Results 71 to 80 of about 6,032 (181)

Synthesis and biological evaluation of some 4-aminoquinoline derivatives as potential antitubercular agents

Future Journal of Pharmaceutical Sciences, 2020
Background Based on bioisosteric similarities with thiacetazone, a series of 7-chloro-4-aminoquinoline derivatives have been designed and synthesized. The target compounds were elucidated by NMR, mass, and FTIR spectral data.
Shankar Alegaon, Kamlesh Kashniyal, Sanket Kuncolienkar, Rohini Kavalapure, Preeti Salve, Mahesh Palled, Shailendra Suryawanshi, Sunil Jalalpure   +7 more
doaj   +1 more source

Molecular evidence of incipient speciation within Anopheles gambiae s.s. in West Africa [PDF]

, 2001
We karyotyped and identified by polymerase chain reaction restriction fragment length polymorphism (PCR-RFLP) analysis Anopheles gambiae s.s. samples collected in several African countries. The data show the existence of two non-panmictic molecular forms,
Akogbeto, M, Coluzzi, M, della Torre, A, Dossou-Yovo, J, Fanello, C, Favia, G, Petrarca, V   +6 more
core   +1 more source

Resistant Plasmodium Falciparum Infection From Samarinda, Kalimantan [PDF]

, 1974
Rumah Sakit Caltex di Rumbai, Pekanbaru pernah melaporkan adanya P. falciparum yang resistent terhadap chloroquine. Setelah dilakukan follow up ternyata kasus ini masih sangat sensitive terhadap group 4 aminoquinoline.
Arwati, A. (Arwati), Verdrager, J. (J)
core  

Synthesis of 4-Aminoquinolines

, 1965
4-Anilinoquinolines have been prepared by cyclodehydration of \(\beta\)-anilinoacryloanilides with polyphosphoric acid.
A. K. Sen, (Miss) Kalyani Mitra
openaire   +1 more source

Artemether resistance in vitro is linked to mutations in PfATP6 that also interact with mutations in PfMDR1 in travellers returning with Plasmodium falciparum infections. [PDF]

, 2012
BACKGROUND: Monitoring resistance phenotypes for Plasmodium falciparum, using in vitro growth assays, and relating findings to parasite genotype has proved particularly challenging for the study of resistance to artemisinins.
Khairnar, K, Krishna, S, Lau, R, Lepore, R, Pillai, DR, Staines, HM, Via, A   +6 more
core   +1 more source

Blocking Plasmodium falciparum Malaria Transmission with Drugs: The Gametocytocidal and Sporontocidal Properties of Current and Prospective Antimalarials

Pharmaceuticals, 2010
Drugs that kill or inhibit the sexual stages of Plasmodium could potentially amplify or synergize the impact of other interventions by blocking transmission to mosquitoes.
Anthony E. Kiszewski
doaj   +1 more source

The use of ultrasensitive quantitative-PCR to assess the impact of primaquine on asymptomatic relapse of Plasmodium vivax infections: a randomized, controlled trial in Lao PDR

Malaria Journal, 2020
Background Trials to assess the efficacy of the radical cure of Plasmodium vivax malaria with 8-aminoquinolines require that most post-treatment relapses are identified, but there is no consensus on the optimal duration of follow-up in either symptomatic
Koukeo Phommasone, Frank van Leth, Mallika Imwong, Gisela Henriques, Tiengkham Pongvongsa, Bipin Adhikari, Thomas J. Peto, Cholrawee Promnarate, Mehul Dhorda, Pasathorn Sirithiranont, Mavuto Mukaka, Pimnara Peerawaranun, Nicholas P. J. Day, Frank Cobelens, Arjen M. Dondorp, Paul N. Newton, Nicholas J. White, Lorenz von Seidlein, Mayfong Mayxay   +18 more
doaj   +1 more source

Clinical Laboratory Parameters Among Adult Males During a Primaquine Chemoprophylaxis Trial in Irian Jaya, Indonesia [PDF]

, 1995
Primakuin yang digunakan sebagai profilaksis malaria terbukti efektif dan diterima dengan baik oleh tubuh manusia yang normal terhadap aktivitas enzim 6 glukosa-6 fosfat dehidrogenase (G-6PD).
Baird, J. K. (J), Fryauff, D. J. (David), Hadiputranto, H. (Hilda), Hoffman, S. L. (Stephen), Larasati, R. P. (Ria), Mouzin, E. (Eric), Pudjoprawoto, N. (Nurani), Ratiwayanto, S. (Sutanti), Richards, A. L. (Allen), Richie, T. L. (Thomas), Sandjaya, B. (Bartolomeus), Subianto, B. (Budi), Sutamihardja, M. A. (Mochammad), Tjitra, E. (Emiliana), Wignall, F. S. (F)   +14 more
core  

SYNTHESIS OF 8-AMINOQUINOLINES. PART VII

, 1957
Synthesis of 7-chioro-2-methyl-8-amino-4-(4’-hydroxy-3'-diethylaminomethyl)-anilinoquinaldine has been described.
ACHINTYA K. SEN, U. P. BASU
openaire   +1 more source

CPP-ZFN: A potential DNA-targeting anti-malarial drug [PDF]

, 2010
Background Multidrug-resistant Plasmodium is of major concern today. Effective vaccines or successful applications of RNAi-based strategies for the treatment of malaria are currently unavailable.
Vikrant Nain, Shakti Sahi, Anju Verma
core   +2 more sources