Results 41 to 50 of about 9,790 (260)
Improvement of diaphragm and limb muscle isotonic contractile performance by K+ channel blockade
Journal of NeuroEngineering and Rehabilitation, 2010 The K+ channel blocking aminopyridines greatly improve skeletal muscle isometric contractile performance during low to intermediate stimulation frequencies, making them potentially useful as inotropic agents for functional neuromuscular stimulation ...
Pollarine Jennifer, van Lunteren Erik
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A structural systematic study of four isomers of difluoro-N-(3-pyridyl)benzamide [PDF]
, 2009 The four isomers 2,4-, (I), 2,5-, (II), 3,4-, (III), and 3,5-difluoro-N-(3-pyridyl)benzamide, (IV), all with formula C12H8F2N2O, display molecular similarity, with interplanar angles between the C6/C5N rings ranging from 2.94 (11)° in (IV) to 4.48 (18 ...
Anderson, Frankie P. +3 more
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4-Aminopyridine Improves Lower Urinary Tract Symptoms in a Patient With Benign Prostatic Hyperplasia and Downbeat Nystagmus Syndrome [PDF]
International Neurourology Journal, 2014 Aminopyridines are potassium channel blockers that increase the excitability of nerve cells and axons; therefore, they are widely used to treat different neurological disorders.
Michael Strupp +3 more
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Molbank, 2021 Synthesis of a series of the substituted [(pyridinyl and pyrimidin-2-ylimino)-ethyl]-4-hydroxy-chromen-2-ones and their tetrazole derivates is presented in this study. By catalytic condensation of 4-hydroxy-3-acetylcoumarine 2 and 2-aminopyridines 3(a-d),
Ramiz Hoti +5 more
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Tackling resistance: Emerging antimalarials and new parasite targets in the era of elimination [version 1; referees: 2 approved] [PDF]
, 2018 Malaria remains a significant contributor to global human mortality, and roughly half the world’s population is at risk for infection with Plasmodium spp. parasites.
Matthews, Emily S, Odom John, Audrey R
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Molecules, 2007 An improved synthetic method affording 4-chlorocoumarin-3-sulfonyl chloride (4) in very good yield (ca. 85 %) is reported. This compound was reacted with various bidentate nucleophiles such as 2-aminopyridines and 2-aminothiazoles in order to obtain ...
Emil Popovski +4 more
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Molecules, 2022 A new and suitable multicomponent one-pot reaction was developed for the synthesis of 2-amino-3-cyanopyridine derivatives. Background: This synthesis was demonstrated by the efficient and easy access to a variety of substituted 2-aminopyridines using ...
Zahira Kibou +6 more
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Template-directed synthesis of macrocyclic aminopyridines: azacalix[n](2,6)pyridines (n = 3, 4) [PDF]
, 2014 Template-induced synthetic routes for azacalix[n](2,6)pyridines (n = 3, 4) have been elaborated. The proton and nickel ion served as the efficient template for the cyclization reactions, and the presence of the templates preferentially afforded the ...
Kuwabara Junpei +5 more
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Preparation of imidazo[1,2-a]-N-heterocyclic derivatives with gem-difluorinated side chains
Beilstein Journal of Organic Chemistry, 2017 Using an aerobic oxidative coupling, different new imidazo[1,2-a]-N-heterocycles with gem-difluroroalkyl side chains have been prepared in fair yields by the reaction of gem-difluoroenones with aminopyridines, -pyrimidines and -pyridazines.
Layal Hariss +5 more
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METHODS OF NITROPYRIDINE SYNTHESIS
Siberian Journal of Life Sciences and Agriculture, 2021 Background. Pyridine derivatives are widely used in pharmaceuticals, agrochemistry, as well as in the production of new materials. The pyridine and piperidine rings are the main structural fragments of numerous natural alkaloids with a wide spectrum of ...
Evgeniya V. Ivanova +4 more
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