Dynamic analyses of alternative polyadenylation from RNA-seq reveal a 3′-UTR landscape across seven tumour types [PDF]
, 2014 Zheng Xia +6 more
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Additional file 2 of REPAC: analysis of alternative polyadenylation from RNA-sequencing data
, 2023 Eddie L. Imada +3 more
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Immunology, Volume 177, Issue 2, Page 299-316, February 2026.We utilised long‐read Nanopore sequencing to characterise the transcriptome of ferret cell lines stimulated with IFN‐α as well as nasal turbinates from ferrets infected with influenza A virus. We identified novel genes and isoforms and observed elongation of poly(A) tails in the ribosome and Coronavirus Disease‐19 pathways in response to IFN‐α ...
Rubaiyea Farrukee +7 more
wiley +1 more source
Global analysis of regulatory divergence in the evolution of mouse alternative polyadenylation
Molecular Systems Biology, 2016 Alternative polyadenylation (APA), which is regulated by both cis‐elements and trans‐factors, plays an important role in post‐transcriptional regulation of eukaryotic gene expression.
Mei‐Sheng Xiao +5 more
doaj +1 more source
Tissue-specific regulation of alternative polyadenylation represses expression of a neuronal ankyrin isoform in C. elegans epidermal development [PDF]
, 2017 Fei Chen, Andrew Chisholm, Yishi Jin
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Functional characterization of NRT1/PTR FAMILY transporters: looking for a needle in a haystack
New Phytologist, Volume 249, Issue 3, Page 1124-1144, February 2026.Summary NRT1/PTR FAMILY (NPF) transporters play crucial roles in plant physiology and development due to their involvement in nitrogen nutrition and their ability to transport multiple signaling molecules and metabolites. Whereas most eukaryotic and prokaryotic NPF orthologs are peptide transporters, most flowering plant NPF transport other substrates ...
Laura Morales de Los Ríos +6 more
wiley +1 more source
Advanced Science, Volume 13, Issue 5, 27 January 2026.This study unveils a novel GAA (GCN5‐ADA2‐ACL) complex that forms nuclear condensates to boost local acetyl‐CoA, facilitating histone acetylation and gene transcription in rice meristems. The research underscores the role of ADA2's disordered region in complex condensation and ACL's role in acetyl‐CoA production.
Yaping Yue +11 more
wiley +1 more source
Methodologies for Sample Multiplexing and Computational Deconvolution in Single‐Cell Sequencing
Advanced Science, Volume 13, Issue 3, 14 January 2026.Sample multiplexing offers a critical solution for boosting throughput and minimizing batch effects in single‐cell sequencing. This review navigates the latest experimental methodologies and computational deconvolution algorithms, bridging the gap between wet‐lab design and analytical success.
Yufei Gao, Weiwei Yin, Wei Hu, Wei Chen
wiley +1 more source
Genetic Basis of Alternative Polyadenylation is an Emerging Molecular Phenotype for Human Traits and Diseases [PDF]
, 2019 Lei Li +4 more
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