Results 51 to 60 of about 1,291,656 (247)
Data_Sheet_2_Molecular Characterization of AMPA-Receptor-Containing Vesicles.PDF
, 2021 Regulated delivery of AMPA receptors (AMPARs) to the postsynaptic membrane is an essential step in synaptic strength modification, and in particular, long-term potentiation (LTP).
John Jacob Peters (11567953) +4 more
core +1 more source
Neuromorphic Devices and Computing for Sensing, Memory, and Control
Advanced Science, EarlyView.This review introduces neuromorphic devices made from diverse materials. These devices mimic neuronal functions and architectures and, when integrated with artificial or biological computing, can form closed loops with neurons for pressure, optical, acoustic, and biochemical sensing and modulation.
Zhengguang Zhu +2 more
wiley +1 more source
Advanced Science, EarlyView.ABSTRACT Beta‐amyloid peptide (Aβ)‐induced suppression of hippocampal GABAergic interneuron activity drives hyperexcitability, amyloid pathology, and cognitive impairment in Alzheimer's disease (AD), suggesting that enhancing hippocampal inhibition may be protective.
Rahmi Lee +3 more
wiley +1 more source
Kainate receptor function in rodent subcortical visual processing. [PDF]
, 2007 Glutamate is found throughout the central nervous system and has been shown to be an important excitatory neurotransmitter in the visual system. There are two subdivisions of receptor on which this ubiquitous neurotransmitter acts, metabotropic (mGluR ...
Pothecary, C.A.
core
Data_Sheet_4_Molecular Characterization of AMPA-Receptor-Containing Vesicles.PDF
, 2021 Regulated delivery of AMPA receptors (AMPARs) to the postsynaptic membrane is an essential step in synaptic strength modification, and in particular, long-term potentiation (LTP).
John Jacob Peters (11567953) +4 more
core +1 more source
Advanced Science, EarlyView.Neuronal activation leads to astrocytic transient volume changes, activating transient receptor potential ankyrin 1 (TRPA1) channels, leading to Ca2+ influx. Activation of TRPA1 causes the release of D‐serine through BEST1. Finally, the augmented extracellular levels of D‐serine boost neuronal activity by binding GluN1‐containing NMDARs, leading to CBV
Kayoung Han +11 more
wiley +1 more source
Regulation of metabotropic glutamate receptor subtype 7a by PDZ-domain protein PICK1 [PDF]
, 2007 Metabotropic glutamate receptor subtype 7 (mGluR7) belongs to the family of G-protein coupled receptors. mGluR7 is widely distributed in the brain and primarily localized at presynaptic terminals, where it is thought to regulate neurotransmitter release ...
Zhang, C., Zhang, Chuansheng
core
Characterization of the functional role of the N-glycans in the AMPA receptor ligand-binding domain
, 2003 The ligand-binding domains of AMPA receptor subunits carry two conserved N-glycosylation sites. In order to gain insight into the functional role of the corresponding N-glycans, we examined how the elimination of glycosylation at these sites (N407 and ...
Sarah K. Coleman +7 more
core +1 more source
Advanced Science, EarlyView.The mechanisms of microRNA cargo sorting to extracellular vesicles, important mediators of cell communication, are not fully understood. This study reveals that the microRNA‐production machinery acts as a ‘hub’ for the sorting of microRNAs to extracellular vesicles, a process regulated by dynamic organelle interactions.
Yuzhou Zeng +6 more
wiley +1 more source
p97 regulates GluA1 homomeric AMPA receptor formation and plasma membrane expression
Nature Communications, 2019 AMPA receptors mediate excitatory synaptic transmission and are involved in synaptic plasticity. The authors show that p97 interacts with the GluA1 subunit of AMPA receptors, promotes the formation of GluA1 homomeric AMPA receptors, and regulates AMPA ...
Yuan Ge +10 more
doaj +1 more source