Results 81 to 90 of about 10,587 (231)

A picorna-like virus suppresses the N-end rule pathway to inhibit apoptosis

eLife, 2017
The N-end rule pathway is an evolutionarily conserved proteolytic system that degrades proteins containing N-terminal degradation signals called N-degrons, and has emerged as a key regulator of various processes.
Zhaowei Wang, Xiaoling Xia, Xueli Yang, Xueyi Zhang, Yongxiang Liu, Di Wu, Yuan Fang, Yujie Liu, Jiuyue Xu, Yang Qiu, Xi Zhou   +10 more
doaj   +1 more source

SECONDARY EFFECT OF 8-AZAGUANINE ON THE INDUCED OR CONSTITUTIVE SYNTHESIS OF PENICILLINASE IN BACILLUS CEREUS. EUR 509.e [PDF]

, 1963
1. 1. During the restoration of protein synthesis caused by guanosine after inhibition by azaguanine, the differential rate of synthesis of penicillinase (penicillin amidohydrolase, EC 3.5.2.6) is much reduced. 2. 2.
Chantrenne, H., Leclercq-Calingaert, M.
core   +1 more source

Exploring the Critical Environmental Optima and Biotechnological Prospects of Fungal Fruiting Bodies

Microbial Biotechnology, Volume 18, Issue 8, August 2025.
Mechanisms and strategies for fungal fruiting body development (FBD) are reported. The critical optima for the relevant environmental cues regulating FBD were synthesised. Fruiting body biotechnological applications and recent advances in designed approaches are elucidated.
Amechi S. Nwankwegu, Sinang Hongsanan, Uzoma P. Nwankwegu, Ning Xie   +3 more
wiley   +1 more source

A NIR fluorescent probe for Vanin-1 and its applications in imaging, kidney injury diagnosis, and the development of inhibitor

Acta Pharmaceutica Sinica B, 2022
Vanin-1 is an amidohydrolase that catalyses the conversion of pantetheine into the amino-thiol cysteamine and pantothenic acid (coenzyme A precursor), which plays a vital role in multiple physiological and pathological processes. In this study, an enzyme-
Zhenhao Tian, Fei Yan, Xiangge Tian, Lei Feng, Jingnan Cui, Sa Deng, Baojing Zhang, Tian Xie, Shanshan Huang, Xiaochi Ma   +9 more
doaj   +1 more source

Subcellular localization and tissue specific expression of amidase 1 from Arabidopsis thaliana [PDF]

, 2006
Amidase 1 (AMI1) from Arabidopsis thaliana converts indole-3-acetamide (IAM), into indole-3-acetic acid (IAA). AMI1 is part of a small isogene family comprising seven members in A.
A Müller, A Müller, A Vojta, A Wachter, AM Metz, AW Woodward, BA Stelmach, BF Cravatt, Daniel Neu, DE Saslowsky, DK Giang, E Kemper, Elmar W. Weiler, EW Weiler, FA Ausubel, H Towbin, J Haseloff, J Sambrook, J-F Mayaux, JJ Finer, K Sohrt, KD Scharf, M Kawaguchi, M Kawaguchi, M Kobayashi, M Madera, M Saotome, MH Bracey, MM Bradford, MP Patricelli, NM Upadhyaya, NR Hofmann, O Chew, O Kleiner, Oliver Berkowitz, R Shrestha, R Shrestha, S Brenner, S Pollmann, S Pollmann, S Shin, S Shin, S Vorwerk, SR Cutler, Stephan Pollmann, T Murashige, Thomas Lehmann, Tina Schäfer, VS Reddy, WB Bruce, Y Arai, YJ Lee, YQ An, YS Kim   +53 more
core   +2 more sources

Update: Enzymatische Synthese für industrielle Anwendungen

Angewandte Chemie, Volume 137, Issue 27, July 1, 2025.
Die Biokatalyse hat sich zu einer nachhaltigen und wettbewerbsfähigen Alternative zur herkömmlichen chemischen Synthese entwickelt und ermöglicht die enzymbasierte Herstellung nicht nur von chemischen Grundstoffen, sondern auch von (nicht natürlichen) Aminosäuren, (seltenen) Zuckern und synthetischen Nukleotiden.
Thomas Bayer, Shuke Wu, Radka Snajdrova, Kai Baldenius, Uwe T. Bornscheuer   +4 more
wiley   +1 more source

Creatinine biosensors: principles and designs [PDF]

, 2000
Creatinine biosensors, based on both potentiometric and amperometric devices, have been created. However, there are significant problems still to be addressed, including the balance between sensitivity and selectivity, interference rejection and sensor
Killard, Anthony J., Smyth, Malcolm R.
core   +1 more source

An Update: Enzymatic Synthesis for Industrial Applications

Angewandte Chemie International Edition, Volume 64, Issue 27, July 1, 2025.
Biocatalysis has become a sustainable and cost‐competitive alternative to established chemical synthesis, enabling the enzyme‐based production of not only commodity chemicals but (non‐natural) amino acids, (rare) sugars, as well as synthetic nucleotides.
Thomas Bayer, Shuke Wu, Radka Snajdrova, Kai Baldenius, Uwe T. Bornscheuer   +4 more
wiley   +1 more source

Structural Analyses on the Deamidation of N-Terminal Asn in the Human N-Degron Pathway

Biomolecules, 2020
The N-degron pathway is a proteolytic system in which a single N-terminal amino acid acts as a determinant of protein degradation. Especially, degradation signaling of N-terminal asparagine (Nt-Asn) in eukaryotes is initiated from its deamidation by N ...
Joon Sung Park, Jae-Young Lee, Yen Thi Kim Nguyen, Nae-Won Kang, Eun Kyung Oh, Dong Man Jang, Hyun-Jung Kim, Dae-Duk Kim, Byung Woo Han   +8 more
doaj   +1 more source

Thermodynamics of ligand binding to histone deacetylase like amidohydrolase from Bordetella/Alcaligenes [PDF]

, 2014
Thermodynamic studies on ligand–protein binding have become increasingly important in the process of drug design. In combination with structural data and molecular dynamics simulations, thermodynamic studies provide relevant information about the mode of
Baud, Matthias, Fuchter, Matthew J., Meyer-Almes, Franz-Josef, Meyners, Christian   +3 more
core   +1 more source