Results 81 to 90 of about 3,505,696 (258)

The Violent ‘Trojan Horse’: a Comparative, Transnational Reading of Two Paralysis Narratives

European Journal of Life Writing
This article proposes a comparative analysis of two ALS narratives: one written in 2017 by the Spanish businessman and author Francisco Luzón, El Viaje es la recompensa (The Trip is the Reward) and the other published in 1999 by American sociologist ...
Isabel Durán Giménez-Rico
doaj   +1 more source

The Timing and Extent of Motor Neuron Vulnerability in ALS Correlates with Accumulation of Misfolded SOD1 Protein in the Cortex and in the Spinal Cord

Cells, 2020
Understanding the cellular and molecular basis of selective vulnerability has been challenging, especially for motor neuron diseases. Developing drugs that improve the health of neurons that display selective vulnerability relies on in vivo cell-based ...
Baris Genc, Oge Gozutok, Nuran Kocak, P. Hande Ozdinler   +3 more
doaj   +1 more source

Nesterov Acceleration of Alternating Least Squares for Canonical Tensor Decomposition: Momentum Step Size Selection and Restart Mechanisms

, 2019
We present Nesterov-type acceleration techniques for Alternating Least Squares (ALS) methods applied to canonical tensor decomposition. While Nesterov acceleration turns gradient descent into an optimal first-order method for convex problems by adding a ...
De Sterck, Hans, Mitchell, Drew, Ye, Nan
core   +1 more source

Comparative interactomics analysis of different ALS-associated proteins identifies converging molecular pathways [PDF]

, 2016
Amyotrophic lateral sclerosis (ALS) is a devastating neurological disease with no effective treatment available. An increasing number of genetic causes of ALS are being identified, but how these genetic defects lead to motor neuron degeneration and ...
Anink, Jasper J., Aronica, Eleonora, Blokhuis, Anna M., Bozzoni, Irene, Demmers, Jeroen A. A., Den Hertog, Jeroen, DINI MODIGLIANI, Stefano, Fumoto, Katsumi, Groen, Ewout J. N., Koppers, Max, Pasterkamp, R. Jeroen, Snelting, Anne, Sodaar, Peter, van Den Berg, Leonard H., van Den Heuvel, Dianne M. A., van Diggelen, Femke, Veldink, Jan H., Verheijen, Bert M.   +17 more
core   +3 more sources

AL-ADAB AL-ARABY AL-KLASIKY: BAINA AL-MA'NA AL-LUGAHWI WA AL-MA'NA AL-SIYAQY

Journal of Arabic Literature (JaLi)
This research explores the deep meanings in classical Arabic literature while considering the socio-cultural context. The primary focus is on the changes in meaning and symbolism in literary works over time. Through a contextual semantic approach, the researcher analyzes classical Arabic literary texts to reveal the relationship between literal and ...
Amalia Lailatul Muna, Akmaliyah .
openaire   +1 more source

AL-USHÛL AL-FIKRIYAH WA AL-QADHÂYÂ AL-MANTHIQIYAH LI AL-TADZKÎR WA AL-TA'NÎTS FÎ AL-LUGHAH AL-'ARABIYAH

Arabi : Journal of Arabic Studies, 2018
This article aimed to discuss the theory of mudzakkar and muannats in Arabic. The classification of mudzakkar and muannats is found in most languages, not only in the Smith-Hmit languages family, but also in the Indo-European languages with varying quality and quantity.
Damhuri Damhuri, Ratni Bt. H. Bahri
openaire   +3 more sources

Immunvermittelte Sinus- und Hirnvenenthrombosen: VITT und prä-VITT als Modellerkrankung [PDF]

, 2022
Farid Salih, Linda Schönborn, Matthias Endres, Andreas Greinacher   +3 more
openalex   +1 more source

A cellular model of TDP‐43 induces phosphorylated TDP‐43 aggregation with distinct changes in solubility and autophagy dysregulation

The FEBS Journal, Volume 292, Issue 18, Page 4870-4897, September 2025.
TDP‐43 protein plays a pathological role in sporadic and familial amyotrophic lateral sclerosis (ALS). Here, we developed a cellular model overexpressing TDP‐43 with three mutations linked to familial ALS, termed ‘3X‐TDP‐43’. Mutant 3X‐TDP‐43 expression showed deficits in autophagy flux and colocalization with stress granules.
Matthew B. Dopler, Muhammad I. Abeer, Sanaz Arezoumandan, Keyshawn Cox, Tyler L. Petersen, Esther H. Daniel, Carlton L. Cannon III, Angelica Bautista, Kennedy D. Blancher, Alysia M. Bland, Kylie J. Bond, Dominque A. Davis, Jessica M. Francois, Eliana J. McCray, Justin M. Morgan, Jessica L. Pulliam, Zymir A. Robinson, Mykia J. Taylor, James A. Dowell, Nigel J. Cairns, Michael A. Gitcho   +20 more
wiley   +1 more source

Altered EEG Response of the Parietal Network in Asymptomatic C9orf72 Carriers

Human Brain Mapping, Volume 46, Issue 11, 01 August 2025.
Our study provides the first evidence of EEG changes in asymptomatic C9orf72 repeat expansion carriers. Despite no clinical signs, these individuals exhibit altered activity in parietal regions associated with motor response control. ABSTRACT Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by motor neuron degeneration ...
Stefan Dukic, Kevin van Veenhuijzen, Henk‐Jan Westeneng, Roisin McMackin, Ruben P. A. van Eijk, Boudewijn T. H. M. Sleutjes, Bahman Nasseroleslami, Orla Hardiman, Leonard H. van den Berg   +8 more
wiley   +1 more source

Characterizing the Spatial Variations of Forest Sunlit and Shaded Components Using Discrete Aerial Lidar

Remote Sensing, 2020
Forest three-dimensional (3-D) structure, in the vertical dimension, consists of at least two components, including overstory and a forest background matrix (i.e., shrubs, grass, and bare earth).
Xiaofei Wang, Guang Zheng, Zengxin Yun, Zhaoshang Xu, L. Monika Moskal, Qingjiu Tian   +5 more
doaj   +1 more source