Results 61 to 70 of about 400,612 (318)

Magnetoencephalography as a putative biomarker for Alzheimer's disease.

, 2011
Alzheimer’s Disease (AD) is the most common dementia in the elderly and is estimated to affect tens of millions of people worldwide. AD is believed to have a prodromal stage lasting ten or more years.
Maestu, F., Del Pozo, F., Fernandez, A., Fernández, Alberto, Eero Pekkonen, Van Dijk, Bob W., Bagic, A., Bagic, Anto, Jyrki Makela, Nazareth Castellanos, Francisco del Pozo, James T. Becker, Perales Castellanos, Nazareth, Zamrini, Edward, Zamrini, E., Ricardo Bajo, Sudre, Gustavo, van Dijk, B.W., Makela, Jyrki, Pozo Guerrero, Francisco del, Funke, Michael, Edward Zamrini, Maestú, Fernando, Riley, M., Sudre, G., Pozo, F. Del, Fernando Maestu, Becker, James T., Myles Riley, Bajo, R., Funke, M., Myles, Riley, Pekkonen, E., Bob W. van Dijk, Stam, C.J., Castellanos, N., Makela, J., Dijk, B.W. van, C. J. Stam, Becker, J.T., Pekkonen, Eero, Gustavo Sudre, Bajo Breton, Ricardo, Alberto Fernandez, Michael Funke, Anto Bagic   +45 more
core   +1 more source

Additional file 1: of Role of transient receptor potential ankyrin 1 channels in Alzheimerâ s disease

, 2016
Supplementary figures. (PDF 547Â kb)
Lee, Kuan-I, Lee, Hsueh-Te, Lin, Hui-Ching, Tsay, Huey-Jen, Tsai, Feng-Chuan, Shyue, Song-Kun, Lee, Tzong-Shyuan   +6 more
openaire   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Clinicial and cost-effectiveness of donepezil, rivastigmine and galantamine for Alzheimer's disease: a rapid and systematic review [PDF]

, 2001
Background Alzheimer’s disease is the most common cause of dementia and is characterised by an insidious onset and slow deterioration. The estimated prevalence of Alzheimer’s disease for a standard health authority (500,000 people) is about 3330. Current
A. Clegg, N. Waugh, S. De Broe, Gerard, K., Bryant, J., K. Gerard, Clegg, A. J., McIntyre, Linda, L. McIntyre, Bryant, Jackie, Gerard, Karen, Waugh, Norman, McIntyre, L., Nicholson, T., T. Nicholson, De Broe, S., Clegg, A., Waugh, N., J. Bryant   +18 more
core   +1 more source

Acid sphingomyelinase as a pathological and therapeutic target in neurological disorders: focus on Alzheimer’s disease

Experimental and Molecular Medicine
Over the past decade, numerous studies have highlighted the importance of acid sphingomyelinase (ASM) in disease treatment in humans. This enzyme functions primarily to generate ceramide, maintain the cellular membrane, and regulate cellular function ...
Byung Jo Choi, Min Hee Park, Hee Kyung Jin, Jae-sung Bae   +3 more
doaj   +1 more source

Diet moderates the effect of resting state functional connectivity on cognitive function

Scientific Reports, 2022
Past research suggests modifiable lifestyle factors impact structural and functional measures of brain health, as well as cognitive performance, but no study to date has tested the effect of diet on resting state functional connectivity (rsFC), and its ...
Alexandra M. Gaynor, Eleanna Varangis, Suhang Song, Yunglin Gazes, Diala Noofoory, Reshma S. Babukutty, Christian Habeck, Yaakov Stern, Yian Gu   +8 more
doaj   +1 more source

Relationship between afternoon napping and cognitive function in the ageing Chinese population

General Psychiatry, 2021
Background Several studies have shown that afternoon napping promotes cognitive function in the elderly; on the other hand, some studies have shown opposite results.
Wei Li, Xia Li, Shifu Xiao, Lin Sun, Han Cai, Ning Su   +5 more
doaj   +1 more source

Additional file 1: of Older patients are still under-represented in clinical trials of Alzheimerâ s disease

, 2016
Details of the search strategies. (DOCX 15 kb)
Banzi, Rita, Camaioni, Paolo, Tettamanti, Mauro, Bertele’, Vittorio, Lucca, Ugo   +4 more
openaire   +1 more source

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang, Yujie Liu, Fei Li, Xuelin Li, Lanlan Li, Jie Zhang, Yali Xu   +6 more
wiley   +1 more source

Differential gene expression analysis based on linear mixed model corrects false positive inflation for studying quantitative traits

Scientific Reports, 2023
Differential gene expression (DGE) analysis has been widely employed to identify genes expressed differentially with respect to a trait of interest using RNA sequencing (RNA-Seq) data.
Shizhen Tang, Aron S. Buchman, Yanling Wang, Denis Avey, Jishu Xu, Shinya Tasaki, David A. Bennett, Qi Zheng, Jingjing Yang   +8 more
doaj   +1 more source