Results 181 to 190 of about 24,002 (247)

NADPH Dehydrogenase Gene Regulates Energy Distribution and Fatty Acid Metabolism During Fruiting Body Formation in the Filamentous Fungus Podospora anserina. [PDF]

Microb Biotechnol
Qiu Y, Nwankwegu AS, Sun Y, Li Y, Chen W, Liu G, Xie N.   +6 more
europepmc   +1 more source

Studies of interaction of homo-dimeric ferredoxin-NAD(P)+ oxidoreductases of Bacillus subtilis and Rhodopseudomonas palustris, that are closely related to thioredoxin reductases in amino acid sequence, with ferredoxins and pyridine nucleotide coenzymes

Studies of interaction of homo-dimeric ferredoxin-NAD(P)+ oxidoreductases of Bacillus subtilis and Rhodopseudomonas palustris, that are closely related to thioredoxin reductases in amino acid sequence, with ferredoxins and pyridine nucleotide coenzymes
Ferredoxin-NADP+ oxidoreductases (FNRs) of Bacillus subtilis (YumC) and Rhodopseudomonas palustris CGA009 (RPA3954) belong to a novel homo-dimeric type of FNR with high amino acid sequence homology to NADPH-thioredoxin reductases. These FNRs were purified from expression constructs in Escherichia coli cells, and their steady-state reactions with [2Fe ...
openaire  

Ferroptosis‐Based Peripheral Immune Dysregulation and Diagnostic Signatures in Parkinson's Disease: An RNA Transcriptomic and Single‐Cell Immune Sequencing Analysis

The FASEB Journal, Volume 40, Issue 15, 15 August 2026.
This study explored the crosstalk between ferroptosis‐related genes and peripheral immune alterations in Parkinson's disease. We constructed a gene signature and classified molecular subtypes, and further pinpointed key ferroptosis‐associated molecules in immune cells and neuronal cells.
Lei Cheng, Jing Zhang, Wen‐Ting Shi, Qing Ye, Chen Huang, Zhong‐Yan Zhou   +5 more
wiley   +1 more source

Evidence for ecological adaptation of reductive citric acid and reverse oxidative citric acid cycles based on a survey of genomes from autotrophic <i>Bacteria</i>. [PDF]

FEMS Microbes
Scott KM, Walsh DP, Napier L, Bohdanovska M, Conde Q, Machado-Olavarria AC, Madala S, Meade SM, Nguyen KT, Nguyen T, O'Malley D, Palmer H, Parbhoo KJ, Pfent A, Phillips R, Busato VP, Rakhmonova M, Ruiz D, Small E, Spence SS, Thakur A.   +20 more
europepmc   +1 more source

Intranasal Administration of Isoeugenol Improves Memory Deficits in APP/PS1 Old Mice—A Role Beyond Nrf2 Activation?

The FASEB Journal, Volume 40, Issue 15, 15 August 2026.
Inactivation of the Nrf2/Are pathway in AD leads to decreased antioxidant and anti‐inflammatory response and to the accumulation of beta‐amyloid (Aβ) plaques, resulting in cognitive failure. Treatment with Isoeugenol activates Nrf2, reversing these outcomes by promoting antioxidant response in neuronal cells (N2a) and by increasing the anti ...
Ana Silva, Sónia Silva, Jéssica Macedo, Patrícia Moreira, Diana Baptista, Joana Bicker, Ana Fortuna, Joana Liberal, Beatriz Rodrigues, Rosa Resende, Inês Vitorino, Armanda E. Santos, Bruno Miguel Neves, Cláudia Pereira, Maria Teresa Cruz   +14 more
wiley   +1 more source

A Lipid‐Conjugation Strategy for Intracellular Reactive Oxygen Species Control in Hepatic Cells

Angewandte Chemie, Volume 138, Issue 33, 10 August 2026.
A lipid conjugation strategy anchors a manganese Salen complex within phospholipid membranes, yielding stable, catalytically active liposomes. These lipid–metal assemblies efficiently degrade reactive oxygen species (ROS) and enable intracellular redox control in steatotic HepaRG cells, offering a precise route to biomimetic antioxidant design ...
Olav Vestrheim, Huichao Zhao, Anders Bodholt Nielsen, Nino Wili, Niels Chr. Nielsen, Joseph A. Lyons, Rajeshwar Prosad Mookerjee, Brigitte Städler   +7 more
wiley   +2 more sources

Discovery of New Angucyclin(on)e Derivatives and Their Genetic Architecture from <i>Streptomyces</i> sp. SYP-A7185 in the Rhizosphere Soil of <i>Panax notoginseng</i>. [PDF]

ACS Omega
Xue JY, Wang CY, Wu YY, Zhang MY, Li S, Zhou XY, Zhang YX.   +6 more
europepmc   +1 more source

Improving Activity and Stability of Candida boidinii Formate Dehydrogenase Through Rational Active Site Engineering

ChemBioChem, Volume 27, Issue 15, 14 August 2026.
In search of improved biocatalysts for the NADH cofactor recycling in synthetic reductive biotransformations, C. boidinii formate dehydrogenase is the subject of a rational protein engineering approach. The study delivers an enzyme variant with improved specific activities and a more desirable pH and temperature profile, which shows promising ...
Marisa Bickmann, Andrea Rodil, Jan Deska
wiley   +1 more source

Comparative Characterization of Oxidative Enzymes for Arabinoxylan and Protein Cross-Linking via Ferulic Acid and Tyrosine in Model Systems. [PDF]

J Agric Food Chem
Hoefler K, Sukop U, Reiter E, Bender D, Jekle M, Roch P, Cichna-Markl M, D'Amico S, Schoenlechner R.   +8 more
europepmc   +1 more source

Extending Cofactor‐Tethered Nanomachines to Complex Multienzyme Redox Cascades in Continuous Flow

ChemSusChem, Volume 19, Issue 15, 14 August 2026.
Engineered enzyme fusions bearing covalently tethered PEG–nicotinamide cofactors enable intramolecular cofactor retention and recycling within self‐sufficient biocatalytic nanomachines. These nanomachines support cofactor‐autonomous operation of complex redox multienzyme cascades under continuous‐flow conditions, as demonstrated in a 10‐step glucose‐to‐
Zinnia Dsouza, Jan‐Simon Jeshua Friedrichs, Okke Melse, Gerhard Schenk, Volker Sieber   +4 more
wiley   +1 more source