Results 171 to 180 of about 100,721 (313)

Regulation of AMPA Receptor Trafficking by Protein Ubiquitination [PDF]

open access: gold, 2017
Jocelyn Widagdo   +3 more
openalex   +1 more source

HSDL2 Suppresses Epileptic Seizures Through Phosphorylation‐Dependent Modulation of the PSD95‐NMDAR Signaling Axis

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 3, March 2026.
In a kainic acid‐induced mouse model of epilepsy, upregulation of HSDL2 in the hippocampus prolonged seizure latency, increased the membrane expression of PSD95, and enhanced its phosphorylation. Concurrently, HSDL2 attenuated the interaction between PSD95 and the NMDAR subunits GluN2A/GluN2B, thereby suppressing NMDAR overactivation, reducing ...
Yan Xia   +5 more
wiley   +1 more source

Tocotrienols: A Review From Source to Therapeutic Applications

open access: yesFood Frontiers, Volume 7, Issue 2, March 2026.
Tocotrienols demonstrate superior antioxidant, neuroprotective, and anti‐inflammatory properties compared to conventional vitamin E forms, with promising therapeutic applications across multiple disorders when delivered through optimized systems that enhance their inherently limited bioavailability.
Natalia‐Carolina Londoño   +6 more
wiley   +1 more source

Prolonged esophageal acid exposures induce synaptic downscaling of cortical membrane AMPA receptor subunits in rats

open access: green, 2016
Banani Banerjee   +7 more
openalex   +1 more source

Mechanisms of spinal glial activation in chemotherapy‐induced peripheral neuropathy: Focus on microglia and astrocytes

open access: yesIbrain, Volume 12, Issue 1, Page 65-85, Spring 2026.
Chemotherapy‐induced peripheral neuropathy (CIPN) remains a major clinical challenge, with central sensitization considered an important pathological mechanism in its occurrence and persistence. This review focuses on spinal astrocytes and microglia, systematically summarizing the pathological mechanisms of spinal glial cells involved in CIPN caused by
Long Gu, Song Cao, Yonghuai Feng
wiley   +1 more source

Involvement of the AMPA/kainate receptor in neuronal damage induced by focal cerebral ischemia in cats : protective effects of YM90K.

open access: diamond, 1994
Masayasu Takahashi   +6 more
openalex   +1 more source

Potential neuroprotective and therapeutic agents and their mechanisms for irradiation‐induced brain injury

open access: yesIbrain, Volume 12, Issue 1, Page 96-122, Spring 2026.
In this review, agents such baicalein, troxerutin, epigallocatechin gallate, quercetin, melatonin, valproic acid, lithium, neurosteroid progesterone, as well as minocycline have been implicated as neuroprotective agents for irradiation‐induced neurological deficits. Also, agents such as glucocorticoids, methylphenidate, vitamin E, bisdemethoxycurcumin,
Seidu A. Richard   +2 more
wiley   +1 more source

Claudin 24-A novel enhancer of AMPA receptor fidelity. [PDF]

open access: yesSci Adv
Strasdeit T   +21 more
europepmc   +1 more source

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