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Structure and Assembly of Alphaviruses
1982The alphaviruses are enveloped animal viruses that belong to the family of Toga viruses. The molecular biology of this virus group is almost entirely based on studies with two members of this virus group, the Semliki Forest Virus (SFV) and the Sindbis virus.
H, Garoff, C, Kondor-Koch, H, Riedel
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Infection of Cells by Alphaviruses
2011It is widely accepted that alphaviruses enter cells by a process involving endocytosis and low-pH-mediated virus membrane-cell membrane fusion. This model and the data supporting it have received extensive and numerous reviews. The major points presented in support of this model are summarized briefly herein.
Dennis T, Brown, Raquel, Hernandez
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1986
To replicate, viruses must deliver their genomes into the cytoplasm of a host cell, entailing the transport of large macromolecular assemblies through one or more membrane barriers. The problem is not a trivial one, in view of the large size and polar nature of the viral components to be delivered and the fact that both the cell and viral components ...
Margaret Kielian, Ari Helenius
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To replicate, viruses must deliver their genomes into the cytoplasm of a host cell, entailing the transport of large macromolecular assemblies through one or more membrane barriers. The problem is not a trivial one, in view of the large size and polar nature of the viral components to be delivered and the fact that both the cell and viral components ...
Margaret Kielian, Ari Helenius
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An improved alphaviruses‐specific RT‐qPCR facilitates monitoring and prevention of alphaviruses
Journal of Medical VirologyAbstractMolecular surveillance is vital for monitoring arboviruses, often employing genus‐specific quantitative reverse‐transcription polymerase chain reaction (RT‐qPCR). Despite this, an overlooked chikungunya fever outbreak occurred in Yunnan province, China, in 2019 and false negatives are commonly encountered during alphaviruses screening practice,
Lyu Xie +3 more
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Alphaviruses: Host pathogenesis, immune response, and vaccine & treatment updates.
Journal of General Virology, 2021Israel Guerrero-Arguero +5 more
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Chikungunya virus and other emerging arthritogenic alphaviruses
Nature Reviews MicrobiologyWilliam M. de Souza +2 more
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