UBTD1 regulates ceramide balance and endolysosomal positioning to coordinate EGFR signaling
eLife, 2021 To adapt in an ever-changing environment, cells must integrate physical and chemical signals and translate them into biological meaningful information through complex signaling pathways.
Stéphanie Torrino +17 more
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Functionalized Protein Nanotubes Based on the Bacteriophage vB_KleM-RaK2 Tail Sheath Protein
Nanomaterials, 2021 We report on the construction of functionalized nanotubes based on tail sheath protein 041 from vB_KleM-RaK2 bacteriophage. The truncated 041 protein (041Δ200) was fused with fluorescent proteins GFP and mCherry or amidohydrolase YqfB.
Greta Labutytė +7 more
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Inhibitors of bacterial and plants urease [PDF]
, 2013 Urease is an important virulence factor for Helicobacter pylori and Proteus mirabilis as well as in environmental transformations of certain nitrogenous compounds.
Macegoniuk, Katarzyna
core +2 more sources
Crystal structure of N-carbamyl-d-amino acid amidohydrolase with a novel catalytic framework common to amidohydrolases [PDF]
Structure, 2000 N-carbamyl-D-amino acid amidohydrolase (DCase) catalyzes the hydrolysis of N-carbamyl-D-amino acids to the corresponding D-amino acids, which are useful intermediates in the preparation of beta-lactam antibiotics. To understand the catalytic mechanism of N-carbamyl-D-amino acid hydrolysis, the substrate specificity and thermostability of the enzyme, we
Nakai, T. +10 more
openaire +2 more sources
The Early Asexual Development Regulator fluG Codes for a Putative Bifunctional Enzyme
Frontiers in Microbiology, 2019 FluG is a long recognized early regulator of asexual development in Aspergillus nidulans. fluG null mutants show profuse aerial growth and no conidial production.
Mikel Iradi-Serrano +3 more
doaj +1 more source
Sated by a Zero-Calorie Sweetener: Wastewater Bacteria Can Feed on Acesulfame
Frontiers in Microbiology, 2019 The widely used artificial sweetener acesulfame K has long been considered recalcitrant in biological wastewater treatment. Due to its persistence and mobility in the aquatic environment, acesulfame has been used as marker substance for wastewater input ...
Sabine Kleinsteuber +5 more
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Amperometric biosensor based on reductive H2O2 detection using pentacyanoferrate-bound polymer for creatinine determination. [PDF]
, 2013 Pentacyanoferrate-bound poly(1-vinylimidazole) (PVI[Fe(CN)5]) was selected as a mediator for amperometric creatinine determination based on the reductive H2O2 detection.
Kano, Kenji +3 more
core +1 more source
Analgesic Effects of Fatty Acid Amide Hydrolase Inhibition in a Rat Model of Neuropathic Pain [PDF]
, 2006 Cannabinoid-based medicines have therapeutic potential for the treatment of pain. Augmentation of levels of endocannabinoids with inhibitors of fatty acid amide hydrolase (FAAH) is analgesic in models of acute and inflammatory pain states.
Barrett, David +4 more
core +2 more sources
MicrobiologyOpen, 2019 Here, we present a proof‐of‐principle for a new high‐throughput functional screening of metagenomic libraries for the selection of enzymes with different activities, predetermined by the substrate being used. By this approach, a total of 21 enzyme‐coding
Vida Časaitė +9 more
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Biochemical properties of penicillin amidohydrolase from Micrococcus luteus [PDF]
Applied and Environmental Microbiology, 1979 Some biochemical properties of whole-cell penicillin amidohydrolase from Micrococcus luteus have been studied. This whole-cell enzyme showed its maximal activity at 36 degrees C at pH 7.5. It was found that the activation energy of this enzyme was 8.03 kcal (ca. 33.6 kJ) per mol, and this amidohydrolase showed first-order decay at 36 degrees C.
D H, Nam, D D, Ryu
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