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AMPA receptor biogenesis and trafficking
Current Opinion in Neurobiology, 2007 AMPA-type glutamate receptors mediate the majority of fast excitatory transmission in the central nervous system. The trafficking of AMPA receptors to and from synapses alters synaptic strength and has been recognized as a central mechanism underlying various forms of synaptic plasticity.
Greger, Ingo H., Esteban, José A.
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Frontiers in Synaptic Neuroscience, 2021 The amygdala plays a crucial role in attaching emotional significance to environmental cues. Its intercalated cell masses (ITC) are tight clusters of GABAergic neurons, which are distributed around the basolateral amygdala complex.
Anna Seewald +6 more
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Channel opening and gating mechanism in AMPA-subtype glutamate receptors
Nature, 2017 AMPA (α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid)-subtype ionotropic glutamate receptors mediate fast excitatory neurotransmission throughout the central nervous system.
E. C. Twomey +4 more
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Dera Natung Government College Research Journal, 2016 The investigators conducted a study to know the attitude towards Human Rights Edu- cation and Peace Education of pre-service secondary teachers of Department of Education, Rajiv Gandhi University, Hills College of Teacher Education and Donyi-Polo B.Ed ...
Sony Dupak, Tage Ampa
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Exogenous AMPA downregulates gamma-frequency network oscillation in CA3 of rat hippocampal slices
Scientific Reports, 2023 Pharmacologically-induced persistent hippocampal γ oscillation in area CA3 requires activation of α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptors (AMPARs). However, we demonstrated that exogenous AMPA dose-dependently inhibited carbachol (CCH)-
Chengzhang Li +11 more
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Dissecting the Activation of AMPA Receptors [PDF]
Biophysical Journal, 2013 Ionotropic glutamate receptors are tetrameric ion channels that are activated by the neurotransmitter glutamate at excitatory synapses. It is known that after the binding of glutamate, the AMPA-subtype of glutamate receptors transits through distinct functional states to become fully activated, however, the conformations sampled by the tetramer during ...
Andrew J.R. Plested +6 more
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Postsynaptic Synaptotagmins Mediate AMPA Receptor Exocytosis During LTP
Nature, 2017 Strengthening of synaptic connections by NMDA (N-methyl-d-aspartate) receptor-dependent long-term potentiation (LTP) shapes neural circuits and mediates learning and memory.
Dick Wu +8 more
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AMPA Receptor Activation [PDF]
Neuron, 2004 AMPA receptors are tetramers assembled as a dimer-of-dimers with a 2-fold rotational symmetry in their extracellular domains. Two papers in this issue of Neuron, by Horning and Mayer and Sobolevsky et al., provide complementary data that extend this view and highlight the role of dimers in channel gating.
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BMC Cell Biology, 2012 Background AmpA is a secreted 24Kd protein that has pleiotropic effects on Dictyostelium development. Null mutants delay development at the mound stage with cells adhering too tightly to the substrate.
Noratel Elizabeth F +5 more
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Structure Elucidation and Immunoactivity Study of Armillaria mellea Fruiting Body Polysaccharides
Separations, 2023 Polysaccharides are the main nutritional constituents in the Armillaria mellea fruiting bodies. The structure and immunoactivity of Armillaria mellea polysaccharide are valuable to be determined for development. In the present study, two polysaccharides,
Qingqing Li +6 more
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