Results 11 to 20 of about 6,120 (213)
Excited-state relaxation of some aminoquinolines [PDF]
International Journal of Photoenergy, 2006 The absorption and fluorescence spectra, fluorescence quantum yields and lifetimes, and fluorescence rate constants ( k f ) of 2-amino-3-( 2 ′ -benzoxazolyl)quinoline (I), 2-amino-3-( 2 ′ ...
M. N. Khimich, B. M. Uzhinov
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Antimalarials with Benzothiophene Moieties as Aminoquinoline Partners [PDF]
Molecules, 2017 Malaria is a severe and life-threatening disease caused by Plasmodium parasites that are spread to humans through bites of infected Anopheles mosquitoes.
Jelena Konstantinović +6 more
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Regiodivergent C3 and C4 Amination of Quinolines via Radical and Ionic Pathways. [PDF]
Angew Chem Int Ed EnglA regiodivergent strategy converts a single N‐aminoquinolinium precursor into either C3‐ or C4‐aminated quinolines. Nucleophile‐induced dearomatization diverges into light‐driven N‐centered radical capture (C3) or base‐promoted SNAr (C4), enabling rapid assembly of aminoquinoline libraries and late‐stage diversification.
Kim YE, Kim J, Lee J, Hong S.
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The Trypanosoma cruzi enzyme TcGPXI is a glycosomal peroxidase and can be linked to trypanothione reduction by glutathione or tryparedoxin. [PDF]
, 2002 Trypanosoma cruzi glutathione-dependent peroxidase I (TcGPXI) can reduce fatty acid, phospholipid, and short chain organic hydroperoxides utilizing a novel redox cycle in which enzyme activity is linked to the reduction of trypanothione, a parasite ...
Docampo +56 more
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Heliyon, 2020 Quantitative structure–activity relationships (QSAR) provides a model that link biological activities of compounds to thier chemical stuctures and molecular docking study reveals the interaction between drug and its target enzyme.
Aliyu Wappah Mahmud +2 more
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Anti‐malarial drug effects on parasite dynamics in vivax malaria
Malaria Journal, 2021 Relapses of Plasmodium vivax malaria are prevented by 8-aminoquinolines. If hypnozoites survive, then the subsequent blood stage infections in early relapses (
Nicholas J. White
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Ribofuranose as a carrier of tetraoxane and 4-aminoquinoline antimalarial pharmacophores [PDF]
Journal of the Serbian Chemical Society, 2008 Several tetraoxane and 4-aminoquinoline molecules were prepared in order to examine the influence of ribofuranose as a carrier molecule on the antimalarial activity of test compounds.
IGOR M. OPSENICA +4 more
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Aminoquinoline Derivatives as HCV Inhibitors [PDF]
ACS Medicinal Chemistry Letters, 2013 Aminoquinoline Derivatives as HCV Inhibitors Jean-Francois Brazeau and Gerard Rosse* Structure Guided Chemistry, Dart Neuroscience LLC, 7473 Lusk Boulevard, San Diego, California 92121, United States Adjunct Associate Professor, Department of Pharmacology and Physiology, College of Medicine, Drexel University, New College Building, 245 North 15th ...
Jean-Francois, Brazeau, Gerard, Rosse
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Biomolecules, 2023 The 4-aminoquinoline drugs, such as chloroquine (CQ), amodiaquine or piperaquine, are still commonly used for malaria treatment, either alone (CQ) or in combination with artemisinin derivatives.
Nicoletta Basilico +14 more
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Repurposing antimalarial aminoquinolines and related compounds for treatment of retinal neovascularization. [PDF]
PLoS ONE, 2018 Neovascularization is the pathological driver of blinding eye diseases such as retinopathy of prematurity, proliferative diabetic retinopathy, and wet age-related macular degeneration.
Danielle McAnally +19 more
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