Results 141 to 150 of about 12,699 (245)

Translational Control of Alphavirus–Host Interactions: Implications in Viral Evolution, Tropism and Antiviral Response

Viruses
Alphaviruses can replicate in arthropods and in many vertebrate species including humankind, but only in vertebrate cells do infections with these viruses result in a strong inhibition of host translation and transcription.
Iván Ventoso, Juan José Berlanga, René Toribio, Irene Díaz-López   +3 more
doaj   +1 more source

GLuc expression in replicon-defective transfected cells infected with varying PFUs of alphaviruses.

, 2013
BHK-21 cells were transfected with pVaXJ-GLucΔnsp4 using Lipofectamine 2000 reagent, 6 h before mock-infection or infection with varying PFU levels of alphaviruses. GLuc activity was measured 44 h post-infection.
Wuyang Zhu (329855), Jiandong Li (264338), Ying He (125930), Juanjuan Fu (329857), Guodong Liang (167635), Huanqin Wang (329856), Dexin Li (158705), Quanfu Zhang (158693), Jia Li (160557), Jiangjiao Li (329853)   +9 more
core   +1 more source

Low capacity for molecular detection of Alphaviruses other than Chikungunya virus in 23 European laboratories, March 2022.

Alphaviruses comprise over 30 identified species spread worldwide and carry a large global health burden. With vector expansion occurring in and around Europe, it is anticipated this burden will increase.
Stephan Zientara, Cécile Baronti, Lance D Presser, Willem M R van den Akker, Kamelia R Stanoeva, Pauline Jourdan, Rémi N Charrel, EVD-LabNet, Céline M Gossner, Chantal B E M Reusken, Nazli Ayhan, Laura Pezzi, Ramona Moegling   +12 more
core   +1 more source

Syrian Hamsters Model Does Not Reflect Human-like Disease after Aerosol Exposure to Encephalitic Alphaviruses

Venezuelan (VEE), eastern (EEE), and western (WEE) equine encephalitis viruses are encephalitic New World alphaviruses that cause periodic epizootic and epidemic outbreaks in horses and humans that may cause severe morbidity and mortality.
Rebecca A. Erwin-Cohen, Bridget S. Lewis, Pamela J. Glass, Crystal W. Burke, Shelley P. Honnold, Christina L. Gardner, Russell R. Bakken   +6 more
core   +1 more source

Molecular Mechanisms of Getah Virus Pathogenesis. [PDF]

Vet Sci
Sharif MU, Liu C, Qiu Y.
europepmc   +1 more source

Encephalitic alphavirus infection induces long-term humoral and cell-mediated responses in seropositive participants from Panama. [PDF]

PLoS Negl Trop Dis
Cohen CA, Carrera JP, Galué J, Beltran D, Corrales R, Rivera LF, Chaverra Z, Suarez Y, Marciaga J, Rock ML, Ha MC, Wetzel DL, O'Brien EV, Abelson D, Bornholdt ZA, Moyer CL, Zeitlin L, Pascale JM, Dye JM, López-Vergés S, Herbert AS.   +20 more
europepmc   +1 more source

The RLR-MAVS-IRF3 axis activates the IFN pathway to restrict Tonate virus infection. [PDF]

PLoS Negl Trop Dis
Labadie T, Eloiflin R, Denis Z, Motos M, Re J, Schüssler M, Chemarin M, Moltini-Conclois I, Courgnaud V, Missé D, Laguette N, Majzoub K.   +11 more
europepmc   +1 more source

Potential threats of porcine Getah virus outbreaks and its specific antagonism of host antiviral response through proteasome-dependent degradation of P46 by nsP2. [PDF]

PLoS Pathog
Wu Y, Zhang H, Li M, Song S, Yang Q, Dong Y, Wang Y, Wang X, Zhang J, Tian J, Zhang F, Guo L, Feng L.   +12 more
europepmc   +1 more source

Encephalitic Alphaviruses: Epidemiology, Pathogenesis and Vaccine Development. [PDF]

Vaccines (Basel)
Kisra N, de Zeeuw Z, Eustace G, Gladman R, Ji Y, Pagliari S, Kim YC.   +6 more
europepmc   +1 more source

Targeting conserved interaction surfaces of alphavirus nsP4 supports the rational design of live-attenuated vaccine candidates. [PDF]

mBio
Yang X, Väljaots E, Li K, Naumenko K, Koit S, Tan YB, Liu X, de Melo Costa VR, Mahalingam S, Luo D, Merits A, Yang J.   +11 more
europepmc   +1 more source