Results 171 to 180 of about 433,637 (362)

HMGB1 Derived from the Pyroptotic Microenvironment Promotes Macrophage Extracellular Traps in Hirschsprung‐Associated Enterocolitis

open access: yesAdvanced Biology, EarlyView.
HMGB1 derived from the pyroptotic environment in Hirschsprung‐associated enterocolitis mediates the formation of macrophage extracellular traps through TLR4 ‐p38 MAPK/p65 NF‐kB signaling pathways. Macrophage extracellular traps induce increased ROS production and pyroptosis of colonic epithelial cells.
Rui Zhang   +6 more
wiley   +1 more source

DART: Distilling Autoregressive Reasoning to Silent Thought [PDF]

open access: yesarXiv
Chain-of-Thought (CoT) reasoning has significantly advanced Large Language Models (LLMs) in solving complex tasks. However, its autoregressive paradigm leads to significant computational overhead, hindering its deployment in latency-sensitive applications.
arxiv  

Complement System, a Target for Therapy in Spinal Cord Injury [PDF]

open access: yes, 2016
The complement system is well known as a means of host defense but its excessive or prolonged activation can be counterproductive. Evidence points towards a dual role of complement in mediating spinal cord injury (SCI), however, the precise mechanism of ...
Narang, Aarti
core   +1 more source

Novel Biologically Active Glass Fiber Functionalized Using Magnesium Phosphate Cement Promotes Bone and Vascular Regeneration

open access: yesAdvanced Biology, EarlyView.
In this study, a new type of bioactive glass fiber ‐based composite magnesium phosphate bone cement is prepared and verified that its mechanical strength and biological properties. In addition, the cement may have played a biologically active role in the Notch and HIF signaling pathways.
Yuzheng Lu   +12 more
wiley   +1 more source

Consolidate Overview of Ribonucleic Acid Molecular Dynamics: From Molecular Movements to Material Innovations

open access: yesAdvanced Engineering Materials, EarlyView.
Molecular dynamics simulations are advancing the study of ribonucleic acid (RNA) and RNA‐conjugated molecules. These developments include improvements in force fields, long‐timescale dynamics, and coarse‐grained models, addressing limitations and refining methods.
Kanchan Yadav, Iksoo Jang, Jong Bum Lee
wiley   +1 more source

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