Results 61 to 70 of about 277,634 (194)
, 2016 Additional file 1. The approval Letter from Taipei City Hospital Institutional Review Board.
Shun-Ku Lin +3 more
openaire +1 more source
Validation study of “Santé-Cerveau”, a digital tool for early cognitive changes identification
Alzheimer’s Research & Therapy, 2023 Background There is a need for a reliable, easy-to-use, widely available, and validated tool for timely cognitive impairment identification. We created a computerized cognitive screening tool (Santé-Cerveau digital tool (SCD-T)) including validated ...
Constance Lesoil +12 more
doaj +1 more source
DomainScope: A disease network based on protein domain connections [PDF]
arXiv, 2019 Protein domains are highly conserved functional units of proteins. Because they carry functionally significant information, the majority of the coding disease variants are located on domains. Additionally, domains are specific units of the proteins that can be targeted for drug delivery purposes.
arxiv
, 2017 Cost-effectiveness of cerebrospinal biomarkers for Alzheimerâ s diagnosis: supplemental Methods, Results, figures and tables as referenced in the text. (DOCX 91 kb)
Lee, Spencer +3 more
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G-protein coupled estrogen receptor 1, amyloid-β, and tau tangles in older adults
Communications BiologyAccumulation of amyloid-β (Aβ) and tau tangles are hallmarks of Alzheimer’s disease. Aβ is extracellular while tau tangles are typically intracellular, and it is unknown how these two proteinopathies are connected.
Shahram Oveisgharan +10 more
doaj +1 more source
Effects of simvastatin on white matter integrity in healthy middle‐aged adults
Annals of Clinical and Translational Neurology, 2021 Background The brain is the most cholesterol‐rich organ and myelin contains 70% of total brain cholesterol. Statins are potent cholesterol‐lowing medications used by millions of adults for prevention of vascular disease, yet the effect of statins on ...
Nicholas M. Vogt +12 more
doaj +1 more source
Correlation-based Discovery of Disease Patterns for Syndromic Surveillance [PDF]
arXiv, 2021 Early outbreak detection is a key aspect in the containment of infectious diseases, as it enables the identification and isolation of infected individuals before the disease can spread to a larger population. Instead of detecting unexpected increases of infections by monitoring confirmed cases, syndromic surveillance aims at the detection of cases with
arxiv
Drugs Induced Alzheimer’s Disease in Animal Model
Galen Medical Journal, 2017 Alzheimer’s disease (AD) can be described by characteristics like dementia, mental and cognitive dysfunctions, and memory impairment. Nowadays, with progresses of science, attempts to treat many diseases have increased. Laboratory animals help to discover new ways of treating disease.
Samira Malekzadeh +3 more
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Adipobiology of the brain: From brain diabetes to adipose Alzheimer‘s disease
Adipobiology, 2015 Accumulating evidence suggests that brain-adipose tissue bidirectional communications might be promising intervention point for cardiometabolic and neurodegenerative diseases (1). Alzheimer‘s disease (AD) is a progressive and yet incurable disorder characterized by memory loss and cognitive ability deterioration. It is the most common form of dementia,
Alexander Maucher +5 more
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Molecular Neurodegeneration, 2019 Background Soluble aggregates of oligomeric forms of tau protein (oTau) have been associated with impairment of synaptic plasticity and memory in Alzheimer’s disease.
Erica Acquarone +12 more
doaj +1 more source