Results 101 to 110 of about 1,090,848 (316)

Molecular insights into the VIRESCENS amino acid sequence and its implication in anthocyanin production in red- and yellow-fruited cultivars of date palm. [PDF]

Sci Rep, 2023
Alsuhaimi NM, Al-Kaff NS.
europepmc   +1 more source

Complete amino acid sequence of the N-terminal extension of calf skin type III procollagen [PDF]

, 1984
Anders Brandt, R W Glanville, D Hörlein, Peter Brückner, Rupert Timpl, Peter P. Fietzek, K. Kühn   +6 more
openalex   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Functional Roles of the Conserved Amino Acid Sequence Motif C, the Antiporter Motif, in Membrane Transporters of the Major Facilitator Superfamily. [PDF]

Biology (Basel), 2023
Varela MF, Ortiz-Alegria A, Lekshmi M, Stephen J, Kumar S.   +4 more
europepmc   +1 more source

Structural analysis of complementary DNA and amino acid sequences of human and rat androgen receptors.

, 1988
Cheng-Shyong Chang, John M. Kokontis, Shutsung Liao   +2 more
openalex   +2 more sources

Amino acid sequence of in vivo phosphorylation sites in the main intrinsic protein (MIP) of lens membranes [PDF]

, 1990
Paul D. Lampe, Ross G. Johnson
openalex   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Homology of amino acid sequences of rat liver cathepsins B and H with that of papain.

, 1983
Koji Takio, Takae Towatari, Nobuhiko Katunuma, D.C. Teller, Koiti Titani   +4 more
openalex   +2 more sources

N-Terminal amino acid sequence of pilin isolated from Pseudomonas aeruginosa [PDF]

, 1978
W Paranchych, Laura S. Frost, Michael R. Carpenter   +2 more
openalex   +1 more source