Growth-coupled selection of 5-aminolevulinic acid synthetase mutants for 5-aminolevulinic acid biosynthesis in Corynebacterium glutamicum [PDF]
Frontiers in MicrobiologyIntroduction5-Aminolevulinic acid (5-ALA) is a nonprotein amino acid with broad applications in agriculture, medicine, and the food industry. In recent years, substantial efforts have been devoted to enhancing its biosynthesis.
Peng Yang +11 more
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Sonodynamic Therapy Using 5-Aminolevulinic Acid for Malignant Gliomas: A Review [PDF]
LifeIn recent years, sonodynamic therapy (SDT) has attracted attention as a promising new approach for the treatment of high-grade gliomas, as it is a non-invasive form of therapy that specifically kills tumor cells with limited side effects.
Andrea Ebeling, Francesco Prada
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Photodynamic therapy using systemic administration of 5-aminolevulinic acid and a 410-nm wavelength light-emitting diode for methicillin-resistant Staphylococcus aureus-infected ulcers in mice. [PDF]
PLoS ONE, 2014 Bacterial resistance to antibiotics has become a worldwide problem. One potential alternative for bacterial control is photodynamic therapy. 5-aminolevulinic acid is a natural precursor of the photosensitizer protoporphyrin IX. Relatively little is known
Kuniyuki Morimoto +6 more
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Опухоли головы и шеи, 2022 Introduction. Treatment of the oral cavity is an important problem of current oncology due to high morbidity and mortality reaching 43 % in 5-year period after diagnosis.
Yu. V. Alymov +2 more
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Pharmaceuticals, 2023 Photodynamic therapy using delta-aminolevulinic acid is considered a promising option in the treatment of oral lichen planus. In the present work, three emulgel compositions prepared from natural polysaccharide gums, tragacanth, xanthan and gellan, were ...
Emilia Szymańska +7 more
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The use of 5-aminolevulinic acid and its derivatives in photodynamic therapy and diagnosis [PDF]
Biuletyn Wojskowej Akademii Technicznej, 2018 5-aminolevulinic acid (5-ALA) is used as a drug in the photodynamic therapy (PDT) and photodynamic diagnosis (PDD) of cancer. Combined with irradiation at the appropriate wavelength, it is used as a photosensitizer precursor to identify/kill tumour cells.
Anna Romiszewska, Aneta Bombalska
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5-Aminolevulinic Acid and Red Led in Endodontics: A Narrative Review and Case Report
Gels, 2022 The present study aims to discuss the main factors involving the use of 5-aminolevulinic acid together with red LED light and its application in endodontic treatment through a narrative review and a case report. Persistence of microorganisms remaining on
Simonetta D’Ercole +8 more
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5-Aminolevulinic acid improves chicken sperm motility [PDF]
Animal Bioscience, 2021 Objective This study investigated the effects of 5-aminolevulinic acid (5-ALA) on the motility parameters, mitochondrial membrane depolarization, and ATP levels in chicken sperm. Methods The pooled semen from Barred Plymouth Rock males was used.
Shin Taniguchi +4 more
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Effect of 5-aminolevulinic Acid on Mitochondrial Activity
Frontiers in Bioscience-Scholar, 2023 Background: Mitochondrial dysfunction is considered an important mechanism in the pathogenesis of various diseases. Therefore, mitochondria are currently being considered as subjects for targeted therapies, particularly, phototherapy using 5 ...
Yuliya V. Markina +6 more
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Case Report: Lack of Response to Givosiran in a Case of ALAD Porphyria
Frontiers in Genetics, 2022 Introduction: 5-Aminolevulinic acid dehydratase (ALAD) porphyria (ADP) is an autosomal recessive disease characterized by a profound deficiency in ALAD, the second enzyme in the heme biosynthetic pathway, and acute neurovisceral attacks with abdominal ...
Erica Graff +3 more
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