Results 81 to 90 of about 1,689,260 (355)

An alternative cytokinin biosynthesis pathway [PDF]

Proceedings of the National Academy of Sciences, 2000
Studies of de novo cytokinin biosynthesis in isopentenyltransferase ( ipt )-transformed Arabidopsis thaliana , involving in vivo deuterium labeling and mass spectrometry, showed that the biosynthetic rate of zeatinriboside-5′-monophosphate was
C, Astot, K, Dolezal, A, Nordström, Q, Wang, T, Kunkel, T, Moritz, N H, Chua, G, Sandberg   +7 more
openaire   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Assessment of the Role of C3(H2O) in the Alternative Pathway

Frontiers in Immunology, 2020
In this study we investigate the hydrolysis of C3 to C3(H2O) and its ability to initiate activation via the alternative pathway (AP) of the complement system.
Karin Fromell, Anna Adler, Amanda Åman, Vivek Anand Manivel, Shan Huang, Claudia Dührkop, Kerstin Sandholm, Kristina N. Ekdahl, Kristina N. Ekdahl, Bo Nilsson   +9 more
doaj   +1 more source

A Bio-Inspired Two-Layer Mixed-Signal Flexible Programmable Chip for Early Vision [PDF]

, 2003
A bio-inspired model for an analog programmable array processor (APAP), based on studies on the vertebrate retina, has permitted the realization of complex programmable spatio-temporal dynamics in VLSI.
Carmona Galán, Ricardo, Domínguez Castro, Rafael, Espejo Meana, Servando Carlos, Jiménez Garrido, Francisco José, Petrás, István, Rekeczky, Csaba, Rodríguez Vázquez, Ángel Benito, Roska, Tamás   +7 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Probing the role of a non-thermal plasma (NTP) in the hybrid NTP catalytic oxidation of methane [PDF]

, 2017
Three recurring hypotheses are often used to explain the effect of non-thermal plasmas (NTPs) on NTP catalytic hybrid reactions; namely, modification or heating of the catalyst or creation of new reaction pathways by plasma-produced species. NTP-assisted
Bruggeman, Burch, Farrauto, Foix, Gallona, Guo, Harling, Huu, Jia, Jørgensen, Kim, Kim, Lee, Liu, Lyubovsky, Mizuno, Młotek, Nilsson, Nozakia, Ricard, Rivallan, Rodrigues, Snoeck, Stere, Stere, Stere, Twomey, Van Durme, Vandenbroucke, Whitehead   +29 more
core   +3 more sources

Alternate pathways of cerebroside catabolism [PDF]

Lipids, 1973
AbstractA search was made for new degradative pathways for glucosyl and galactosyl ceramides in an effort to explain the failure of these lipids to accumulate in the brains of children with Krabbe's or Gaucher's disease. Using various buffers and incubation conditions, we tested brain homogenates from 12 day old rats with the stearate‐labeled and ...
Lin, Yuh‐nan, Radin, Norman S.
openaire   +3 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Integrating biological knowledge into variable selection : an empirical Bayes approach with an application in cancer biology [PDF]

, 2012
Background: An important question in the analysis of biochemical data is that of identifying subsets of molecular variables that may jointly influence a biological response.
Bayani, Nora, Gray, Joe W., Hill, Steven M. (Mark), Kuo, Wen-Lin, Mukherjee, Sach, Neve, Richard M., Spellman, Paul T., Ziyad, Safiyyah   +7 more
core   +3 more sources