Results 101 to 110 of about 28,556 (226)
Regulation of polyadenylation site choice in plant nuclear mRNA
The polyadenylation machinery plays a critical role in the processing of pre-mRNA into mature mRNA. This process involves a large multiprotein complex that recognizes polyadenylation signals and determines the polyadenylation sites (PASs).
Wei Zeng +3 more
doaj +1 more source
Data from Alternative Cleavage and Polyadenylation during Colorectal Cancer Development
Adam R. Morris +8 more
openalex +1 more source
ABSTRACT Brassica napus is the second most important oil crop worldwide. Number of primary branches (Branch number, BN) and silique number on the main inflorescence (SMI) are key yield‐related quantitative traits. Here, we cloned a major QTL, qDB.A09, which simultaneously influences BN and SMI.
Sihao Zhang +10 more
wiley +1 more source
Global Patterns of Tissue-Specific Alternative Polyadenylation in Drosophila [PDF]
Peter Smibert +16 more
openalex +1 more source
A new signature based on alternative polyadenylation for prognostic prediction and therapeutic responses in low-grade glioma [PDF]
Yuzhi Wang, Yunfei Xu, Yi Zhang
openalex +1 more source
Salt Stress Adaptations in Soybean Involve Alterations in Pre‐mRNA Processing
ABSTRACT Salt stress can seriously affect plant survival. To adapt to salt stress, plants can alter gene expressions and/or pre‐mRNA processing patterns, or both. Previous studies could not comprehensively profile stress‐responsive pre‐mRNA processing patterns due to limitations in traditional sequencing technologies.
Shoudong Zhang +9 more
wiley +1 more source
Multiplexed single-cell characterization of alternative polyadenylation regulators. [PDF]
Most mammalian genes have multiple polyA sites, representing a substantial source of transcript diversity regulated by the cleavage and polyadenylation (CPA) machinery. To better understand how these proteins govern polyA site choice, we introduce CPA-Perturb-seq, a multiplexed perturbation screen dataset of 42 CPA regulators with a 3' scRNA-seq ...
Kowalski MH +9 more
europepmc +3 more sources
Genome-Wide Profiling Reveals Alternative Polyadenylation of Innate Immune-Related mRNA in Patients With COVID-19 [PDF]
Sanqi An +12 more
openalex +1 more source
Local Anesthetics in Cancer: Mechanisms and Translational Perspectives
Local anesthetics demonstrate multifaceted antitumor effects that collectively contribute to cancer suppression. Beyond canonical sodium channel blockade, these agents exert the following pharmacological actions: inhibition of tumor cell proliferation, suppression of migration and invasion, induction of proapoptotic pathways, attenuation of ...
Wan‐li Wang +4 more
wiley +1 more source

