Results 121 to 130 of about 2,301,526 (265)

When Do We Use Alternative Methods? Examination of the Factors Affecting the Use of Alternative Methods in Cochlear Implantation Surgery. [PDF]

J Clin Med
Öncül EC, Olgun Y, Apaydın C, Savaş Ö, Özgür E, Türkmenoğlu EB, Güneri EA.   +6 more
europepmc   +1 more source

Alternative Methods for Therapeutic Drug Monitoring and Dose Adjustment of Tuberculosis Treatment in Clinical Settings: A Systematic Review. [PDF]

Clin Pharmacokinet, 2023
Rao PS, Modi N, Nguyen NT, Vu DH, Xie YL, Gandhi M, Gerona R, Metcalfe J, Heysell SK, Alffenaar JC.   +9 more
europepmc   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Alternative methods for developmental toxicity testing: features, status and future directions. [PDF]

J Vet Sci
Hwang I, Jeung EB.
europepmc   +1 more source

A Review on Alternative Methods to Experimental Animals in Biological Testing: Recent Advancement and Current Strategies.

J Pharm Bioallied Sci, 2023
Husain A, Meenakshi DU, Ahmad A, Shrivastava N, Khan SA.   +4 more
europepmc   +1 more source

Alternative methods for RuBisCO extraction from sugar beet waste: A comparative approach of ultrasound and high voltage electrical discharge. [PDF]

Ultrason Sonochem, 2023
Dukić J, Košpić K, Kelava V, Mavrić R, Nutrizio M, Balen B, Butorac A, Halil Öztop M, Režek Jambrak A.   +8 more
europepmc   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Self-administered complementary and alternative methods of treating mental disorders among students in Wrocław: a cross-sectional study. [PDF]

Front Public Health
Sobieraj J, Sleziak J, Szyszka M, Błażejewska M, Łukańko K, Soczomska P, Bodziony K, Piotrowski P.   +7 more
europepmc   +1 more source

High-frequency ultrasound processes as alternative methods for degrading meropenem antibiotic in water. [PDF]

MethodsX, 2022
Celis-Llamoca K, Serna-Galvis EA, Torres-Palma RA, Nieto-Juárez JI.   +3 more
europepmc   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source