Results 81 to 90 of about 668 (185)
Toward the preparation of a directed library of amatoxins containing modified prolines
, 2006 Amatoxins are bicyclic peptides found in the Amanita mushroom species; these molecules are specific inhibitors of RNA polymerase II. Crystal structure data for the amatoxin-RNA polymerase II complex suggest that the hydrogen bond between Pol II Glu882 ...
Pellicelli, Jonathan
core
Lepiota castanea mushroom growing in Turkiye does not contain phallotoxins and amatoxins [PDF]
The number of poisoning cases caused by the Lepiota genus is globally increasing. This genus has more poisonous species than the Amanita genus, and many Lepiota species can cause severe toxicity and death if ingested.
Yilmaz, Ismail +3 more
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A Case Study: What Doses of Amanita phalloides and Amatoxins Are Lethal to Humans?
, 2015 Kaya, Ertugrul/0000-0003-0081-682X; Akata, Ilgaz/0000-0002-1731-1302WOS: 000366228200006PubMed: 26453489There are few data estimating the human lethal dose of amatoxins or of the toxin level present in ingested raw poisonous mushrooms. Here, we present a
Kaya, Ertuğrul +3 more
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, 1997 LIVER transplantation is now a well-established treatment in patients with fulminant hepatic failure (FHF) due to poisoning by mushrooms containing amatoxins.’ Amatoxins are a group of chemically defined octapeptides with a molecular weight of 900 ...
G. Piccolo +7 more
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, 2020 Standard calibration curves of (a) α-amanitin, (b) β-amanitin, and (c) γ-amanitin determined by lateral flow immunoassay (LFIA). The images on the left (a-c) are the test strips.
Luisa W. Cheng (361533) +4 more
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, 1981 The inhibition constants (Ki) of DNA-dependent RNA polymerase B (or II) from calf thymus were measured for eight synthetically obtained bicyclic amanitin-like thioethers, two R-sulfoxides, and two S-sulfoxides. These Ki values were compared with those of
Götzendörfer, C. +3 more
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Applied SciencesMushroom-related intoxications pose a distinctive challenge for forensic medicine because early manifestations are non-specific, latency may be prolonged, and co-exposures can obscure the mechanism of death. This narrative review summarizes key toxic and
Miłosz Badach +11 more
doaj +1 more source
Effects of interrupting the enterohepatic circulation in amatoxin intoxications
Clinical ToxicologyInterruption of the enterohepatic circulation is regarded as an effective way to treat patients with amatoxin poisoning. Nonetheless, its effectiveness has not yet been systematically evaluated. Therefore, we performed a systematic review to investigate the role of enterohepatic circulation on patient outcome and clinical laboratory values.
Jurriaan Varekamp +6 more
openaire +3 more sources
Haemoperfusion in Amanita phalloides poisoning
, 1995 Amanita phalloides is responsible for about 90 per cent of all fatal cases of mushroom intoxication, The amatoxins, the main toxic component of these fungi, are responsible for gastro-intestinal symptoms, as well as hepatic and renal ...
MAT, Afife +8 more
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Over the past two years, I have devoted sustained research effort to the therapeutic potential of amatoxins as payloads in targeted cancer therapies. As the author of this work, amanitologist, Danny LeVan-Cicchetti, I have followed closely the notable advances that have taken place in this field between 2024 and 2026.
openaire +3 more sources