Results 61 to 70 of about 10,073 (196)

Inactivation of anandamide signaling : A continuing Debate [PDF]

, 2010
Copyright 2011 Elsevier B.V., All rights reserved.Peer reviewedPublisher ...
Ahluwalia, Ahn, Alexander, Alexander, Beltramo, Bhave, Bifulco, Bisogno, Bisogno, Bosier, Cadas, Chen, Chuang, Clapper, Cravatt, Cravatt, Cristino, Day, De Petrocellis, De Petrocellis, De Petrocellis, Desarnaud, Deutsch, Deutsch, Devane, Devane, Di Carlo, Di Marzo, Di Marzo, Di Marzo, Egertova, Evans, Evans, Evans, Fedorova, Glaser, Guzmán, Hampson, Hanus, Harizi, Hesham Khairy, Hillard, Hillard, Hillard, Horvath, Howlett, Howlett, Iversen, Jarrahian, Jiang, Jonsson, Kaczocha, Kaczocha, Katayama, Kathuria, Khairy, Klein, Koutek, Kulkarni-Narla, Liu, Long, Maccarrone, Malcher-Lopes, Matsuda, McFarland, Mechoulam, Mechoulam, Mechoulam, Mechoulam, Miller, Moore, Mulder, Munro, Numazaki, Okamoto, Ortar, Pertwee, Piomelli, Poling, Porter, Premkumar, Randall, Schlosburg, Schmid, Simon, Stella, Stremmel, Sun, Sun, Sánchez, Thomas, Thors, Tian, Tsou, Tsuboi, Ueda, Ueda, Van den Bossche, Van Der Stelt, Wael E. Houssen, Walker, Weber, Wenger, Wood, Woodward, Yu, Zygmunt   +106 more
core   +3 more sources

Methyl Jasmonate Seed Priming Mitigates the Defence‐Growth Trade‐Off and Tailors Plant Response to Specific Pests

Plant, Cell &Environment, EarlyView.
ABSTRACT Seed defence priming is emerging as a novel, cost‐efficient and environmentally safe tool for pest management. It has been proposed as a means to uncouple the defence‐growth trade‐off in plants by enhancing defence responses with minimal fitness costs, but the mechanisms underlying this role remain elusive.
Lucia Talavera‐Mateo, Adrian Sabater‐Gabriel, Alejandro Garcia, Marta Marina Perez‐Alonso, Rayko Halitschke, M. Estrella Santamaria   +5 more
wiley   +1 more source

The gut microbiome promotes the growth performance of black soldier fly larvae by detoxifying uric acid

iMetaOmics, Volume 3, Issue 1, March 2026.
This study demonstrates the detrimental effects of exogenous uric acid (UA) on the growth of black soldier fly (BSF) larvae, highlighting the role of gut microbiota in UA degradation. We isolated UA‐degrading bacterial strains associated with BSF, including Enterococcus faecalis AHAU24.
Xiaowen Ji, Shaojie Zhou, Wenwen Chen, Bin Cao, Jingjing Zhuang, Sheng Zhang, Bingshuo Han, Benping Yang, Shuxiang Zhang, Yanfeng Xue, Jibin Zhang, Yinglao Zhang, Wei Liu   +12 more
wiley   +1 more source

Deciphering Physiological Functions of AHL Quorum Quenching Acylases

Frontiers in Microbiology, 2017
N-Acylhomoserine lactone (AHL)-acylase (also known as amidase or amidohydrolase) is a class of enzyme that belongs to the Ntn-hydrolase superfamily. As the name implies, AHL-acylases are capable of hydrolysing AHLs, the most studied signaling molecules ...
Putri D. Utari, Jan Vogel, Wim J. Quax
doaj   +1 more source

SECONDARY EFFECT OF 8-AZAGUANINE ON THE INDUCED OR CONSTITUTIVE SYNTHESIS OF PENICILLINASE IN BACILLUS CEREUS. EUR 509.e [PDF]

, 1963
1. 1. During the restoration of protein synthesis caused by guanosine after inhibition by azaguanine, the differential rate of synthesis of penicillinase (penicillin amidohydrolase, EC 3.5.2.6) is much reduced. 2. 2.
Chantrenne, H., Leclercq-Calingaert, M.
core   +1 more source

Characterization of the gene cluster involved in allantoate catabolism and its transcriptional regulation by the RpiR-type repressor HpxU in Klebsiella pneumoniae [PDF]

, 2013
Bacteria, fungi, and plants have metabolic pathways for the utilization of nitrogen present in purine bases. In Klebsiella pneumoniae, the genes responsible for the assimilation of purine ring nitrogen are distributed in three separated clusters.
Evangelina Campos, Josefa Badia, Juan Aguilar, Karla Guzmán, Laura Aguilera, Laura Baldoma, Lorena Toloza, Rosa Giménez   +7 more
core   +1 more source

A sulfoximine-based inhibitor of human asparagine synthetase kills l-asparaginase-resistant leukemia cells. [PDF]

, 2012
An adenylated sulfoximine transition-state analogue 1, which inhibits human asparagine synthetase (hASNS) with nanomolar potency, has been reported to suppress the proliferation of an l-asparagine amidohydrolase (ASNase)-resistant MOLT-4 leukemia cell ...
Ahn, Yong-Mo, Hegazy, Lamees, Hiratake, Jun, Ikeuchi, Hideyuki, Otokawa, Takuya, Richards, Nigel G J, Watanabe, Bunta   +6 more
core   +1 more source

Thermotolerant D‐Hydantoinases for Efficient and Stereoselective Intermediate Synthesis of (R)‐3‐Isobutylglutaric Acid Monoamide, a Key Intermediate in Pregabalin Production

Microbial Biotechnology, Volume 19, Issue 3, March 2026.
We engineered thermo‐alkali‐stable D‐hydantoinases via mutagenesis (M63A/F65H/C317T) to resolve Pregabalin's challenging chiral splitting, achieving ee value > 97% for key intermediate (R)‐3‐isobutylglutaric acid monoamide (R‐IBM) synthesis under extreme conditions (pH 10, 70°C–80°C).
Jiujiuzi Zhang, Bin Zhi, Zhenyu Xie, Beibei Zhang, Ning Wang, Wanpeng Wang   +5 more
wiley   +1 more source

Structural Analyses on the Deamidation of N-Terminal Asn in the Human N-Degron Pathway

Biomolecules, 2020
The N-degron pathway is a proteolytic system in which a single N-terminal amino acid acts as a determinant of protein degradation. Especially, degradation signaling of N-terminal asparagine (Nt-Asn) in eukaryotes is initiated from its deamidation by N ...
Joon Sung Park, Jae-Young Lee, Yen Thi Kim Nguyen, Nae-Won Kang, Eun Kyung Oh, Dong Man Jang, Hyun-Jung Kim, Dae-Duk Kim, Byung Woo Han   +8 more
doaj   +1 more source

Molecular cloning and characterization of an amidase from Arabidopsis thaliana capable of converting indole-3-acetamide into the plant growth hormone, indole-3-acetic acid [PDF]

, 2003
Acylamidohydrolases from higher plants have not been characterized or cloned so far. AtAMI1 is the first member of this enzyme family from a higher plant and was identified in the genome of Arabidopsis thaliana based on sequence homology with the ...
Andersson, Ausubel, Bar, Barkan, Bartel, Bradford, Chou, Cravatt, Daniel Neu, Davies, Eckhardt, Elmar W Weiler, Hillebrand, Igoshi, Kawaguchi, Kawaguchi, Klee, Klee, Kobayashi, Kobayashi, Kobayashi, Laemmli, LeClere, Magie, Manulis, McKinney, Sambrook, Saotome, Scharf, Schägger, Stephan Pollmann, Takahashi, Towbin, Vorwerk, Weiler, Yamada, Östin   +36 more
core   +2 more sources