Results 191 to 200 of about 3,092,210 (299)

Targeting β2‐Adrenergic Receptor Stability With Lycorine Reveals a Host‐Directed Pathway for Antiviral Defense Against Poxviruses

Advanced Science, EarlyView.
Chronic stress drives autophagy‐mediated β2‐AR degradation, impairing antiviral immunity and promoting poxvirus lethality. Lycorine directly stabilizes β2‐AR to restore host defense, suppress excessive inflammation and improve survival. ABSTRACT Psychological stress is a pervasive yet poorly understood modulator of infectious disease outcomes. Here, we
Xin Zhang, Shuqin Xu, Zixuan Zhang, Chenwen Wan, Xiaoqin Wang, Peihua Wang, Huini Yang, Tianxiao Huang, Yijia Yuan, Faiza Atique, Rui Yang, Yingli He, Zhijun Liu   +12 more
wiley   +1 more source

Corrigendum to "Determination and prediction of standardized ileal amino acid digestibility of wheat for pullets during the brooding and growing phases" [Poult. Sci. 2026 Mar 2;105(6):106726]. [PDF]

Poult Sci
Zhang L.
europepmc   +1 more source

The Mitogen‐Activated Protein Kinase GhNTF3 Modulates the Arbuscular Mycorrhizal Symbiosis‐Immunity Trade‐Off in Cotton by Regulating Salicylic Acid Biosynthesis

Advanced Science, EarlyView.
AM symbiosis induces GhWAK13 to promote fungal colonization. GhNTF3 negatively regulates symbiosis by promoting SA biosynthesis. GhWAK13 sequesters GhNTF3 at the membrane, limiting its nuclear translocation and relieving SA‐mediated suppression. Under Verticillium stress, GhNTF3 enters the nucleus and interacts with GhJAZ6 to activate SA signaling ...
Shuangjie Jia, Jingshang Wen, Jihang Li, Meina Feng, Yiming He, Ruojun Liu, Qian Liu, Junli Zhang, Kai Cheng, Xiangyu Zhang, Xiao Zhang   +10 more
wiley   +1 more source

Drying Temperature Dictates Ileal Amino Acid Digestibility of Enzyme-Treated Soybean Meal in 25 kg Pigs. [PDF]

Animals (Basel)
Tan X, Liu C, Lu L, Zhuo Y, Li L, Liang Y.   +5 more
europepmc   +1 more source

Dual‐Gene Edited Extracellular Vesicles Remodel the Redox Homeostasis to Inhibit Ferroptosis in Intervertebral Disc Degeneration

Advanced Science, EarlyView.
ABSTRACT Intervertebral disc degeneration (IDD) is driven by ferroptosis of nucleus pulposus cells (NPCs) as a core pathological mechanism. Nucleus pulposus progenitor cells (NPPCs), exhibiting stem cell‐like properties, yield extracellular vesicles (PEVs) with high affinity for NPCs and enable targeted phenotypic regulation.
Jing Yan, Yazhou Lin, Shuo Miao, Minghao Chao, Chengbai Dai, Ziwen Hao, Rui Chen, Ming Guan, Bin Pan, Fenglei Gao, Quan Zhou   +10 more
wiley   +1 more source

Determination and correlations of standardized ileal amino acid digestibility with chemical composition of corn in broilers at 13 and 28 days of age. [PDF]

Poult Sci
Guo X, Ning R, Cheng Z, Zhao Z, Ban Z, Guo Y, Nie W.   +6 more
europepmc   +1 more source

An Effector TaCRVP From Tuta Absoluta Oral Secretion Impairs H2O2‐Mediated Plant Defense by Targeting Tomato SlCAT2

Advanced Science, EarlyView.
The Tuta absoluta salivary effector TaCRVP subverts tomato immunity by hijacking host catalase SlCAT2. Through a sophisticated dual mechanism, TaCRVP simultaneously promotes SlCAT2 tetramerization for activation and blocks its SlAdBiL‐mediated degradation for stabilization.
Jianquan Yan, Youdan Zhang, Zhujun Wang, Huatao Tang, Huiping Liu, Zi Chen, Shuai Liu, Jiayi Shi, Lu Peng, Youming Hou   +9 more
wiley   +1 more source

Determination of the standardized ileal amino acid digestibility of corn in 13-day-old broilers and establishment of the prediction equations. [PDF]

Poult Sci
Hang Z, Wang Z, Xing T, Zhao L, Zhang L, Gao F.   +5 more
europepmc   +1 more source

An Expert Consensus Framework for a Database on Ileal Amino Acid Digestibility and Protein Quality Scoring From Foods Consumed by Humans

International audienceObjectives: Food Protein Quality is best measured by the amino acid scoring that relates their indispensable amino acid content to a reference profile after correction for digestibility.
Han, Fei, Owino, Victor, Tome, Daniel, Shertukde, Shruti, Prasad, Recio, Isidra, Calvez, Juliane, Mes, Jurriaan, Hayes, Maria, Hodgkinson, Suzanne, Courtney-Martin, Glenda, Gaudichon, Claire, C., Stein, Hans, H, Ferriolli, Eduardo, Elango, Rajavel, Xipsiti, Maria, Kurpad, Anura, Vlassopoulos, Antonios   +16 more
core  

A Synthetic Platform for Antibody Junctional Diversification Beyond Natural Constraints

Advanced Science, EarlyView.
ARESEC is a synthetic platform that reconstructs functional V(D)J recombination in HEK293T cells. By introducing RSS elements and co‐expressing RAG1/2 and TdT across all three antibody CDRs, it enables programmable junctional diversification and direct generation of high‐affinity variants targeting PD‐1/PD‐L1, overcoming the evolutionary constraints of
Wang Liu, Jun Yang, Yuhang Zhang, Xiaoli Xue   +3 more
wiley   +1 more source