Results 71 to 80 of about 29,584 (137)

Age-dependent degeneration of an identified adult leg motor neuron in a Drosophila SOD1 model of ALS

open access: yesBiology Open, 2020
Mutations in superoxide dismutase 1 (SOD1) cause familial amyotrophic lateral sclerosis (ALS) in humans. ALS is a neurodegenerative disease characterized by progressive motor neuron loss leading to paralysis and inevitable death in affected individuals ...
Anthony Agudelo   +7 more
doaj   +1 more source

Aboveground biomass mapping by integrating ICESat-2, SENTINEL-1, SENTINEL-2, ALOS2/PALSAR2, and topographic information in Mediterranean forests

open access: yesGIScience & Remote Sensing, 2022
The Ice, Cloud, and Land Elevation Satellite-2 (ICESat-2) provides an extraordinary opportunity to support global large-scale forest carbon mapping, but further research is needed in order to obtain wall-to-wall forest aboveground biomass (AGB) maps with
Juan Guerra-Hernández   +8 more
doaj   +1 more source

AL-USHÛL AL-FIKRIYAH WA AL-QADHÂYÂ AL-MANTHIQIYAH LI AL-TADZKÎR WA AL-TA'NÎTS FÎ AL-LUGHAH AL-'ARABIYAH

open access: yesArabi : Journal of Arabic Studies, 2018
This article aimed to discuss the theory of mudzakkar and muannats in Arabic. The classification of mudzakkar and muannats is found in most languages, not only in the Smith-Hmit languages family, but also in the Indo-European languages with varying quality and quantity.
Damhuri Damhuri, Ratni Bt. H. Bahri
openaire   +3 more sources

Proteomic Analysis of Corpora Amylacea Extracted From Post‐mortem Brain of MAiD‐end‐of‐life Sporadic ALS Patients

open access: yesBrain and Behavior, Volume 16, Issue 5, May 2026.
Corpora amylacea extracted from the brain of ALS patients carry a specific proteomic signature. Created in BioRender. Paquet, A. (2025) https://BioRender.com/x6dh8e0 ABSTRACT Purpose Corpora amylacea (CA) are starch‐like inclusions that accumulate in the central nervous system (CNS) with aging and are enriched in neurodegenerative conditions, including
Alexandre Paquet   +5 more
wiley   +1 more source

An adenine model of inborn metabolism errors alters TDP-43 aggregation and reduces its toxicity in yeast revealing insights into protein misfolding diseases

open access: yesMicrobial Cell
TDP-43 is linked to human diseases such as amyotrophic lateral sclerosis (ALS) and frontotemporal degeneration (FTD). Expression of TDP-43 in yeast is known to be toxic, cause cells to elongate, form liquid-like aggregates, and inhibit autophagy and ...
Sangeun Park   +3 more
doaj   +1 more source

Retinal Damage in Amyotrophic Lateral Sclerosis: Underlying Mechanisms

open access: yesEye and Brain, 2021
Vladislav O Soldatov,1,2 Michail S Kukharsky,3,4 Andrey E Belykh,5 Andrey M Sobolev,4 Alexey V Deykin2,6 1Core Facility Centre, Institute of Gene Biology, Russian Academy of Sciences, Moscow, Russia; 2Department of Pharmacology and Clinical Pharmacology,
Soldatov VO   +4 more
doaj  

CD38 in Neurodegeneration and Neuroinflammation

open access: yesCells, 2020
Neurodegenerative diseases are characterized by neuronal degeneration as well as neuroinflammation. While CD38 is strongly expressed in brain cells including neurons, astrocytes as well as microglial cells, the role played by CD38 in neurodegeneration ...
Serge Guerreiro   +3 more
doaj   +1 more source

Expert Consensus on Key Attributes of Nurses in Resuscitation Teams: Findings From a Delphi Study

open access: yesNursing in Critical Care, Volume 31, Issue 3, May 2026.
ABSTRACT Background In‐hospital cardiac arrest (IHCA) requires coordinated interdisciplinary action. Nurses are often first responders and essential members of resuscitation teams, yet the attributes that define their effectiveness remain unclear.
George Kipourgos   +5 more
wiley   +1 more source

Genetic alterations of C9orf72, SOD1, TARDBP, FUS, and UBQLN2 genes in patients with Amyotrophic Lateral Sclerosis

open access: yesCogent Medicine, 2019
Amyotrophic lateral sclerosis is the most common motor neuron disease of the adulthood. Genetic analyses performed on cases with sporadic ALS (sALS) and familial ALS (fALS) have revealed mutations most commonly in the genes C9orf72, SOD1, TARDBP, FUS ...
Ciftci Vildan   +4 more
doaj   +1 more source

A High-throughput qPCR-based Method to Genotype the SOD1G93A Mouse Model for Relative Copy Number

open access: yesBio-Protocol, 2019
The most commonly used mouse model in ALS preclinical research expresses multiple copies of the human SOD1 (G93A) transgene. During the course of breeding, successive generations of mice can lose copies of the transgene. Because shorter lifespan of these
Valerie Tassinari, Fernando Vieira
doaj   +1 more source

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