Results 61 to 70 of about 433,637 (362)
Human complement factor H. Two factor H proteins are derived from alternatively spliced transcripts [PDF]
, 1991 The human complement factor H is an important component in the control of the alternative pathway of complement activation. We have previously shown that at least three factor H homologous mRNA species of 4.3 kb, 1.8 kb and 1.4 kb in length are ...
Alsenz +23 more
core +1 more source
Electronic transport in single-helical protein molecules: Effects of multiple charge conduction pathways and helical symmetry [PDF]
Physics Letters A 380, 2395 (2016), 2016 We propose a tight-binding model to investigate electronic transport properties of single helical protein molecules incorporating both the helical symmetry and the possibility of multiple charge transfer pathways. Our study reveals that due to existence of both the multiple charge transfer pathways and helical symmetry, the transport properties are ...
arxiv +1 more source
Frontiers in Immunology, 2023 Properdin acts as an essential positive regulator of the alternative pathway of complement by stabilizing enzymatic convertases. Identical properdin monomers form head-to-tail associations of oligomers in a reported 20:54:26 ratio (most often described ...
Sara R. Moore +5 more
doaj +1 more source
A machine learning approach to investigate regulatory control circuits in bacterial metabolic pathways [PDF]
, 2020 In this work, a machine learning approach for identifying the multi-omics metabolic regulatory control circuits inside the pathways is described. Therefore, the identification of bacterial metabolic pathways that are more regulated than others in term of their multi-omics follows from the analysis of these circuits .
arxiv +1 more source
Activation of the alternative complement pathway by Histoplasma capsulatum [PDF]
Infection and Immunity, 1980 The present study was performed to determine whether Histoplasma capsulatum (yeast phase) is able to activate the alternative complement pathway. H. capsulatum yeasts were shown to consume C3 in C4-deficient guinea pig serum. Immunoelectrophoretic conversion of alternative pathway component factor B confirmed that C3 consumption was mediated by ...
J M Pepple, J A Winkelstein, W D Ratnoff
openaire +3 more sources
Alternative pathway activation of complement by cultured human proximal tubular epithelial cells [PDF]
, 1994 Alternative pathway activation of complement by cultured human proximal tubular epithelial cells. Human proximal tubular epithelial cells (PTEC) incubated with normal human serum (NHS) were found to fix on their surface C3, properdin, terminal complement
Biancone, Luigi +5 more
core +1 more source
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source
Essential twisted surfaces in alternating link complements [PDF]
Algebr. Geom. Topol. 16 (2016) 3209-3270, 2014 Checkerboard surfaces in alternating link complements are used frequently to determine information about the link. However, when many crossings are added to a single twist region of a link diagram, the geometry of the link complement stabilizes (approaches a geometric limit), but a corresponding checkerboard surface increases in complexity with ...
arxiv +1 more source
Blood protein adsorption onto chitosan [PDF]
, 2002 Chitosan was recently indicated to enhance osteogenesis, improve wound healing but to activate the coagulation and the complement systems. In the present study approximately 10nm thick chitosan film were prepared on aminopropyltriethoxysilane (APTES ...
Benesch, Johan, Tengvall, P.
core +1 more source
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source