Results 191 to 200 of about 2,334,241 (398)

Differential Dependence on GluR2 Expression of Three Characteristic Features of AMPA Receptors [PDF]

, 1997
Mark Washburn, Markus Numberger, Sunan Zhang, Raymond Dingledine   +3 more
openalex   +1 more source

Neuroprotection for neonatal hypoxic–ischemic encephalopathy: A review of novel therapies evaluated in clinical studies

Developmental Medicine &Child Neurology, EarlyView.
Hypoxic‐ischemic encephalopathy (HIE) is a neurologic condition that is caused by insufficient oxygen and blood flow to a newborn infant’s brain. Although therapeutic hypothermia can reduce the degree of brain injury in some infants with HIE, many infants with HIE will have significant lifelong disabilities despite receiving this treatment.
Natalie H. Chan, Cheryl C. Hawkins, Benjamin V. Rodrigues, Marie‐Coralie Cornet, Fernando F. Gonzalez, Yvonne W. Wu   +5 more
wiley   +1 more source

Steroid Receptors and Vertebrate Evolution [PDF]

arXiv, 2019
Considering that life on earth evolved about 3.7 billion years ago, vertebrates are young, appearing in the fossil record during the Cambrian explosion about 542 to 515 million years ago. Results from sequence analyses of genomes from bacteria, yeast, plants, invertebrates and vertebrates indicate that receptors for adrenal steroids (aldosterone ...
arxiv  

Increased Hippocampal AMPA and NMDA Receptor Subunit Immunoreactivity in Temporal Lobe Epilepsy Patients [PDF]

, 1998
Gary W. Mathern, James K. Pretorius, Delia Mendoza, Alana Lozada, João Pereira Leite, Leila Chimelli, Itzhak Fried, Américo Ceiki Sakamoto, João Alberto Assirati, P. David Adelson   +9 more
openalex   +1 more source

Stargazin and AMPA receptor membrane expression is increased in the somatosensory cortex of Genetic Absence Epilepsy Rats from Strasbourg

Neurobiology of Disease, 2011
Absence-like seizures in the Genetic Absence Epilepsy Rats from Strasbourg (GAERS) model are believed to arise in hyperexcitable somatosensory cortical neurons, however the cellular basis of this increased excitability remains unknown. We have previously
J.T.T. Kennard, R. Barmanray, S. Sampurno, E. Ozturk, C.A. Reid, L. Paradiso, G.M. D'Abaco, A.H. Kaye, S.J. Foote, T.J. O'Brien, K.L. Powell   +10 more
doaj  

Neural mass modeling reveals that hyperexcitability underpins slow‐wave sleep changes in children with epilepsy

Epilepsia, EarlyView.
Abstract Objective The relationship between sleep and epilepsy is important but imperfectly understood. We sought to understand the mechanisms that explain the differences in sleep homeostasis observed in children with epilepsy. Methods We used a neural mass model to replicate sleep electroencephalography (EEG) recorded from 15 children with focal ...
Dominic M. Dunstan, Samantha Y. S. Chan, Marc Goodfellow   +2 more
wiley   +1 more source

The AMPA Receptor Code of Synaptic Plasticity

Neuron, 2018
Graham H. Diering, R. Huganir
semanticscholar   +1 more source

The cerebellum in epilepsy

Epilepsia, EarlyView.
Abstract The cerebellum, a subcortical structure, is traditionally linked to sensorimotor integration and coordination, although its role in cognition and affective behavior, as well as epilepsy, is increasingly recognized. Cerebellar dysfunction in patients with epilepsy can result from genetic disorders, antiseizure medications, seizures, and seizure‐
Christopher Elder, Rebecca Kerestes, Puneet Opal, Maria Marchese, Orrin Devinsky   +4 more
wiley   +1 more source

A Scoping Review of Corticosterone-Induced Changes in Ionotropic Glutamate Receptor Levels and Localization in the Rodent Brain: Implications for the Auditory System

Brain Sciences
Background: The ionotropic glutamate receptor AMPA (AMPAR) mediates fast excitatory synaptic transmission and regulates synaptic strength in various parts of the CNS.
Elsa Edlund, Ewa Domarecka, Heidi Olze, Agnieszka Szczepek   +3 more
doaj   +1 more source

NMDA Induces Long-Term Synaptic Depression and Dephosphorylation of the GluR1 Subunit of AMPA Receptors in Hippocampus [PDF]

, 1998
Hey‐Kyoung Lee, Kimihiko Kameyama, Richard L. Huganir, Mark F. Bear   +3 more
openalex   +1 more source