Results 81 to 90 of about 2,739,321 (263)

Oyster (Crassostrea virginica) aquaculture in Texas: A comparison of the effects of density and gear type upon growth, shell shape, condition index and survival

Journal of the World Aquaculture Society, Volume 57, Issue 3, June 2026.
Abstract Commercial oyster farming is a new industry in Texas. Because of this, few guidelines regarding management practices for producers have been established. The purpose of this study was to evaluate the effect of different gear types and stocking densities on various oyster production indices.
Ellis L. Chapman Jr., Bailey E. Schacht, Joe M. Fox   +2 more
wiley   +1 more source

Ataxin-2 intermediate-length polyglutamine expansions are associated with increased risk for ALS

Nature, 2010
The causes of amyotrophic lateral sclerosis (ALS), a devastating human neurodegenerative disease, are poorly understood, although the protein TDP-43 has been suggested to have a critical role in disease pathogenesis. Here we show that ataxin 2 (ATXN2), a
Andrew C. Elden, Hyung-Jun Kim, Michael P. Hart, A. Chen-Plotkin, Brian S Johnson, X. Fang, Maria Armakola, F. Geser, Robert Greene, M. Lu, A. Padmanabhan, Dana Clay, L. McCluskey, L. Elman, D. Juhr, P. Gruber, U. Rüb, G. Auburger, J. Trojanowski, V. Lee, V. V. Van Deerlin, N. Bonini, A. Gitler   +22 more
semanticscholar   +1 more source

Altered perivascular fibroblast activity precedes ALS disease onset

Nature Medicine, 2021
Apart from well-defined factors in neuronal cells1, only a few reports consider that the variability of sporadic amyotrophic lateral sclerosis (ALS) progression can depend on less-defined contributions from glia2,3 and blood vessels4.
A. Månberg, N. Skene, Folkert Sanders, Marta Trusohamn, Julia Remnestål, Anna Szczepińska, I. Aksoylu, P. Lönnerberg, Lwaki Ebarasi, Stefan Wouters, Manuela Lehmann, J. Olofsson, Inti von Gohren Antequera, Aylin Domaniku, M. De Schaepdryver, Joke de Vocht, K. Poesen, M. Uhlén, J. Anink, C. Mijnsbergen, Hermieneke Vergunst-Bosch, A. Hübers, Ulf Kläppe, E. Rodriguez-Vieitez, J. Gilthorpe, E. Hedlund, R. Harris, E. Aronica, P. van Damme, A. Ludolph, J. Veldink, C. Ingre, P. Nilsson, S. Lewandowski   +33 more
semanticscholar   +1 more source

Iqa’ al-Shi’r al-‘Arabi: Al-Usus, al-Mukawwanat, al-Khasa’is, al-Jamaliyat

Cordova Journal language and culture studies, 2018
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openaire   +1 more source

Genome-wide Analyses Identify KIF5A as a Novel ALS Gene

Neuron, 2018
SUMMARY To identify novel genes associated with ALS, we undertook two lines of investigation. We carried out a genome-wide association study comparing 20,806 ALS cases and 59,804 controls.
A. Nicolas, K. Kenna, A. Renton, N. Ticozzi, F. Faghri, Ruth Chia, J. Dominov, Brendan J. Kenna, M. Nalls, Pamela J. Keagle, Alberto M Rivera, W. Rheenen, N. Murphy, J. Vugt, Joshua T. Geiger, R. V. D. Spek, Hannah A. Pliner, Shankaracharya, Bradley N. Smith, G. Marangi, S. Topp, Yevgeniya A. Abramzon, A. Gkazi, J. Eicher, A. Kenna, G. Mora, A. Calvo, L. Mazzini, N. Riva, J. Mandrioli, C. Caponnetto, S. Battistini, P. Volanti, V. Bella, F. Conforti, G. Borghero, S. Messina, I. Simone, F. Trojsi, F. Salvi, F. Logullo, S. D'alfonso, L. Corrado, M. Capasso, L. Ferrucci, C. Moreno, S. Kamalakaran, D. Goldstein, A. Gitler, Tim Harris, R. Myers, Hemali Phatnani, R. Musunuri, Uday S. Evani, A. Abhyankar, M. Zody, J. Kaye, S. Finkbeiner, S. Wyman, A. LeNail, Leandro Lima, E. Fraenkel, C. Svendsen, L. Thompson, J. Eyk, J. Berry, Timothy A. Miller, S. Kolb, M. Cudkowicz, E. Baxi, M. Benatar, J. Taylor, E. Rampersaud, Gang Wu, J. Wuu, G. Lauria, F. Verde, I. Fogh, C. Tiloca, G. Comi, G. Soraru', Cristina Cereda, P. Corcia, Hannu Laaksovirta, L. Myllykangas, Lilja Jansson, M. Valori, J. Ealing, Hisham H. M. Hamdalla, S. Rollinson, S. Pickering-Brown, R. Orrell, K. Sidle, A. Malaspina, J. Hardy, A. Singleton, Janel O. Johnson, S. Arepalli, P. Sapp, D. McKenna-Yasek, Meraida Polak, S. Asress, S. Al-Sarraj, A. King, C. Troakes, C. Vance, J. Belleroche, F. Baas, A. T. Asbroek, J. Muñoz-Blanco, D. Hernandez, Jinhui Ding, J. R. Gibbs, Sonja W. Scholz, M. Floeter, R. Campbell, F. Landi, R. Bowser, S. Pulst, J. Ravits, D. Macgowan, J. Kirby, E. Pioro, R. Pamphlett, J. Broach, Glenn Gerhard, T. Dunckley, C. Brady, N. Kowall, J. Troncoso, I. Ber, K. Mouzat, S. Lumbroso, T. Heiman-Patterson, F. Kamel, L. Bosch, R. Baloh, T. Strom, T. Meitinger, A. Shatunov, K. V. Eijk, M. Carvalho, M. Kooyman, Bas M Middelkoop, M. Moisse, R. Mclaughlin, M. A. Es, Markus Weber, K. Boylan, M. Blitterswijk, R. Rademakers, K. Morrison, A. Başak, J. Mora, V. Drory, P. Shaw, M. Turner, K. Talbot, O. Hardiman, K. Williams, J. Fifita, G. Nicholson, I. Blair, G. Rouleau, J. Esteban-Pérez, A. García-Redondo, A. Al-Chalabi, E. Rogaeva, L. Zinman, L. Ostrow, N. Maragakis, J. Rothstein, Z. Simmons, Johnathan Cooper-Knock, A. Brice, Stephen A. Goutman, E. Feldman, S. Gibson, F. Taroni, A. Ratti, C. Gellera, P. Damme, W. Robberecht, P. Fratta, M. Sabatelli, C. Lunetta, A. Ludolph, P. Andersen, Jochen H Weishaupt, W. Camu, J. Trojanowski, V. Deerlin, Robert H. Brown, L. H. Berg, J. Veldink, M. Harms, J. Glass, David J. Stone, P. Tienari, V. Silani, A. Chiò, C. Shaw, B. Traynor, J. Landers, I. Simone, G. Logroscino, I. Bartolomei, M. R. Murru, E. Costantino, C. Pani, Roberta Puddu, Carla Caredda, V. Piras, S. Tranquilli, S. Cuccu, Daniela Corongiu, M. Melis, A. Milia, F. Marrosu, M. Marrosu, G. Floris, A. Cannas, G. Mancardi, P. Origone, P. Mandich, S. Cavallaro, Kalliopi Marinou, Riccardo Sideri, S. Penco, L. Mosca, G. L. Pinter, M. Corbo, P. Carrera, N. Fini, Antonio Fasano, L. Tremolizzo, A. Arosio, C. Ferrarese, G. Tedeschi, M. Monsurrò, G. Piccirillo, C. Femiano, A. Ticca, E. Ortu, R. Spataro, T. Colletti, M. Zollino, A. Conte, M. Luigetti, S. Lattante, M. Santarelli, A. Petrucci, M. Pugliatti, A. Pirisi, Leslie D. Parish, Patrizia Occhineri, F. Giannini, C. Ricci, Michele Benigni, Tea B. Cau, D. Loi, C. Moglia, M. Brunetti, M. Barberis, G. Restagno, F. Casale, G. Marrali, G. Fuda, I. Ossola, S. Cammarosano, A. Canosa, A. Ilardi, U. Manera, M. Grassano, R. Tanel, Fabrizio Pisano, N. Shneider, Stephen A. Goutman, S. Chandran, S. Pal, G. Manousakis, S. Appel, E. Simpson, Leo Wang, S. Gibson, R. Bedlack, D. Lacomis, D. Sareen, A. Sherman, L. Bruijn, M. Penny, A. Allen, S. Appel, R. Bedlack, B. Boone, Robert H. Brown, J. Carulli, A. Chesi, W. Chung, Elizabeth T. Cirulli, G. Cooper, Julien Couthouis, A. Day-Williams, P. Dion, Yujun Han, Sebastian Hayes, Angela L. Jones, Jonathan E. M. Keebler, Brian J. Krueger, Brittany N. Lasseigne, S. Levy, Yi-Fan Lu, T. Maniatis, S. Petrovski, Alya R. Raphael, Zhong Ren, K. Sims, J. Staropoli, L. Waite, Quanli Wang, Jack R. Wimbish, Winnie W. Xin, J. Kwan, J. Broach, Ximena Arcila-Londono, Eddie B. Lee, N. Zaitlen, G. Cox, S. Finkbeiner, E. Dardiotis, E. Hornstein, D. Macgowan, T. Heiman-Patterson, M. Hammell, N. Patsopoulos, J. Dubnau, A. Nath, S. Wyman, A. LeNail, J. Eyk, S. Züchner, R. Schule, J. McCauley, Sumaira Hussain, Anne E. Cooley, Marielle Wallace, C. Clayman, R. Barohn, J. Statland, J. Ravits, A. Swenson, Carlayne Jackson, Jaya R. Trivedi, Shaida Khan, J. Katz, Liberty Jenkins, T. Burns, K. Gwathmey, J. Caress, C. Mcmillan, L. Elman, E. Pioro, J. Heckmann, Y. So, D. Walk, S. Maiser, Jinghui Zhang, F. Marchi, S. Corti, M. Ceroni, G. Siciliano, M. Filosto, Maurizio Inghilleri, S. Peverelli, C. Colombrita, B. Poletti, L. Maderna, R. Bo, S. Gagliardi, G. Querin, C. Bertolin, V. Pensato, B. Castellotti, V. Meininger, G. Besson, E. Lagrange, P. Clavelou, N. Guy, P. Couratier, P. Vourc’h, V. Danel, E. Bernard, G. Lemasson, Ahmad Al Kheifat, P. Andersen, A. Chiò, J. Cooper-Knock, Annelot M. Dekker, V. Drory, Alberto G Redondo, M. Gotkine, Winston A Hide, Alfredo Iacoangeli, J. Glass, K. Kenna, M. Kiernan, J. Landers, R. Mclaughlin, J. Mill, Miguel Mitne Neto, Mattieu Moisse, J. M. Pardina, K. Morrison, S. Newhouse, S. Pinto, S. Pulit, P. Shaw, Chris E. Shaw, W. Sproviero, Gijs H. P. Tazelaar, P. Damme, L. Berg, R. V. D. Spek, K. V. Eijk, M. A. Es, J. Vugt, J. Veldink, M. Zatz, Denis C. Bauer, Natalie A. Twine   +429 more
semanticscholar   +1 more source

The Violent ‘Trojan Horse’: a Comparative, Transnational Reading of Two Paralysis Narratives

European Journal of Life Writing
This article proposes a comparative analysis of two ALS narratives: one written in 2017 by the Spanish businessman and author Francisco Luzón, El Viaje es la recompensa (The Trip is the Reward) and the other published in 1999 by American sociologist ...
Isabel Durán Giménez-Rico
doaj   +1 more source

The Timing and Extent of Motor Neuron Vulnerability in ALS Correlates with Accumulation of Misfolded SOD1 Protein in the Cortex and in the Spinal Cord

Cells, 2020
Understanding the cellular and molecular basis of selective vulnerability has been challenging, especially for motor neuron diseases. Developing drugs that improve the health of neurons that display selective vulnerability relies on in vivo cell-based ...
Baris Genc, Oge Gozutok, Nuran Kocak, P. Hande Ozdinler   +3 more
doaj   +1 more source

Microphysiological 3D model of amyotrophic lateral sclerosis (ALS) from human iPS-derived muscle cells and optogenetic motor neurons

Science Advances, 2018
3D physiological models of neuromuscular junctions could facilitate drug screening and research on pathogenesis of ALS. Amyotrophic lateral sclerosis (ALS), a progressive neurodegenerative disease involving loss of motor neurons (MNs) and muscle atrophy,
Tatsuya Osaki, S. Uzel, R. Kamm
semanticscholar   +1 more source

The project MinE databrowser: bringing large-scale whole-genome sequencing in ALS to researchers and the public [PDF]

, 2019
Amyotrophic lateral sclerosis (ALS) is a rapidly progressive fatal neurodegenerative disease affecting one in 350 people. The aim of Project MinE is to elucidate the pathophysiology of ALS through whole-genome sequencing at least 15,000 ALS patients and ...
Project MinE ALS Sequencing Consortium¶
core  

Genetics of amyotrophic lateral sclerosis: more than twenty years of studies

The EuroBiotech Journal, 2017
Amyotrophic lateral sclerosis, also known as motor neuron disease or Lou Gehrig’s disease, is an adult-onset neurodegenerative disease that targets motor neurons in the spinal cord, cortex and brain stem.
Mazzini Letizia, Marchi Fabiola De, Corrado Lucia, D’Alfonso Sandra   +3 more
doaj   +1 more source