Results 101 to 110 of about 28,556 (226)

Regulation of polyadenylation site choice in plant nuclear mRNA

open access: yesEnvironmental and Experimental Botany
The polyadenylation machinery plays a critical role in the processing of pre-mRNA into mature mRNA. This process involves a large multiprotein complex that recognizes polyadenylation signals and determines the polyadenylation sites (PASs).
Wei Zeng   +3 more
doaj   +1 more source

Data from Alternative Cleavage and Polyadenylation during Colorectal Cancer Development

open access: gold, 2023
Adam R. Morris   +8 more
openalex   +1 more source

Rare Natural SNP Activates SHOOT APICAL MERISTEM ENLARGER1 to Increase Branch Number and Silique Number on the Main Inflorescence in Brassica napus

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Brassica napus is the second most important oil crop worldwide. Number of primary branches (Branch number, BN) and silique number on the main inflorescence (SMI) are key yield‐related quantitative traits. Here, we cloned a major QTL, qDB.A09, which simultaneously influences BN and SMI.
Sihao Zhang   +10 more
wiley   +1 more source

Global Patterns of Tissue-Specific Alternative Polyadenylation in Drosophila [PDF]

open access: gold, 2013
Peter Smibert   +16 more
openalex   +1 more source

Supplementary Methods from Alternative Cleavage and Polyadenylation during Colorectal Cancer Development

open access: gold, 2023
Adam R. Morris   +8 more
openalex   +1 more source

Salt Stress Adaptations in Soybean Involve Alterations in Pre‐mRNA Processing

open access: yesPlant, Cell &Environment, EarlyView.
ABSTRACT Salt stress can seriously affect plant survival. To adapt to salt stress, plants can alter gene expressions and/or pre‐mRNA processing patterns, or both. Previous studies could not comprehensively profile stress‐responsive pre‐mRNA processing patterns due to limitations in traditional sequencing technologies.
Shoudong Zhang   +9 more
wiley   +1 more source

Multiplexed single-cell characterization of alternative polyadenylation regulators. [PDF]

open access: yesCell
Most mammalian genes have multiple polyA sites, representing a substantial source of transcript diversity regulated by the cleavage and polyadenylation (CPA) machinery. To better understand how these proteins govern polyA site choice, we introduce CPA-Perturb-seq, a multiplexed perturbation screen dataset of 42 CPA regulators with a 3' scRNA-seq ...
Kowalski MH   +9 more
europepmc   +3 more sources

Genome-Wide Profiling Reveals Alternative Polyadenylation of Innate Immune-Related mRNA in Patients With COVID-19 [PDF]

open access: gold, 2021
Sanqi An   +12 more
openalex   +1 more source

Local Anesthetics in Cancer: Mechanisms and Translational Perspectives

open access: yesMedComm – Oncology, Volume 5, Issue 1, March 2026.
Local anesthetics demonstrate multifaceted antitumor effects that collectively contribute to cancer suppression. Beyond canonical sodium channel blockade, these agents exert the following pharmacological actions: inhibition of tumor cell proliferation, suppression of migration and invasion, induction of proapoptotic pathways, attenuation of ...
Wan‐li Wang   +4 more
wiley   +1 more source

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