Results 21 to 30 of about 113,363 (75)
Predicting protein disorder by analyzing amino acid sequence
BMC Genomics, 2008 Background Many protein regions and some entire proteins have no definite tertiary structure, presenting instead as dynamic, disorder ensembles under different physiochemical circumstances.
Yang Mary, Yang Jack Y
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SSE: a nucleotide and amino acid sequence analysis platform
BMC Research Notes, 2012 Background There is an increasing need to develop bioinformatic tools to organise and analyse the rapidly growing amount of nucleotide and amino acid sequence data in organisms ranging from viruses to eukaryotes.
Simmonds Peter
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Amino acid classification based spectrum kernel fusion for protein subnuclear localization
BMC Bioinformatics, 2010 Background Prediction of protein localization in subnuclear organelles is more challenging than general protein subcelluar localization. There are only three computational models for protein subnuclear localization thus far, to the best of our knowledge.
Fei Wang, Mei Suyu
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Incorporating background frequency improves entropy-based residue conservation measures
BMC Bioinformatics, 2006 Background Several entropy-based methods have been developed for scoring sequence conservation in protein multiple sequence alignments. High scoring amino acid positions may correlate with structurally or functionally important residues.
Samudrala Ram, Wang Kai
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Distributed Representation of Protein Sequence Based on Multi-Alignment Results
Tehnički Vjesnik, 2020 Protein sequence representation is a key problem for protein studies, especially for those sequence-based models. In this paper, a distributed representation model of protein sequence is proposed, which involves evolutionary information by introducing ...
Siqi Wang, Liu He, Shi Cheng, Xiaohu Shi
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Spectral Analysis of Sequence Variability in Basic-Helix-loop-helix (bHLH) Protein Domains
Evolutionary Bioinformatics, 2006 The basic helix-loop-helix (bHLH) family of transcription factors is used as a paradigm to explore structural implications of periodicity patterns in amino acid sequence variability.
Zhi Wang, William R. Atchley
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Predicting DNA-binding sites of proteins from amino acid sequence
BMC Bioinformatics, 2006 Background Understanding the molecular details of protein-DNA interactions is critical for deciphering the mechanisms of gene regulation. We present a machine learning approach for the identification of amino acid residues involved in protein-DNA ...
Wu Feihong +5 more
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Amino acid sequence of rabbit apolipoprotein E.
Journal of Lipid Research, 1991 The complete amino acid sequence of rabbit apolipoprotein E (apoE) was determined by generating three sets of peptides using cyanogen bromide, endoproteinase AspN, and Staphylococcus aureus V8 protease to cleave the protein.
BR Lee +6 more
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Arquivos de GastroenterologiaBackground - Exposure to viral antigens that share amino acid sequence similar with self- antigens might trigger autoimmune diseases in genetically predisposed individuals, and the molecular mimicry theory suggests that epitope mimicry between the virus ...
Maristella de Araújo Carvalho SOUSA +2 more
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Protein sequence alignment with family-specific amino acid similarity matrices
BMC Research Notes, 2011 Background Alignment of amino acid sequences by means of dynamic programming is a cornerstone sequence comparison method. The quality of alignments produced by dynamic programming critically depends on the choice of the alignment scoring function ...
Kuznetsov Igor B
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