Results 31 to 40 of about 9,790 (260)
Synthesis of carbon-11-labeled isonicotinamides as new potential PET agents for imaging of GSK-3 enzyme in Alzheimer’s disease [PDF]
, 2017 The authentic standards 2-(cyclopropanecarboxamido)-N-(4-methoxypyridin-3-yl)isonicotinamide (4a) and 2-(cyclopropanecarboxamido)-N-(4-(4-methoxyphenyl)pyridin-3-yl)isonicotinamide (7a), and their corresponding precursors 2-(cyclopropanecarboxamido)-N-(4-
Gao, Mingzhang +2 more
core +2 more sources
Molecules, 2023 A facile, green, synthetic protocol of several substituted N-(pyridin-2-yl)imidates from nitrostyrenes and 2-aminopyridines via the corresponding N-(pyridin-2-yl)iminonitriles as intermediates is reported.
Andriani G. Chaidali, Ioannis N. Lykakis
doaj +1 more source
A structural systematic study of three isomers of difluoro-N-(4-pyridyl)benzamide [PDF]
, 2008 The isomers 2,3-, (I), 2,4-, (II), and 2,5-difluoro-N-(4-pyridyl)benzamide, (III), all with formula C₁₂H₈F₂N₂O, all exhibit intramolecular C-H...O=C and N-H...F contacts [both with S(6) motifs].
Anderson, Frankie P. +3 more
core +1 more source
Angewandte Chemie, EarlyView.This work reports, for the first time, aggregation‐ or crystallization‐induced emission in boron‐substituted carboranes, which was driven by photoinduced charge‐transfer from fluorophore attached via boron vertices. The emission properties can be tuned by varying the substituents, expanding design strategies for luminescent materials.
Balázs Szathmári +9 more
wiley +2 more sources
Scientific Reports, 2017 Botulinum neurotoxins (BoNTs) are highly potent toxins that cleave neuronal SNARE proteins required for neurotransmission, causing flaccid paralysis and death by asphyxiation.
Phillip H. Beske +4 more
doaj +1 more source
Beilstein Journal of Organic Chemistry, 2022 Novel pyridine-based fluorescing compounds, viz. pyrido[1,2-a]pyrrolo[3,4-d]pyrimidines 3a,b and N-methyl-4-((pyridin-2-yl)amino)maleimides 4a–e, were selectively prepared by a one-pot reaction between a functionalized maleimide and 2-aminopyridines with
Masayori Hagimori +4 more
doaj +1 more source
4-Aminopyridine — A Review [PDF]
Anaesthesia and Intensive Care, 1982 4-aminopyridine is the first of the aminopyridines to be used in clinical practice. It blocks potassium channels and thereby increases acetylcholine, and possibly noradrenaline, release at nerve terminals. In man the drug has a significant action at the neuromuscular junction, but has little effect on the autonomic nervous system or muscle (smooth ...
N, Soni, P, Kam
openaire +2 more sources
Pyridinium N-2 '-pyridylaminide: radical cyclization in the synthesis of annulated 2-aminopyridines [PDF]
, 2006 The synthesis of annulated 2-aminopyridines by intramolecular radical pyridylation of the appropriate substrates, obtained from pyridinium N-2'-pyridylaminide, can be performed using TTMSS and AIBN.Financial support by the CICYT (Project CTQ2005-08902 ...
Burgos García, Carolina +3 more
core +3 more sources
Plasmonic Hot‐Carrier Redox Enables Proton‐Coupled Electron Transfer at C─H Bonds
Angewandte Chemie, EarlyView.Plasmonic hot carriers provide unprecedented control over coupled electron–proton transfer, enabling visible‐light activation of strong C─H bonds. Using an energy‐filter electrode, we reveal a stepwise electron‐then‐proton pathway and directly tune the underlying driving forces.
Daniel Velev Latchev +3 more
wiley +2 more sources
One-pot synthesis of tetracyclic fused imidazo[1,2-a]pyridines via a three-component reaction
Beilstein Journal of Organic Chemistry, 2016 A novel three-component reaction has been developed to assemble biologically and pharmaceutically important tetracyclic fused imidazo[1,2-a]pyridines in a one-pot fashion utilizing readily available 2-aminopyridines, isatins and isocyanides.
Bo Yang +4 more
doaj +1 more source