Results 31 to 40 of about 150,350 (378)
A sex difference in the response of the rodent postsynaptic density to synGAP haploinsufficiency [PDF]
, 2020 SynGAP is a postsynaptic density (PSD) protein that binds to PDZ domains of the scaffold protein PSD-95. We previously reported that heterozygous deletion of Syngap1 in mice is correlated with increased steady-state levels of other key PSD proteins that ...
Basu, Shinjini +6 more
core +3 more sources
Glyphosate, but not its metabolite AMPA, alters the honeybee gut microbiota
PLoS ONE, 2019 The honeybee (Apis mellifera) has to cope with multiple environmental stressors, especially pesticides. Among those, the herbicide glyphosate and its main metabolite, the aminomethylphosphonic acid (AMPA), are among the most abundant and ubiquitous ...
Nicolas Blot +3 more
semanticscholar +1 more source
Cells, 2022 The ionotropic glutamate receptor subtype α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) is responsible for most excitatory transmission in the brain.
Mohammad Qneibi +3 more
doaj +1 more source
Chemokine fractalkine/CX3CL1 negatively modulates active glutamatergic synapses in rat hippocampal neurons [PDF]
, 2006 We examined the effects of the chemokine fractalkine (CX3CL1) on EPSCs evoked by electrical stimulation of Schaffer collaterals in patch-clamped CA1 pyramidal neurons from rat hippocampal slices.
BERTOLLINI, Cristina +8 more
core +1 more source
LGI1 antibodies alter Kv1.1 and AMPA receptors changing synaptic excitability, plasticity and memory
Brain : a journal of neurology, 2018 Leucine-rich glioma-inactivated 1 (LGI1) is a secreted neuronal protein that forms a trans-synaptic complex that includes the presynaptic disintegrin and metalloproteinase domain-containing protein 23 (ADAM23), which interacts with voltage-gated ...
Mar Petit-Pedrol +12 more
semanticscholar +1 more source
AMPA receptor trafficking and learning [PDF]
European Journal of Neuroscience, 2010 AbstractIn the last few years it has become clear that AMPA‐type glutamate neurotransmitter receptors are rapidly transported into and out of synapses to strengthen or weaken their function. The remarkable dynamics of AMPA receptor (AMPAR) synaptic localization provides a compelling mechanism for understanding the cellular basis of learning and memory,
Zhaoqing Zheng, Joyce Keifer
openaire +3 more sources
Revisión sobre la relación del genotipo para APOE4 y el desarollo de demencia tipo Alzheimer
Revista Clínica de la Escuela de Medicina UCR-HSJD, 2011 Introducción: La enfermedad de tipo Alzheimer es la causa más frecuente de las demencias. Aunque existe una presentación temprana asociada a 3 genes de tipo autosómico dominante, estos solo explican entre el 1 al 2% de todos los casos.
Nórbel Román Garita +1 more
doaj +1 more source
Uncorking AMPA receptors [PDF]
Journal of General Physiology, 2017 New JGP study explains how auxiliary proteins relieve polyamine block of AMPARs.
openaire +2 more sources
Gating Modes in AMPA Receptors [PDF]
The Journal of Neuroscience, 2010 AMPA receptors are ligand-gated ion channels that show multiple conductance levels, indicating that gating of individual AMPA subunits is to some extent independent of the other subunits. To study AMPAR subunit interactions during activation gating, we recorded from single channels in the absence of channel block and desensitization and at negative and
Lonnie P. Wollmuth, Martin Loynaz Prieto
openaire +3 more sources
Pelatihan Penyusunan Perangkat Ajar Kurikulum Merdeka bagi Guru-guru PAUD [PDF]
, 2023 Kegiatan PKM ini bertujuan untuk memberikan solusi terhadap permasalahan yang dihadapi oleh mitra yaitu kurangnya pemahaman tentang implementasi kurikulum Merdeka khususnya dalam merancang dan menyusun perangkat ajar Kurikulum Merdeka di Satuan PAUD ...
Ampa, Andi Tenri, Romba, Sri Sufliati
core +2 more sources