Results 161 to 170 of about 9,502 (198)
A self-amplifying RNA vector based on rubella virus for mRNA therapeutics and vaccine applications. [PDF]
Mol Ther Nucleic AcidsJing M +6 more
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Structure, function, regulation, evolution, and therapeutic implications of PARP14. [PDF]
Genes DevKar P, Đukić N, Ahel D, Ahel I.
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Trends in Microbiology, 1995 The icosahedral structures of alphaviruses and of the external shell of the viral nucleocapsid have been defined to very high resolutions, revealing details of the interactions between the glycoproteins to form trimeric spikes and the nucleocapsid.
Strauss, James H. +2 more
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The Genetics of Alphaviruses [PDF]
Future Virology, 2011 Alphaviruses are emerging human pathogens that are transmitted by arthropod vectors. Their ability to infect a wide range of vertebrate hosts including humans, equines, birds and rodents has brought about a series of epidemic and epizootic outbreaks worldwide. Their potential to cause a pandemic has spurred the interest of researchers globally, leading
Foo, Suan Sin +7 more
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2010
Alphaviruses remain important emerging mosquito-borne, zoonotic pathogens that cause both localized human outbreaks and epizootics (e.g., Venezuelan equine encephalitis) and large human epidemics (e.g., Chikungunya). Alphaviruses are globally dispersed, and each continent has humans at risk from one or more of these arthropod-borne viruses (arboviruses)
A M, Powers, John T, Roehrig
+6 more sources
Alphaviruses remain important emerging mosquito-borne, zoonotic pathogens that cause both localized human outbreaks and epizootics (e.g., Venezuelan equine encephalitis) and large human epidemics (e.g., Chikungunya). Alphaviruses are globally dispersed, and each continent has humans at risk from one or more of these arthropod-borne viruses (arboviruses)
A M, Powers, John T, Roehrig
+6 more sources
International Reviews of Immunology, 2004
Many reports have indicated that infection with SV or SFV induces apoptosis both in cultured cells and in the CNS of mice. In general, the ability of virus strains to induce apoptosis correlates with their neurovirulence, although both apoptosis and neurovirulence are age dependent, i.e., resistance increases with age. SV can induce apoptosis simply by
Mei-Ling, Li, Victor, Stollar
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Many reports have indicated that infection with SV or SFV induces apoptosis both in cultured cells and in the CNS of mice. In general, the ability of virus strains to induce apoptosis correlates with their neurovirulence, although both apoptosis and neurovirulence are age dependent, i.e., resistance increases with age. SV can induce apoptosis simply by
Mei-Ling, Li, Victor, Stollar
openaire +2 more sources
Virus Research, 2004
Alphaviruses are small highly ordered enveloped RNA viruses, which replicate very efficiently in the infected cell. They consist of a nucleocapsid (NC) and a surrounding membrane with glycoproteins. In the NC the positive single stranded RNA genome of the virus is enclosed by a T=4 icosahedral shell of capsid (C) proteins.
Henrik, Garoff +2 more
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Alphaviruses are small highly ordered enveloped RNA viruses, which replicate very efficiently in the infected cell. They consist of a nucleocapsid (NC) and a surrounding membrane with glycoproteins. In the NC the positive single stranded RNA genome of the virus is enclosed by a T=4 icosahedral shell of capsid (C) proteins.
Henrik, Garoff +2 more
openaire +2 more sources
2020
Abstract There are 31 registered alphaviruses belonging to the family Togaviridae, 16 of which are known to cause human infection. They are RNA viruses with global geographical distribution and complex transmission cycles, usually between wild or domestic animals and one or more mosquito species; humans are infected by mosquito bites ...
Ann M. Powers +3 more
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Abstract There are 31 registered alphaviruses belonging to the family Togaviridae, 16 of which are known to cause human infection. They are RNA viruses with global geographical distribution and complex transmission cycles, usually between wild or domestic animals and one or more mosquito species; humans are infected by mosquito bites ...
Ann M. Powers +3 more
openaire +1 more source
Arthritogenic alphaviruses—an overview
Nature Reviews Rheumatology, 2012Mosquito-transmitted alphaviruses causing human rheumatic disease are globally distributed and include chikungunya virus, Ross River virus, Barmah Forest virus, Sindbis virus, o'nyong-nyong virus and Mayaro virus. These viruses cause endemic disease and, occasionally, large epidemics; for instance, the ...
Andreas, Suhrbier +2 more
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