Results 91 to 100 of about 9,790 (260)

Presence of Nitrites, Nitrates, Nitrosamines in the Eggs of Intensively raised Layers in Abeokuta, Nigeria [PDF]

, 2016
In this study, the presence and concentrations of nitrosamines and their precursors (nitrates and nitrites) in raw table eggs obtained from four layer-farms in Abeokuta, were analysed.
Aduloju, O. S., Ajibola, E. S., Maduagwu, E. N., Okediran, B., Thomas, F. C.   +4 more
core   +2 more sources

Equine botulism

Equine Veterinary Journal, EarlyView.
Abstract Botulism is a severe and often fatal disease in equine patients worldwide. Clostridium botulinum is a ubiquitous soil organism which produces a potent neurotoxin resulting in neuromuscular blockade and flaccid paralysis in affected animals. Definitive diagnosis is often impractical or impossible, leading to diagnosis and treatment based on ...
Kali Slavik, Robert Whitlock, Amy Johnson   +2 more
wiley   +1 more source

Structural diversity of different aminomethylpyridinium hexafluoridosilicates

Acta Chimica Slovenica
A series of new aminomethylpyridinium hexafluoridosilicate salts with the formula (RH)2[SiF6] (where R = 2-amino-3-methylpyridine (1), 2-amino-4-methylpyridine (2), 2-amino-5-methylpyridine (3) and 2-amino-6-methylpyridine (4)) were prepared by the ...
Andrej Pevec
doaj   +1 more source

Blebbistatin reduces calcium buffering in cardiomyocytes: Consequences for cellular electrophysiology

The Journal of Physiology, EarlyView.
Abstract figure legend Blebbistatin reduces Ca2+ buffering in induced pluripotent stem cell‐derived atrial cardiomyocytes. Blebbistatin, a widely used excitation–contraction uncoupling agent, decreases calcium (Ca2+) buffer affinity (increased buffer dissociation constant), leading to elevated diastolic Ca2+ levels, increased sarcoplasmic reticulum Ca2+
Izzatullo Sobitov, Katharina Ritzenhoff, Marie Gaulrapp, Lea Becker, Aiste Liutkute, Fitzwilliam Seibertz, Funsho E. Fakuade, Fleur E. Mason, Niels Voigt   +8 more
wiley   +1 more source

Deciphering pro‐arrhythmogenic mechanisms of EPAC in human atrial cardiomyocytes

The Journal of Physiology, EarlyView.
Abstract figure legend This study aimed to investigate the effect of exchange proteins directly activated by cAMP (EPAC) on the regulation of human atrial cardiomyocyte electrophysiology and their potential involvement in the onset of atrial fibrillation (AF).
Arthur Boileve, Margaux Aize, Maximin Détrait, Laura Brard, Adrien Leboyer, Pierre‐Antoine Dupont, Alexandre Lebrun, Vladimir Saplacan, Christophe Simard, Fabien Brette, Frank Lezoualc'h, Laurent Sallé   +11 more
wiley   +1 more source

Characteristics of weak base-induced vacuoles formed around individual acidic organelles

Folia Histochemica et Cytobiologica, 2011
We have previously found that the weak base 4-aminopyridine induces Brownian motion of acidic organelles around which vacuoles are formed, causing organelle traffic disorder in neurons.
Tadashi Kawakami, Hiromi Hiruma
doaj   +1 more source

Palladium-Catalyzed Amination of Unprotected Five-Membered Heterocyclic Bromides [PDF]

, 2013
An efficient method for the palladium-catalyzed amination of unprotected bromoimidazoles and bromopyrazoles is presented. The transformation is facilitated by the use of our newly developed Pd precatalyst based on the bulky biarylphosphine ligand ...
Buchwald, Stephen Leffler, Hoshiya, Naoyuki, Su, Mingjuan   +2 more
core   +1 more source

Inhibitory GABAergic Neuron Loss due to Oxidative Damage During Ex Vivo Acute Brain Slice Preparation Influences Genesis and Dynamics of Epileptiform Activity

Journal of Neurochemistry, Volume 170, Issue 2, February 2026.
Ex vivo brain slice preparation is a popular technique in neuroscience research with many variations in preparation method. We compared two popular variations in brain slice preparation and found that the choice of brain slice preparation technique significantly affects the viability of neuronal preparation.
Felix Chan, Anupam Hazra, Ashan Jayasekera, Katherine Huang, Shuna Whyte, Leolie Telford‐Cooke, Kamilah Lakhani, Xiaomeng Li, Rebecca Shields, Angeline Kosim, Darwin Su, Carol Murray, Mark O. Cunningham   +12 more
wiley   +1 more source

Heterocycle-based bifunctional organocatalysts in asymmetric synthesis [PDF]

, 2016
Different chiral bifunctional organocatalysts derived from trans-cyclohexane-1,2-diamine bearing different types of guanidine units able to form-hydrogen bonding activation have been designed. Conformational rigid 2-aminobenzimidazoles bearing a tertiary
Gómez Bengoa, Enrique, Nájera, Carmen, Sansano, Jose M.   +2 more
core   +2 more sources

Generalization of seizures parallels the formation of "dark" neurons in the hippocampus and pontine reticular formation after focal-cortical application of 4-aminopyridine (4-AP) in the rat. [PDF]

, 2008
Distribution and time course of the occurrence of "dark" neurons were compared with the EEG activity and behavior of rats during 4-aminopyridine (4-AP) induced epileptic seizures. A crystal of the K(+) channel blocker 4-AP (0.5 mg/kg) was placed onto the
Baracskay, P, Czurkó, A., Juhász, G, ORBAN, Gergely, Szepesi, Z   +4 more
core   +1 more source