Results 71 to 80 of about 3,532,621 (239)

Comparative interactomics analysis of different ALS-associated proteins identifies converging molecular pathways [PDF]

open access: yes, 2016
Amyotrophic lateral sclerosis (ALS) is a devastating neurological disease with no effective treatment available. An increasing number of genetic causes of ALS are being identified, but how these genetic defects lead to motor neuron degeneration and ...
Anink, Jasper J.   +17 more
core   +3 more sources

AL-ADAB AL-ARABY AL-KLASIKY: BAINA AL-MA'NA AL-LUGAHWI WA AL-MA'NA AL-SIYAQY

open access: yesJournal of Arabic Literature (JaLi)
This research explores the deep meanings in classical Arabic literature while considering the socio-cultural context. The primary focus is on the changes in meaning and symbolism in literary works over time. Through a contextual semantic approach, the researcher analyzes classical Arabic literary texts to reveal the relationship between literal and ...
Amalia Lailatul Muna, Akmaliyah .
openaire   +1 more source

AL-USHÛL AL-FIKRIYAH WA AL-QADHÂYÂ AL-MANTHIQIYAH LI AL-TADZKÎR WA AL-TA'NÎTS FÎ AL-LUGHAH AL-'ARABIYAH

open access: yesArabi : Journal of Arabic Studies, 2018
This article aimed to discuss the theory of mudzakkar and muannats in Arabic. The classification of mudzakkar and muannats is found in most languages, not only in the Smith-Hmit languages family, but also in the Indo-European languages with varying quality and quantity.
Damhuri Damhuri, Ratni Bt. H. Bahri
openaire   +3 more sources

An adenine model of inborn metabolism errors alters TDP-43 aggregation and reduces its toxicity in yeast revealing insights into protein misfolding diseases

open access: yesMicrobial Cell
TDP-43 is linked to human diseases such as amyotrophic lateral sclerosis (ALS) and frontotemporal degeneration (FTD). Expression of TDP-43 in yeast is known to be toxic, cause cells to elongate, form liquid-like aggregates, and inhibit autophagy and ...
Sangeun Park   +3 more
doaj   +1 more source

Characterizing the Spatial Variations of Forest Sunlit and Shaded Components Using Discrete Aerial Lidar

open access: yesRemote Sensing, 2020
Forest three-dimensional (3-D) structure, in the vertical dimension, consists of at least two components, including overstory and a forest background matrix (i.e., shrubs, grass, and bare earth).
Xiaofei Wang   +5 more
doaj   +1 more source

Nesterov Acceleration of Alternating Least Squares for Canonical Tensor Decomposition: Momentum Step Size Selection and Restart Mechanisms

open access: yes, 2019
We present Nesterov-type acceleration techniques for Alternating Least Squares (ALS) methods applied to canonical tensor decomposition. While Nesterov acceleration turns gradient descent into an optimal first-order method for convex problems by adding a ...
De Sterck, Hans, Mitchell, Drew, Ye, Nan
core   +1 more source

Al-Âyah al-Mutasyâbihât al-Lafzhiyyah fi Sûrah al-An’âm ‘Inda al-Kirmâny

open access: yesStudia Quranika, 2017
This paper discusses about the verses of mutasyâbihât in the Quran. The debate of this versescaused various opinions. The meaning of the mutasyâbihât in this paper is the similarity and difference of the words in the Qur'an. Mufasir have different opinion about the meaning of the verse of mutasyâbihât al-lafdzi.
Hikmatiar Pasya, Muhammad Iqbal Rivai
openaire   +3 more sources

Retinal Damage in Amyotrophic Lateral Sclerosis: Underlying Mechanisms

open access: yesEye and Brain, 2021
Vladislav O Soldatov,1,2 Michail S Kukharsky,3,4 Andrey E Belykh,5 Andrey M Sobolev,4 Alexey V Deykin2,6 1Core Facility Centre, Institute of Gene Biology, Russian Academy of Sciences, Moscow, Russia; 2Department of Pharmacology and Clinical Pharmacology,
Soldatov VO   +4 more
doaj  

A High-throughput qPCR-based Method to Genotype the SOD1G93A Mouse Model for Relative Copy Number

open access: yesBio-Protocol, 2019
The most commonly used mouse model in ALS preclinical research expresses multiple copies of the human SOD1 (G93A) transgene. During the course of breeding, successive generations of mice can lose copies of the transgene. Because shorter lifespan of these
Valerie Tassinari, Fernando Vieira
doaj   +1 more source

Monitoring of secondary forest succession on abandoned farmland using LiDAR point clouds [PDF]

open access: yesGeodesy and Cartography, 2018
The purpose of the study was an assessment of LiDAR point clouds for automating the mapping of land use and land cover changes, mainly land abandonment and the process of secondary forest succession.
Marta Szostak   +2 more
doaj   +1 more source

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