Results 71 to 80 of about 6,120 (213)

THE ACTIVITY OF 4-AMINOQUINOLINE AGAINST PLASMODIUM FALCIPARUM IN SOUTHERN IRAN

open access: yesIranian Journal of Public Health, 1973
The resistance of Plasmodium falciparum to 4-amioquinolines has been confirmed in parts of South America such as Venezuela, Colombia, Brazil and Panama since 1961. During 1968-1970, 147 P.
AV. Manouchehri   +2 more
doaj  

Polycationic Peptides That Bind T‐Box Riboswitch Antiterminator RNA and Inhibit Riboswitch Function

open access: yesChemical Biology &Drug Design, Volume 107, Issue 5, May 2026.
Polycationic decapeptides inhibit T‐box riboswitch tRNA‐induced transcription readthrough. ABSTRACT Resistance to antibiotic treatments continues to be a significant health challenge and necessitates investigating novel antibacterial targets including noncoding regulatory RNA.
Emily Fairchild   +8 more
wiley   +1 more source

Epidemiological distribution of Plasmodium falciparum drug resistance in Brazil and its relevance to the treatment and control of malaria

open access: yesMemorias do Instituto Oswaldo Cruz, 1992
With the use of a simple formulary, field by health agents was ewstablished a monitoring programme for responses of P. falciparum to the antimalarial drugs.
José Maria de Souza
doaj   +1 more source

Review of pyronaridine anti-malarial properties and product characteristics. [PDF]

open access: yes, 2012
Pyronaridine was synthesized in 1970 at the Institute of Chinese Parasitic Disease and has been used in China for over 30 years for the treatment of malaria.
Arbe-Barnes, Sarah J   +7 more
core   +2 more sources

Tomato Spotted Wilt Virus Reprogrammes Host Glycolysis to Facilitate Proliferation by a Phase‐Separated Co‐Aggregate of Nucleocapsid Protein and Phosphoglycerate Kinase

open access: yesPlant Biotechnology Journal, Volume 24, Issue 5, Page 2826-2842, May 2026.
ABSTRACT Efficient viral proliferation within the host is a critical step in pathogenicity and requires adenosine triphosphate (ATP). The replication, movement and immune evasion of many plant viruses within their hosts are associated with phase separation (PS)‐derived aggregates formed by viral components.
Guangcheng Zu   +8 more
wiley   +1 more source

Molecular Markers of In Vivo Plasmodium vivax Resistance to Amodiaquine Plus Sulfadoxine-Pyrimethamine: Mutations in pvdhfr and pvmdr1 [PDF]

open access: yes, 2017
Background. Molecular markers for sulfadoxine-pyrimethamine (SP) resistance in Plasmodium vivax have been reported. However, data on the molecular correlates involved in the development of resistance to 4-aminoquinolines and their association with the in
Barbollat, Laetitia   +10 more
core  

Modulation of Antimalarial Activity at a Putative Bisquinoline Receptor in vivo Using Fluorinated Bisquinolines [PDF]

open access: yes
Antimalarials can interact with heme covalently, by - interactions or hydrogen bonding. Consequently, the prototropy of 4-aminoquinolines and quinoline methanols was investigated using quantum mechanics.
Alizadeh, S   +14 more
core   +1 more source

Antimalarial and antimicrobial activities of 8-aminoquinoline-uracils metal complexes [PDF]

open access: yes, 2016
8-Aminoquinoline (8AQ) derivatives have been reported to have antimalarial, anticancer, and antioxidant activities. This study investigated the potency of 8AQ-5-substituted (iodo and nitro) uracils metal (Mn, Cu, Ni) complexes (1-6) as antimalarial and ...
Kunwittaya, Sarun   +6 more
core   +1 more source

Synthesis of 4-Aminoquinolines

open access: yes, 1965
4-Anilinoquinolines have been prepared by cyclodehydration of \(\beta\)-anilinoacryloanilides with polyphosphoric acid.
A. K. Sen, (Miss) Kalyani Mitra
openaire   +2 more sources

Recent developments in 8-aminoquinoline antimalarials [PDF]

open access: yes, 1984
Malaria is an old scourge of mankind and mention of the disease is found in ancient writings in India, Egypt and China [1]. The clinical symptoms of this disease were described by Hippocrates 400 years before the Christian era [1]. Human population affected by malaria is alarmingly large in tropical regions although in the past the disease was also ...
B K, Bhat, M, Seth, A P, Bhaduri
openaire   +2 more sources

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