Results 171 to 180 of about 2,334,241 (398)

Synaptic and nonsynaptic localization of the GluR1 subunit of the AMPA- type excitatory amino acid receptor in the rat cerebellum [PDF]

open access: hybrid, 1994
Agnès Baude   +4 more
openalex   +1 more source

Effectiveness and safety of perampanel for pediatric patients with epilepsy: A real‐world study from China

open access: yesPediatric Investigation, EarlyView.
The 50% responder rate and seizure freedom rate after 6 months of PER treatment during routine clinical care were 70.4% and 22.1%, respectively. The 50% responder rates for the 3 age‐based cohorts were 64.5% in infants and young children, 73.4% in children and 69.2% in adolescents, and the Seizure‐freedom rates were 16.1%, 23.7% and 25.6% respectively.
Xiaohui Wang   +20 more
wiley   +1 more source

Multiple Routes for Glutamate Receptor Trafficking: Surface Diffusion and Membrane Traffic Cooperate to Bring Receptors to Synapses [PDF]

open access: yesScience's STKE (electronic resource) : signal transduction knowledge environment 327 (21/03/2006) 13, 2007
Trafficking of glutamate receptors into and out of synapses is critically involved in the plasticity of excitatory synaptic transmission. Endocytosis and exocytosis of receptors have initially been thought to account alone for this trafficking. However, membrane proteins also traffic through surface lateral diffusion in the plasma membrane. We describe
arxiv  

Increased AMPA-sensitive quisqualate receptor binding and reduced NMDA receptor binding in epileptic human hippocampus [PDF]

open access: hybrid, 1991
D. A. Hosford   +7 more
openalex   +1 more source

The δ2 glutamate receptor gates long-term depression by coordinating interactions between two AMPA receptor phosphorylation sites

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2013
Significance Long-term depression (LTD) commonly affects learning and memory in various brain regions. Although LTD in the cerebellum absolutely requires δ2 glutamate receptors, its underlying mechanisms remain elusive.
K. Kohda   +5 more
semanticscholar   +1 more source

Successful seizure control with cenobamate in juvenile myoclonic epilepsy

open access: yes
Epileptic Disorders, EarlyView.
Dalma Tényi   +2 more
wiley   +1 more source

Endogenous Dopamine and Endocannabinoid Signaling Mediate Cocaine-Induced Reversal of AMPAR Synaptic Potentiation in the Nucleus Accumbens Shell [PDF]

open access: yes, 2018
Repeated exposure to drugs of abuse alters the structure and function of neural circuits mediating reward, generating maladaptive plasticity in circuits critical for motivated behavior.
Ingebretson, Anna E.   +3 more
core   +3 more sources

Cyclic AMP and synaptic activity-dependent phosphorylation of AMPA- preferring glutamate receptors [PDF]

open access: hybrid, 1994
Craig Blackstone   +4 more
openalex   +1 more source

The Effect of Advancing Age and Intraocular Pressure Injury on Retinal Ganglion Cell Function and Synaptic Connectivity

open access: yesAging Cell, EarlyView.
The effect of advancing age and intraocular pressure injury on retinal ganglion cell function and synaptic connectivity. While young mice modulate their synaptic input to recover retinal ganglion cell function following injury, older mice compensate by altering their action potential threshold and axon initial segment (AIS) length to increase intrinsic
Vicki Chrysostomou   +9 more
wiley   +1 more source

S-palmitoylation regulates AMPA receptors trafficking and function: a novel insight into synaptic regulation and therapeutics

open access: yesActa Pharmaceutica Sinica B, 2015
Glutamate acting on AMPA-type ionotropic glutamate receptor (AMPAR) mediates the majority of fast excitatory synaptic transmission in the mammalian central nervous system.
Jun Han   +3 more
doaj   +1 more source

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