Results 171 to 180 of about 53,245 (286)

Fast Interneuron Dysfunction in Laminar Neural Mass Model Reproduces Alzheimer's Oscillatory Biomarkers

open access: yesHuman Brain Mapping, Volume 47, Issue 1, January 2026.
A computational laminar model links fast interneuron dysfunction to early hyperexcitability and late hypoactivity in Alzheimer's disease, reproducing key M/EEG biomarkers and capturing the disease's biphasic electrophysiological progression. ABSTRACT Early‐stage AD involves cortical hyperexcitability, progressing to oscillatory slowing and hypoactivity.
Roser Sanchez‐Todo   +5 more
wiley   +1 more source

Glutamate-Dependent Dynamic DNA Methylation Regulates Excitatory Amino Acid Transporters in Bergmann Glia Cells: Role of AMPA Receptors. [PDF]

open access: yesASN Neuro
Oyetayo BO   +11 more
europepmc   +1 more source

Afferent convergence to a shared population of interneuron AMPA receptors. [PDF]

open access: yesNat Commun, 2023
Pennock RL   +5 more
europepmc   +1 more source

Glutamate Receptors and Synaptic Plasticity in Health and Disease: A Personal Journey

open access: yesHippocampus, Volume 36, Issue 1, January 2026.
ABSTRACT I describe my progress in understanding synaptic plasticity in the hippocampus. Over the decades my lab has focused on the roles of glutamate receptors (AMPARs, NMDARs, mGluRs and KARs) and associated signaling molecules in LTP and LTD. Most of our studies have been conducted in area CA1 (Schaffer collateral—commissural pathway) with some ...
Graham L. Collingridge
wiley   +1 more source

Modeling the use of transient ligand binding information by AMPA receptors. [PDF]

open access: yesNPJ Syst Biol Appl
Braunstein H   +2 more
europepmc   +1 more source

A Novel NLRP3 Inhibitor AMS‐17 Rescues Deficits in Long‐Term Potentiation Following Mild Traumatic Brain Injury in Adult C57Bl/6 Mice

open access: yesHippocampus, Volume 36, Issue 1, January 2026.
ABSTRACT Traumatic brain injury (TBI) is a leading cause of long‐term disability, with limited effective treatment options. A key factor of TBI pathophysiology is neuroinflammation, which can involve the activation of the nucleotide‐binding domain leucine‐rich repeat protein 3 (NLRP3) inflammasome. Aberrant inflammation following injury has the ability
Eric Eyolfson   +7 more
wiley   +1 more source

Home - About - Disclaimer - Privacy