Fluorescence‐based discrimination of breast cancer cells by direct exposure to 5‐aminolevulinic acid
Cancer Medicine, 2019 Protoporphyrin IX‐fluorescence measurement is a powerful in situ approach for cancer detection after oral/topical administration of 5‐aminolevulinic acid.
Midori Morita +8 more
doaj +2 more sources
Growth-coupled selection of 5-aminolevulinic acid synthetase mutants for 5-aminolevulinic acid biosynthesis in Corynebacterium glutamicum [PDF]
Frontiers in MicrobiologyIntroduction5-Aminolevulinic acid (5-ALA) is a nonprotein amino acid with broad applications in agriculture, medicine, and the food industry. In recent years, substantial efforts have been devoted to enhancing its biosynthesis.
Peng Yang +11 more
doaj +2 more sources
Recurrence rate of perianal and intra-anal genital warts treated with aminolevulinic acid photodynamic therapy: a meta-analysis [PDF]
Frontiers in Reproductive HealthObjectiveThis meta-analysis and systematic review aimed to evaluate the recurrence rate and clinical efficacy of aminolevulinic acid photodynamic therapy (ALA-PDT) in the treatment of perianal and intra-anal genital warts.MethodsWe systematically ...
Mingqiang Liu +25 more
doaj +2 more sources
Plant Direct, 2018 δ‐aminolevulinic acid dehydratase (ALAD) is an important enzyme in tetrapyrrole synthesis. ALAD combines two δ‐aminolevulinic acid (δ‐ALA) molecules to form the pyrrole molecule, porphobilinogen, an important precursor for plant pigments involved in ...
Nabil Killiny +4 more
doaj +2 more sources
Sonodynamic Therapy Using 5-Aminolevulinic Acid for Malignant Gliomas: A Review [PDF]
LifeIn recent years, sonodynamic therapy (SDT) has attracted attention as a promising new approach for the treatment of high-grade gliomas, as it is a non-invasive form of therapy that specifically kills tumor cells with limited side effects.
Andrea Ebeling, Francesco Prada
doaj +2 more sources
Natural 5-Aminolevulinic Acid: Sources, Biosynthesis, Detection and Applications
Frontiers in Bioengineering and Biotechnology, 2022 5-Aminolevulinic acid (5-ALA) is the key precursor for the biosynthesis of tetrapyrrole compounds, with wide applications in medicine, agriculture and other burgeoning fields. Because of its potential applications and disadvantages of chemical synthesis,
Meiru Jiang +5 more
semanticscholar +1 more source
Advances in 5-Aminolevulinic Acid Priming to Enhance Plant Tolerance to Abiotic Stress
International Journal of Molecular Sciences, 2022 Priming is an adaptive strategy that improves plant defenses against biotic and abiotic stresses. Stimuli from chemicals, abiotic cues, and pathogens can trigger the establishment of priming state.
Shuya Tan, Jie Cao, X. Xia, Zhonghai Li
semanticscholar +1 more source
Turning on the light for brain tumor surgery: A 5-aminolevulinic acid story
Neuro-Oncology, 2022 To aid surgeons in more complete and safe resection of brain tumors, adjuvant technologies have been developed to improve visualization of target tissue.
D. McCracken +5 more
semanticscholar +1 more source
Photodynamic therapy using systemic administration of 5-aminolevulinic acid and a 410-nm wavelength light-emitting diode for methicillin-resistant Staphylococcus aureus-infected ulcers in mice. [PDF]
PLoS ONE, 2014 Bacterial resistance to antibiotics has become a worldwide problem. One potential alternative for bacterial control is photodynamic therapy. 5-aminolevulinic acid is a natural precursor of the photosensitizer protoporphyrin IX. Relatively little is known
Kuniyuki Morimoto +6 more
doaj +1 more source
Pharmaceuticals, 2023 Photodynamic therapy using delta-aminolevulinic acid is considered a promising option in the treatment of oral lichen planus. In the present work, three emulgel compositions prepared from natural polysaccharide gums, tragacanth, xanthan and gellan, were ...
Emilia Szymańska +7 more
doaj +1 more source