Results 41 to 50 of about 7,986,817 (400)
Molbank, 2010 A luminescent aza-27-crown-9 ether amino acid was prepared by a three-step reaction sequence. The compound signals ammonium ion binding by an increase in emission intensity.
Andreas Späth, Burkhard König
doaj +1 more source
An Alternative Model of Amino Acid Replacement [PDF]
, 2004 The observed correlations between pairs of homologous protein sequences are typically explained in terms of a Markovian dynamic of amino acid substitution.
Altschul +27 more
core +2 more sources
Predicting deleterious amino acid substitutions.
Genome Research, 2001 Many missense substitutions are identified in single nucleotide polymorphism (SNP) data and large-scale random mutagenesis projects. Each amino acid substitution potentially affects protein function. We have constructed a tool that uses sequence homology
P. Ng, S. Henikoff
semanticscholar +1 more source
An improved general amino acid replacement matrix.
Molecular biology and evolution, 2008 Amino acid replacement matrices are an essential basis of protein phylogenetics. They are used to compute substitution probabilities along phylogeny branches and thus the likelihood of the data. They are also essential in protein alignment.
S. Le, O. Gascuel
semanticscholar +1 more source
Amino Acid Metabolism in Lupus
Frontiers in Immunology, 2021 T cell metabolism is central to cell proliferation, survival, differentiation, and aberrations have been linked to the pathophysiology of systemic autoimmune diseases.
Michihito Kono +2 more
doaj +1 more source
Evolution of a genome-encoded bias in amino acid biosynthetic pathways is a potential indicator of amino acid dynamics in the environment. [PDF]
, 2014 Overcoming the stress of starvation is one of an organism's most challenging phenotypic responses. Those organisms that frequently survive the challenge, by virtue of their fitness, will have evolved genomes that are shaped by their specific environments.
Fasani, Rick A, Savageau, Michael A
core +1 more source
Prediction of protein antigenic determinants from amino acid sequences.
Proceedings of the National Academy of Sciences of the United States of America, 1981 A method is presented for locating protein antigenic determinants by analyzing amino acid sequences in order to find the point of greatest local hydrophilicity.
T. Hopp, K. R. Woods
semanticscholar +1 more source
Nature's Starships. I. Observed Abundances and Relative Frequencies of Amino Acids in Meteorites [PDF]
, 2014 The class of meteorites called carbonaceous chondrites are examples of material from the solar system which have been relatively unchanged from the time of their initial formation. These meteorites have been classified according to the temperatures and physical conditions of their parent planetesimals.
arxiv +1 more source
The Regulatory Role of MeAIB in Protein Metabolism and the mTOR Signaling Pathway in Porcine Enterocytes. [PDF]
, 2018 Amino acid transporters play an important role in cell growth and metabolism. MeAIB, a transporter-selective substrate, often represses the adaptive regulation of sodium-coupled neutral amino acid transporter 2 (SNAT2), which may act as a receptor and ...
Ji, Peng +5 more
core +2 more sources
A classification of glycosyl hydrolases based on amino acid sequence similarities.
Biochemical Journal, 1991 The amino acid sequences of 301 glycosyl hydrolases and related enzymes have been compared. A total of 291 sequences corresponding to 39 EC entries could be classified into 35 families.
B. Henrissat
semanticscholar +1 more source