Results 31 to 40 of about 951,089 (243)

Pathogenic Germline PALB2 and RAD50 Variants in Patients With Relapsed Ewing Sarcoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Approximately 10% of patients with Ewing sarcoma (EwS) have pathogenic germline variants. Here, we report two cases: first, a novel germline pathogenic variant in partner and localizer of BRCA2 (PALB2) in a patient with a late EwS relapse. Its impact on homologous recombination is demonstrated, and breast cancer risk is discussed.
Molly Mack, A. Carolina Tufino, Mohd Azrin Jamalruddin, Sreya Dey, Yinghong Pan, Elina Mukherjee, Jessica D. Daley, Julia Meade, Mahmoud Aarabi, Lisa Maurer, James Cooper, Kara A. Bernstein, Kelly M. Bailey   +12 more
wiley   +1 more source

Intraoperative Collection of Ascitic Fluid With Intra‐ or Postoperative Reinfusion in Ovarian Cancer: Safety and Feasibility of a Roller Pumping Method

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Patients with ovarian cancer often present with massive ascites, leading to significant protein loss during surgical procedures. Although cell‐free concentrated ascites reinfusion therapy (CART) is used in palliative settings to mitigate protein loss, its application in intraoperative settings remains unexplored.
Yutaka Yoneoka, Tsukuru Amano, Akimasa Takahashi, Mari Deguchi, Hiroyuki Yamanaka, Yuji Tanaka, Shunichiro Tsuji, Takashi Murakami   +7 more
wiley   +1 more source

Alternative Proteins

This is the author accepted manuscript. ; ‘Alternative proteins’ is a term used describe a diverse set of foodstuffs that have been posited as potential replacements in an individual’s diet for livestock products such as meat, milk and egg. Core examples include foods in which the core ingredients are insects, plant-based replications of meat, or novel
Elif Feyza Aydar, Zehra Mertdinç, Evren Demircan, Aslı Can Karaca, Kadriye Nur Kasapoğlu, Beraat Özçelik   +5 more
openaire   +2 more sources

Plant-Based Alternatives to Meat Products

Foods
Animal proteins have been used in the formulation and production of food products for many centuries, which has mainly been attributed to their excellent functional properties.
Claire Darizu Munialo, Vahid Baeghbali, Parag Acharya   +2 more
doaj   +1 more source

Alternative splicing and protein structure evolution [PDF]

Nucleic Acids Research, 2007
Alternative splicing is thought to be one of the major sources for functional diversity in higher eukaryotes. Interestingly, when mapping splicing events onto protein structures, about half of the events affect structured and even highly conserved regions i.e. are non-trivial on the structure level.
Birzele, Fabian, Csaba, Gergely, Zimmer, Ralf   +2 more
openaire   +2 more sources

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Alternative polyadenylation and RNA-binding proteins [PDF]

Journal of Molecular Endocrinology, 2016
Our understanding of the extent of microRNA-based gene regulation has expanded in an impressive pace over the past decade. Now, we are beginning to better appreciate the role of 3′-UTR (untranslated region) cis-elements which harbor not only microRNA but also RNA-binding protein (RBP) binding sites that have significant effect on the stability and ...
openaire   +3 more sources

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

The use of alternative protein sources in quail diets: A review

Пищевые системы
The growth of the Earth’s population and people’s striving for healthy life style lead to an increase in the global demand for protein food. Quails are a valuable source of protein, which is thought to reduce the risk of obesity and cardiovascular ...
M. A. Polubesova, E. V. Mechtaeva, A. D. Chernov, V. Yu. Sitnov, A. Z. Zhuravleva   +4 more
doaj   +1 more source

Innovations in agro-industrial production as a driver of increasing the resilience of national food systems

RUDN Journal of Economics, 2021
The destabilization of the world food market, as well as the frequent interruptions in the supply of agricultural raw materials and food products due to the global coronavirus pandemic, have catalyzed the growing interest of the overwhelming majority of ...
Vera A. Tikhomirova
doaj   +1 more source