Results 21 to 30 of about 66,736 (230)

Copine-6 is a Ca2+ sensor for activity-induced AMPA receptor exocytosis

Cell Reports, 2023
Summary: The recruitment of synaptic α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) receptors underlies the strengthening of neuronal connectivity during learning and memory. This process is triggered by N-methyl-D-aspartate (NMDA) receptor-
Jing Zhi Anson Tan, Se Eun Jang, Ana Batallas-Borja, Nishita Bhembre, Mintu Chandra, Lingrui Zhang, Huimin Guo, Mitchell T. Ringuet, Jocelyn Widagdo, Brett M. Collins, Victor Anggono   +10 more
doaj   +1 more source

Progesterone monitoring and gestation length in Amazonian manatees (Trichechus inunguis)

Theriogenology Wild
Knowledge of pregnancy length and the physiological parameters during pregnancy is an important tool for pregnancy diagnosis in free-ranging and captive individuals and for the correct husbandry of captive pregnant females. Therefore, this study aimed to
Rodrigo S. Amaral, Vera M.F. da Silva, José Anselmo d’Affonsêca Neto   +2 more
doaj   +1 more source

AMPA-ergic regulation of amyloid-β levels in an Alzheimer’s disease mouse model

Molecular Neurodegeneration, 2018
Background Extracellular aggregation of the amyloid-β (Aβ) peptide into toxic multimers is a key event in Alzheimer’s disease (AD) pathogenesis. Aβ aggregation is concentration-dependent, with higher concentrations of Aβ much more likely to form toxic ...
Jane C. Hettinger, Hyo Lee, Guojun Bu, David M. Holtzman, John R. Cirrito   +4 more
doaj   +1 more source

CSF Levels of NPTX2 Are Associated With Less Brain Atrophy Over Time in Cognitively Unimpaired Individuals

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Neuronal pentraxin 2 (NPTX2) is a synaptic protein involved in synaptic plasticity and regulation of neuronal excitability. Lower baseline cerebrospinal fluid (CSF) NPTX2 levels have been shown to be associated with an earlier onset of mild cognitive impairment (MCI), a pre‐dementia syndrome, even after CSF Alzheimer's Disease (AD)
Juan P. Vazquez, Corinne Pettigrew, Yuxin Zhu, Claire Anderson, Guray Erus, Christos Davatzikos, Michael Miller, Abhay Moghekar, Sungtaek Oh, Chan‐Hyun Na, Marilyn Albert, Paul Worley, Anja Soldan   +12 more
wiley   +1 more source

Structure Elucidation and Immunoactivity Study of Armillaria mellea Fruiting Body Polysaccharides

Separations, 2023
Polysaccharides are the main nutritional constituents in the Armillaria mellea fruiting bodies. The structure and immunoactivity of Armillaria mellea polysaccharide are valuable to be determined for development. In the present study, two polysaccharides,
Qingqing Li, Ying Li, Huazhou Niu, Enhui Wang, Lili Jiao, Hui Li, Wei Wu   +6 more
doaj   +1 more source

Clinical Characteristics and Outcomes of Early‐Onset Versus Late‐Onset LGI1‐Antibody Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Leucine‐rich glioma‐inactivated 1 antibody (LGI1‐Ab) encephalitis predominantly affected older individuals, but has also been reported in younger patients. However, the demographic, clinical, and prognostic characteristics of early‐onset LGI1‐Ab encephalitis have yet to be systematically elucidated. This study aims to systematically
Yu Kong, Shasha Yu, Jing Zhang, Yu Zu, Yujing Zhang, Jing Lv, Xuyang Cao, Xuedan Feng   +7 more
wiley   +1 more source

A Study on Attitude of Pre-service Secondary Teachers Towards Human Rights Education and Peace Education

Dera Natung Government College Research Journal, 2016
The investigators conducted a study to know the attitude towards Human Rights Edu- cation and Peace Education of pre-service secondary teachers of Department of Education, Rajiv Gandhi University, Hills College of Teacher Education and Donyi-Polo B.Ed ...
Sony Dupak, Tage Ampa
doaj   +1 more source

Insights Into the Antigenic Repertoire of Unclassified Synaptic Antibodies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We sought to characterize the sixth most common finding in our neuroimmunological laboratory practice (tissue assay‐observed unclassified neural antibodies [UNAs]), combining protein microarray and phage immunoprecipitation sequencing (PhIP‐Seq). Methods Patient specimens (258; 133 serums; 125 CSF) meeting UNA criteria were profiled;
Michael Gilligan, John R. Mills, Paulina Vargas, Naveen K. Paramasivan, Connie E. Lesnick, Eati Basal, Surendra Dasari, James P. Fryer, Shannon R. Hinson, Joseph Laporta, Amy Espinal, Dennis Fitzgerald, Carolina Garcia, Anna E. Morenkova, Paola Pergami, Anna Shah, Andrew Knight, Reghann LaFrance Corey, Vanda A. Lennon, Anastasia Zekeridou, Sean J. Pittock, Divyanshu Dubey, Andrew McKeon   +22 more
wiley   +1 more source

Potencial de Chlorophytum comosum para la remediación de suelos contaminados con glifosato

Terra Latinoamericana
El glifosato es un herbicida ampliamente utilizado, pero su uso excesivo ha generado preocupaciones por sus posibles efectos negativos en la salud humana y al ambiente debido a su persistencia en el suelo. La fitorremediación es el uso de la capacidad de
Pedro Sandoval-Estrada, Ana Belem Piña-Guzmán , Dioselina Álvarez-Bernal, Marina Olivia Franco-Hernández, Fabián Robles-Martínez   +4 more
doaj   +1 more source

Determination of hydrophilic–lipophilic balance value and emulsion properties of sacha inchi oil

Asian Pacific Journal of Tropical Biomedicine, 2017
Objective: To determine hydrophilic–lipophilic balance (HLB) value, stability of formulate emulsion and properties of sacha inchi oil. Methods: The physiochemical characteristics of sacha inchi oil were first investigated.
Kiattiphumi Saengsorn, Ampa Jimtaisong
doaj   +1 more source