Results 101 to 110 of about 9,355,841 (357)

Plasma Homocysteine as a Risk Factor for Dementia and Alzheimer's Disease

, 2002
Background In cross-sectional studies, elevated plasma homocysteine levels have been associated with poor cognition and dementia. Studies of newly diagnosed dementia are required in order to establish whether the elevated homocysteine levels precede the ...
S. Seshadri, A. Beiser, J. Selhub, P. Jacques, I. Rosenberg, R. D'Agostino, P. Wilson, P. Wolf   +7 more
semanticscholar   +1 more source

Aging on Chip: Harnessing the Potential of Microfluidic Technologies in Aging and Rejuvenation Research

Advanced Healthcare Materials, EarlyView.
This review highlights recent advances in microfluidic technologies for modeling human aging and age‐related diseases. It explores how organ‐on‐chip platforms improve physiological relevance, enable rejuvenation strategies, facilitate drug screening, detect senescent cells, and identify biomarkers.
Limor Zwi‐Dantsis, Vignesh Jayarajan, George M. Church, Roger D. Kamm, João Pedro de Magalhães, Emad Moeendarbary   +5 more
wiley   +1 more source

Graph theoretical analysis of magnetoencephalographic functional connectivity in Alzheimer's disease.

Brain : a journal of neurology, 2009
In this study we examined changes in the large-scale structure of resting-state brain networks in patients with Alzheimer's disease compared with non-demented controls, using concepts from graph theory.
R. Helmich, M. Hallett, G. Deuschl, I. Toni, B. Bloem, N. Granger, H. Blamires, R. J. M. Franklin, N. D. Jeffery, V. Failli, M. A. Kopp, C. Gericke, P. Martus, S. Klingbeil, B. Brommer, I. Laginha, Y. Chen, M. DeVivo, U. Dirnagl, J. M. Schwab, M. Sashindranath, E. Sales, M. Daglas, R. Freeman, A. L. Samson, E. Cops, S. Beckham, A. Galle, C. Mclean, C. Morganti-Kossmann, J. V. Rosenfeld, R. Madani, J. Vassalli, Enming J Su, D. A. Lawrence, R. Medcalf, M. Starkey, C. Bleul, B. Zörner, N. T. Lindau, T. Mueggler, M. Rudin, M. Schwab, T. Doeppner, I. Młynarczuk-Biały, U. Kuckelkorn, B. Kaltwasser, J. Herz, M. R. Hasan, D. Hermann, M. Bähr, H. Sakata, P. Narasimhan, K. Niizuma, C. Maier, T. Wakai, P. H. Chan, M. M. Helmy, E. Ruusuvuori, P. V. Watkins, J. Voipio, P. Kanold, K. Kaila, E. Butti, M. Bacigaluppi, S. Rossi, M. Cambiaghi, M. Bari, A. C. Silla, E. Brambilla, A. Musella, R. de Ceglia, L. Teneud, V. De Chiara, P. D 'adamo, J. García-Verdugo, G. Comi, L. Muzio, A. Quattrini, L. Leocani, M. Maccarrone, D. Centonze, G. Martino, K. Sathe, W. Maetzler, J. D. Lang, R. B. Mounsey, C. Fleckenstein, H. L. Martin, C. Schulte, S. Mustafa, M. Synofzik, Z. Vukovic, S. Itohara, D. Berg, P. Teismann, C. Scherfler, K. Seppi, K. J. Mair, E. Donnemiller, I. Virgolini, G. Wenning, W. Poewe, L. Tönges, T. Frank, L. Tatenhorst, K. Saal, J. Koch, É. Szegõ, Jochen H Weishaupt, P. Lingor, J. Kończak, A. Sciutti, L. Avanzino, V. Squeri, M. Gori, L. Masia, G. Abbruzzese, G. Sandini, H. Tsuji, T. Arai, F. Kametani, T. Nonaka, M. Yamashita, M. Suzukake, M. Hosokawa, M. Yoshida, H. Hatsuta, M. Takao, Y. Saito, S. Murayama, H. Akiyama, M. Hasegawa, D. M. A. Mann, A. Tamaoka, D. S. Pitceathly, C. Smith, C. Fratter, C. Alston, L. He, K. Craig, E. Blakely, J. Evans, J. Taylor, Z. Shabbir, M. Deschauer, U. Pohl, M. Roberts, M. C. Jackson, C. Halfpenny, P. Turnpenny, P. W. Lunt, M. Hanna, A. Schaefer, R. Mcfarland, R. Horvath, P. Chinnery, D. Turnbull, J. Poulton, R. Taylor, G. Gorman, D. Ronchi, C. Garone, A. Bordoni, P. G. Rios, S. E. Calvo, M. Ripolone, M. Ranieri, M. Rizzuti, L. Villa, F. Magri, S. Corti, N. Bresolin, V. Mootha, M. Moggio, S. Dimauro, G. Comi, M. Sciacco, D. Cazzoli, R. Müri, R. Schumacher, S. von Arx, S. Chaves, K. Gutbrod, S. Bohlhalter, D. Bauer, T. Vanbellingen, M. Bertschi, S. Kipfer, C. R. Rosenthal, C. Kennard, C. Bassetti, T. Nyffeler, Brain   +193 more
semanticscholar   +1 more source

Immunomodulation With Local, Sustained Delivery of Pituitary Adenylate Cyclase Activating Polypeptide Results in Improved Functional Recovery in Stroke‐Injured Mice

Advanced Healthcare Materials, EarlyView.
The tissue and functional benefits are demonstrated with local, sustained delivery of an anti‐inflammatory peptide, pituitary adenylate cyclase‐activating polypeptide (PACAP), for stroke treatment in a mouse model. Prolonged PACAP treatment modulated astrocyte and microglia toward pro‐reparative phenotypes, enhanced neuroprotection and preservation of ...
Eric Ho, David Xinzheyang Li, Hong Cui, Dania Akbar, Ricky Siu, Cindi M. Morshead, David Chatenet, Molly S. Shoichet   +7 more
wiley   +1 more source

Impact of Nanoparticle Stiffness on Endosomal Escape and Signaling Pathways in Cytosolic Delivery

Advanced Healthcare Materials, EarlyView.
Nanoparticle (NP) stiffness affects cellular uptake, but its impact on intracellular distribution remains unclear. This study synthesizes silica nanocapsules with varying stiffness, inspired by viral mechanisms, and applies assays to measure cellular uptake and escape efficiency.
Yali Zhang, Yue Hui, Zichao Guo, Dawei Liu, Yun Liu, Huajian Gao, Chun‐Xia Zhao   +6 more
wiley   +1 more source

ALZHEIMER'S DISEASE AND RELATED CONDITIONS [PDF]

, 1972
J. A. Simpson
openalex   +1 more source

State‐of‐the‐Art, Insights, and Perspectives for MOFs‐Nanocomposites and MOF‐Derived (Nano)Materials

Advanced Materials, EarlyView.
Different approaches to MOF‐NP composite formation, such as ship‐in‐a‐bottle, bottle‐around‐the‐ship and in situ one‐step synthesis, are used. Owing to synergistic effects, the advantageous features of the components of the composites are beneficially combined, and their individual drawbacks are mitigated.
Stefanos Mourdikoudis, Subhajit Dutta, Saqib Kamal, Sergio Gómez‐Graña, Isabel Pastoriza‐Santos, Stefan Wuttke, Lakshminarayana Polavarapu   +6 more
wiley   +1 more source

Advances in Photonic Materials and Integrated Devices for Smart and Digital Healthcare: Bridging the Gap Between Materials and Systems

Advanced Materials, EarlyView.
This article summarizes significant technological advancements in materials, photonic devices, and bio‐interfaced systems, which demonstrate successful applications for impacting human healthcare via improved therapies, advanced diagnostics, and on‐skin health monitoring.
Seunghyeb Ban, Hoon Yi, Jaejin Park, Yunuo Huang, Ki Jun Yu, Woon‐Hong Yeo   +5 more
wiley   +1 more source

Laminar and regional distributions of neurofibrillary tangles and neuritic plaques in Alzheimer's disease: a quantitative study of visual and auditory cortices [PDF]

, 1987
David A. Lewis, Michael J. Campbell, R. D. Terry, JH Morrison   +3 more
openalex   +1 more source

Harnessing Photo‐Energy Conversion in Nanomaterials for Precision Theranostics

Advanced Materials, EarlyView.
Harnessing photo‐energy conversion in nanomaterials enables precision theranostics through light‐driven mechanisms such as photoluminescence, photothermal, photoelectric, photoacoustic, photo‐triggered surface‐enhanced Raman scattering (SERS), and photodynamic processes. This review explores six fundamental principles of photo‐energy conversion, recent
Jingyu Shi, Yadi Fan, Qin Zhang, Yingying Huang, Mo Yang   +4 more
wiley   +1 more source