Results 191 to 200 of about 12,699 (245)
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Oxford Textbook of Medicine, 2020
There are 31 registered alphaviruses belonging to the family Togaviridae, 16 of which are known to cause human infection. They are RNA viruses with global geographical distribution and complex transmission cycles, usually between wild or domestic animals
A. Powers +3 more
semanticscholar +2 more sources
There are 31 registered alphaviruses belonging to the family Togaviridae, 16 of which are known to cause human infection. They are RNA viruses with global geographical distribution and complex transmission cycles, usually between wild or domestic animals
A. Powers +3 more
semanticscholar +2 more sources
Vaccine Elicitation and Structural Basis for Antibody Protection Against Alphaviruses
Cell, 2023 Summary Alphaviruses are RNA viruses that represent emerging public health threats. To identify protective antibodies, we immunized macaques with a mixture of western, eastern, and Venezuelan equine encephalitis virus-like particles (VLPs), a regimen ...
Peter D. Kwong +2 more
exaly +2 more sources
Chikungunya Virus and Other Emerging Arthritogenic Alphaviruses
Nature Reviews MicrobiologyArthritogenic alphaviruses are arboviruses (arthropod-borne viruses) that are genetically and serologically related positive-strand RNA viruses and cause epidemics on a global scale.
Scott C. Weaver +2 more
exaly +2 more sources
Encephalitic Alphaviruses [PDF]
Veterinary Microbiology, 2010 This review will cover zoonotic, encephalitic alphaviruses in the family Togaviridae. Encephalitic alphaviruses, i.e. Western- (WEEV), Eastern- (EEEV), Venezuelan equine encephalitis virus (VEEV) and, more rarely, Ross River virus, Chikungunya virus and Highlands J virus (HJV), are neuroinvasive and may cause neurological symptoms ranging from mild (e ...
Slobodan Paessler, Michele A Zacks
exaly +3 more sources
2010
Alphaviruses remain important emerging mosquito-borne, zoonotic pathogens that cause both localized human outbreaks and epizootics (e.g., Venezuelan equine encephalitis) and large human epidemics (e.g., Chikungunya). Alphaviruses are globally dispersed, and each continent has humans at risk from one or more of these arthropod-borne viruses (arboviruses)
A M, Powers, John T, Roehrig
+6 more sources
Alphaviruses remain important emerging mosquito-borne, zoonotic pathogens that cause both localized human outbreaks and epizootics (e.g., Venezuelan equine encephalitis) and large human epidemics (e.g., Chikungunya). Alphaviruses are globally dispersed, and each continent has humans at risk from one or more of these arthropod-borne viruses (arboviruses)
A M, Powers, John T, Roehrig
+6 more sources
Mxra8 Is a Receptor for Multiple Arthritogenic Alphaviruses
Nature, 2018 Arthritogenic alphaviruses comprise a group of enveloped RNA viruses that are transmitted to humans by mosquitoes and cause debilitating acute and chronic musculoskeletal disease1.
Hueylie Lin +2 more
exaly +2 more sources
International Reviews of Immunology, 2004
Many reports have indicated that infection with SV or SFV induces apoptosis both in cultured cells and in the CNS of mice. In general, the ability of virus strains to induce apoptosis correlates with their neurovirulence, although both apoptosis and neurovirulence are age dependent, i.e., resistance increases with age. SV can induce apoptosis simply by
Mei-Ling, Li, Victor, Stollar
openaire +2 more sources
Many reports have indicated that infection with SV or SFV induces apoptosis both in cultured cells and in the CNS of mice. In general, the ability of virus strains to induce apoptosis correlates with their neurovirulence, although both apoptosis and neurovirulence are age dependent, i.e., resistance increases with age. SV can induce apoptosis simply by
Mei-Ling, Li, Victor, Stollar
openaire +2 more sources
Trends in Microbiology, 1995
The icosahedral structures of alphaviruses and of the external shell of the viral nucleocapsid have been defined to very high resolutions, revealing details of the interactions between the glycoproteins to form trimeric spikes and the nucleocapsid.
Strauss, James H. +2 more
openaire +3 more sources
The icosahedral structures of alphaviruses and of the external shell of the viral nucleocapsid have been defined to very high resolutions, revealing details of the interactions between the glycoproteins to form trimeric spikes and the nucleocapsid.
Strauss, James H. +2 more
openaire +3 more sources
Virus Research, 2004
Alphaviruses are small highly ordered enveloped RNA viruses, which replicate very efficiently in the infected cell. They consist of a nucleocapsid (NC) and a surrounding membrane with glycoproteins. In the NC the positive single stranded RNA genome of the virus is enclosed by a T=4 icosahedral shell of capsid (C) proteins.
Henrik, Garoff +2 more
openaire +2 more sources
Alphaviruses are small highly ordered enveloped RNA viruses, which replicate very efficiently in the infected cell. They consist of a nucleocapsid (NC) and a surrounding membrane with glycoproteins. In the NC the positive single stranded RNA genome of the virus is enclosed by a T=4 icosahedral shell of capsid (C) proteins.
Henrik, Garoff +2 more
openaire +2 more sources