Results 251 to 260 of about 63,519 (311)

Activating the Osteoblastic USP26 Pathway Alleviates Multi‐Organ Fibrosis by Decreasing Insulin Resistance

Advanced Science, EarlyView.
The loss of Ubiquitin Specific Peptidase 26 (USP26) in osteoblasts results in decreased bone formation, as well as multi‐organ fibrosis associated with insulin resistance (IR). Mechanistically, the absence of USP26 reduces glycolysis and lactate accumulation, leading to decreased histone H3 lysine 18 lactylation (H3K18LA) in the promoter region of KH ...
Jiyuan Tang, Wenkai Ye, Liang He, Zhou Dan, Leilei Chang, Zijie You, Yuanyue Jiang, Guoqing Tang, Lianfu Deng, Changwei Li   +9 more
wiley   +1 more source

Metabolizable Energy and Amino Acid Digestibility of Soybean Meal from Different Sources for Broiler Chickens Supplemented with Protease. [PDF]

Animals (Basel)
Xavier Junior ML, Ferreira RS, Teixeira LDV, Valentim JK, Gomes KM, Bernandes RD, Calderano AA, Albino LFT.   +7 more
europepmc   +1 more source

Extracellular Vesicles of Streptococcus anginosus Mediate Gastritis via Epithelial Barrier Disruption and Macrophage‐driven Inflammation

Advanced Science, EarlyView.
Streptococcus anginosus extracellular vesicles (SA‐EVs) accumulate in gastric tissue, disrupt epithelial tight junctions, and induce gastritis characterized by neutrophil infiltration and elevated cytokines (TNF‐α, IL‐6, IL‐17A). Proteomics identifies TMPC and FBP62 as key SA‐EVs virulence factors; their genetic deletion attenuates inflammation ...
Ying Gong, Lina Duan, Jie Xiao, Yulu Deng, Hongxia Wang, Yajie Zhang, Xiumei Hu, Haifang Wang, Taixue An, Xin Li, Yurong Qiu, Lei Zheng, Haixia Li   +12 more
wiley   +1 more source

Standardized amino acid digestibility and nitrogen-corrected true metabolizable energy of frozen raw, freeze-dried raw, mildly cooked, and retorted dog foods using the precision-fed cecectomized and conventional rooster assays. [PDF]

J Anim Sci
Geary EL, Vogel CL, Parsons CM, Utterback PL, Templeman JR, Danao MC, Swanson KS.   +6 more
europepmc   +1 more source

PBRM1 Deficiency Reshapes an Immune Suppressive Microenvironment Through Epigenetic Tuning of PBRM1‐KDM5C‐IL6 Axis in ccRCC

Advanced Science, EarlyView.
PBRM1 ranks as the second most commonly mutated gene in ccRCC. This study reveals that PBRM1 loss promotes an immunosuppressive microenvironment by elevating M2 TAMs via the KDM5C–IL‐6 axis. These M2 TAMs, along with CAFs, form a barrier that excludes CD8+ T cells. Targeting IL‐6 synergizes with anti‐PD1 therapy, offering a promising strategy for PBRM1‐
Wenjiao Xia, Hongru Wang, Yu Dong, Zitong Yang, Yiyang Zhou, Zhinan Xia, Qinchen Li, Liangliang Ren, Yichun Zheng, Junliang Yan, Dongmei Ma, Zhi Chen, Xingang Cui, Guixin Zhu, Cheng Zhang   +14 more
wiley   +1 more source

Autoclaving time-related reduction in amino acid digestibility of poultry meal in broiler chickens and growing pigs. [PDF]

J Anim Sci
Sung JY, Park CS, Ragland D, Caroline González-Vega J, Wiltafsky-Martin MK, Adeola O.   +5 more
europepmc   +1 more source

Cowpea (Vigna unguiculata) drilling [PDF]

, 2015
Bastianelli, Denis, Heuzé, Valérie, Lebas, François, Nozière, Pierre, Tran, Gilles   +4 more
core  

Effect of age on the standardized ileal amino acid digestibility of soybean meal and canola meal in broilers. [PDF]

Anim Nutr
Barua M, Abdollahi MR, Zaefarian F, Wester TJ, Girish CK, Chrystal PV, Ravindran V.   +6 more
europepmc   +1 more source