 of about 13,308 (216)

Pseudotyped Lentiviral Vectors: One Vector, Many Guises [PDF]

, 2017
Viruses have evolved specialized molecular mechanisms to transfer their genome efficiently into host cells. Viruses can be repurposed into viral vectors to achieve controlled gene transfer to desired cells.
Joglekar, Alok V., Sandoval, Salemiz
core  

Characterization of the Rubella Virus Nonstructural Protease Domain and Its Cleavage Site [PDF]

, 1996
The region of the rubella virus nonstructural open reading frame that contains the papain-like cysteine protease domain and its cleavage site was expressed with a Sindbis virus vector. Cys-1151 has previously been shown to be required for the activity of
Chen, Jun-Ping, Strauss, James H., Strauss, Ellen G., Frey, Teryl K.   +3 more
core  

Mechanism of membrane tube formation induced by adhesive nanocomponents

, 2012
We report numerical simulations of membrane tubulation driven by large colloidal particles. Using Monte Carlo simulations we study how the process depends on particle size, concentration and binding strength, and present accurate free energy calculations
A. H. Bahrami, Angelo Cacciuto, Anđela Šarić, H. Garoff   +3 more
core   +1 more source

Interferon regulatory factor 1 protects against chikungunya virus-induced immunopathology by restricting infection in muscle cells [PDF]

, 2017
Diamond, Michael S, Nair, Sharmila, Poddar, Subhajit, Shimak, Raeann M   +3 more
core   +2 more sources

MHC Class II–Alpha Chain Knockout Mice Support Increased Viral Replication That Is Independent of Their Lack of MHC Class II Cell Surface Expression and Associated Immune Function Deficiencies

, 2015
MHCII molecules are heterodimeric cell surface proteins composed of an α and β chain. These molecules are almost exclusively expressed on thymic epithelium and antigen presenting cells (APCs) and play a central role in the development and function of CD4
Alsharifi, Mohammed, Bettadapura, Jayaram, Koskinen, Aulikki, Müllbacher, Arno, Wijesundara, Danushka K.   +4 more
core   +1 more source

Nonreciprocity in CHIKV and MAYV Vaccine-Elicited Protection

Vaccines
Chikungunya virus (CHIKV) is a pathogenic arthritogenic alphavirus responsible for large-scale human epidemics for which a vaccine was recently approved for use.
Whitney C. Weber, Takeshi F. Andoh, Craig N. Kreklywich, Zachary J. Streblow, Michael Denton, Magdalene M. Streblow, John M. Powers, Gauthami Sulgey, Samuel Medica, Igor Dmitriev, David T. Curiel, Nicole N. Haese, Daniel N. Streblow   +12 more
doaj   +1 more source

Translational Control of Alphavirus–Host Interactions: Implications in Viral Evolution, Tropism and Antiviral Response

Viruses
Alphaviruses can replicate in arthropods and in many vertebrate species including humankind, but only in vertebrate cells do infections with these viruses result in a strong inhibition of host translation and transcription.
Iván Ventoso, Juan José Berlanga, René Toribio, Irene Díaz-López   +3 more
doaj   +1 more source

Eilat virus isolated from Culex univittatus mosquitoes from the Namibian Zambezi Region influences in vitro superinfection with alpha- and flaviviruses in a virus-species-dependent manner.

PLoS ONE
The genus Alphavirus harbors arboviruses of great concern, such as the Chikungunya virus and the equine encephalitis viruses. Transmission of pathogenic alphaviruses by mosquitoes could be influenced by insect-specific alphaviruses such as Eilat virus ...
Heiko D Guggemos, Anne Kopp, Katrin Voigt, Matthias Fendt, Selina L Graff, John K E Mfune, Christian Borgemeister, Sandra Junglen   +7 more
doaj   +1 more source

Surveillance of mosquitoes and arbovirus infection at the Ross River Dam (Stage 1), Australia. [PDF]

, 1993
Volume:

core  

Decoding Self vs. Non-Self: Alphavirus Cap0 Recognition and Immune Evasion. [PDF]

Viruses
Faraj SE, Filomatori CV.
europepmc   +1 more source