Results 241 to 250 of about 382,720 (316)
Absence of functional alternative complement pathway alleviates lupus cerebritis [PDF]
Jessy J. Alexander+5 more
openalex +1 more source
Fast‐relaxation viscoelastic hydrogel triggers a metabolic shift in macrophages, favoring oxidative phosphorylation (OXPHOS) over glycolysis via vasodilator‐stimulated phosphoprotein (VASP) / hypoxia‐inducible factor 1 alpha (HIF1α) signaling meditated mechanotransdution, thereby enhancing their capacity to recruit mesenchymal stem cells (MSCs) and ...
Dihao Tao+9 more
wiley +1 more source
9. Adenovirus Vector Induced Immune Responses Are Dependent upon Multi-Faceted Interactions with Proteins of Both the Alternative and Classical Complement Pathways In Vivo [PDF]
openalex +1 more source
A wireless cortical surface implant employing graphene electrode arrays diagnoses and alleviates Parkinson's disease symptoms in freely moving animals. The device continuously monitors cortical activity and delivers targeted stimulation, restoring beta–gamma and delta oscillations.
Hongseong Shin+15 more
wiley +1 more source
Nano‐Topography Enhanced Topological‐Cell‐Analysis in Radiation‐Therapy
Radiotherapy, a treatment that implies exposition of cells to radiation, offers promise to treat cancer. Here, it is hypothesized that the nanoscale details of a scaffold can amplify the response of cells to radiation, measured through topological variables, providing ways to assess the efficacy of Radiotherapy treatment.
Francesca Pagliari+8 more
wiley +1 more source
Kidney Diseases Associated With Alternative Complement Pathway Dysregulation and Potential Treatment Options. [PDF]
Sanghera P+4 more
europepmc +1 more source
This study develops itaconate‐based polymer microparticles (IA‐MPs) for macrophage‐targeted intracellular delivery, overcoming the limitations of traditional itaconate administration. IA‐MPs achieve controlled release through phagocytosis, reducing pro‐inflammatory cytokine expression and reprogramming macrophage metabolism toward glycolysis.
Kaitlyn E. Woodworth+10 more
wiley +1 more source
Rapid Activation of the Alternative Pathway of Complement by Extracorporeal Membrane Oxygenation
Heather Vallhonrat+7 more
openalex +1 more source
The limitations of existing clinical treatments highlight the need for a more comprehensive strategy for addressing infected diabetic wounds. A tri‐layered scaffold is developed to deliver therapeutics loaded in CuBDC and ZIF‐8 MOFs that are tailored to the requirements of deep‐infected diabetic wounds.
Ayse Gunyakti Mujtaba+8 more
wiley +1 more source
Editorial: The Role of Complement in Health and Disease
Maciej Cedzyński+6 more
doaj +1 more source